Submissions from 2016
Virucidal Activity of Human Α- and Β-defensins against Hepatitis C Virus Genotype 4, Ehab H. Mattar, Hussein A. Almehdar, Vladimir N. Uversky, and Elrashdy M. Redwan
Antimicrobial Potentials and Structural Disorder of Human and Animal Defensins, Ehab H. Mattar, Hussein A. Almehdar, Haitham A. Yacoub, Vladimir N. Uversky, and Elrashdy M. Redwan
Substitutions of Amino Acids with Large Number of Contacts in the Native State Have No Effect on the Rates of Protein Folding, Bogdan S. Melnik, Galina S. Nagibina, Anatoly S. Glukhov, Tatiana N. Melnik, and Vladimir N. Uversky
Compartmentalization and Functionality of Nuclear Disorder: Intrinsic Disorder and Protein-Protein Interactions in Intra-Nuclear Compartments, Fanchi Meng, Insung Na, Lukasz Kurgan, and Vladimir N. Uversky
Troponins, Intrinsic Disorder, and Cardiomyopathy, Insung Na, Min J. Kong, Shelby Straight, Jose R. Pinto, and Vladimir N. Uversky
Autophagy-related Intrinsically Disordered Proteins in Intra-nuclear Compartments, Insung Na, Fanchi Meng, Lukasz Kurgan, and Vladimir N. Uversky
Protein Cross-Linking Capillary Electrophoresis for Protein–Protein Interaction Analysis, Claire M. Ouimet, Hao Shao, Jennifer N. Rauch, Mohamed Dawod, Bryce Nordhues, Chad A. Dickey, Jason E. Gestwicki, and Robert T. Kennedy
Genes Encoding Intrinsic Disorder in Eukaryota Have High GC Content, Zhenling Peng, Vladimir N. Uversky, and Lukasz Kurgan
Prediction of Disordered RNA, DNA, and Protein Binding Regions Using DisoRDPbind, Zhenling Peng, Chen Wang, Vladimir N. Uversky, and Lukasz Kurgan
Disorder in Milk Proteins: α -lactalbumin. Part A. Structural Properties and Conformational Behavior, Eugene A. Permyakov, Sergei E. Permyakov, Leonid Breydo, Elrashdy Redwan, Hussein Almehdar, and Vladimir N. Uversky
Interleukin-11: A Multifunctional Cytokine with Intrinsically Disordered Regions, Eugene A. Permyakov, Vladimir N. Uversky, and Sergei E. Permyakov
Polymorphism of the Cysteine Protease YopT from Yersinia Pestis, Mikhail E. Platonov, Tat’yana E. Svetoch, Vera V. Evseeva, Anastasiya I. Knyazeva, Svetlana V. Dentovskaya, Vladimir L. Motin, Vladimir N. Uversky, and Andrey P. Anisimov
Structure and Function Relationships of Proteins Based on Polar Profile: A Review, Carlos Polanco, Thomas Buhse, and Vladimir N. Uversky
Classifying Lipoproteins Based on Their Polar Profiles., Carlos Polanco, Jorge Alberto Castañón-González, Thomas Buhse, Vladimir N. Uversky, and Rafael Zonana Amkie
α-lactalbumin: Of Camels and Cows, Jeniffer M. Redington, Leonid Breydo, Hussein A. Almehdar, Elrashdy M. Redwan, and Vladimir N. Uversky
Significant Antibacterial Activity and Synergistic Effects of Camel Lactoferrin with Antibiotics against Methicillin-resistant Staphylococcus aureus (MRSA), Elrashdy M. Redwan, Nawal Abd El-Baky, Ahmed M. Al-Hejin, Mohammed N. Baeshen, Hussein A. Almehdar, Abdulrahman Elsaway, Abu-Bakr M. Gomaa, Saad Berki Al-Masaudi, Fahad A. Al-Fassi, Isam Eldin AbuZeid, and Vladimir N. Uversky
Looking at the Carcinogenicity of Human Insulin Analogues via the Intrinsic Disorder Prism, Elrashdy M. Redwan, Moustafa H. Linjawi, and Vladimir N. Uversky
Hydrophobicity-dependent Effects of Polymers on Different Protein Conformations, Amanda E. Sales, Leonid Breydo, Tatiana S. Porto, Ana L. F. Porto, and Vladimir N. Uversky
Comparison of the Intrinsic Disorder Propensities of the RuBisCO Activase Enzyme from the Motile and Non-motile Oceanic Green Microalgae, Lucia Sena and Vladimir N. Uversky
Crystallographic Structure of Truncated CCL21 and the Putative Sulfotyrosine-Binding Site, Emmanuel W. Smith, Eric M. Lewandowski, Natasha A. Moussouras, Kyle G. Kroeck, Brian F. Volkman, Christopher T. Veldkamp, and Yu Chen
Structure-Based Identification of Novel Ligands Targeting Multiple Sites Within a Chemokine–G-Protein-Coupled-Receptor Interface, Emmanuel W. Smith, Amanda M. Nevins, Zhen Qiao, Yan Liu, Anthony E. Getschman, Sai L. Vankayala, M. Trent Kemp, Francis C. Peterson, Rongshi Li, Brian F. Volkman, and Yu Chen
Expression, Purification, and Characterization of Interleukin-11 Orthologues, Andrei S. Sokolov, Alexei S. Kazakov, Valery V. Solovyev, Ramis G. Ismailov, Vladimir N. Uversky, Yulia S. Lapteva, Roman V. Mikhailov, Ekaterina V. Pavlova, Iana O. Terletskaya, Ludmila V. Ermolina, Sergei E. Permyakov, Eugene A. Permyakov, and Eugene A. Permyakov
Peculiarities of the Super-folder GFP Folding in a Crowded Milieu, Olesia V. Stepanenko, Olga V. Stepanenko, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov
Protein Unfolding in Crowded Milieu: what Crowding Can Do to a Protein Undergoing Unfolding?, Olga V. Stepanenko, Olga I. Povarova, Anna I. Sulatskaya, Luisa A. Ferreira, Boris Y. Zaslavsky, Irina M. Kuznetsova, Konstantin K. information, and Vladimir N. information
Structure and Stability of Recombinant Bovine Odorant-binding Protein: II. Unfolding of the Monomeric Forms, Olga V. Stepanenko, Denis O. Roginski, Olesya V. Stepanenko, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov
Structure and Stability of Recombinant Bovine Odorant-binding Protein: I. Design and Analysis of Monomeric Mutants, Olga V. Stepanenko, Denis O. Roginskii, Olesya V. Stepanenko, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov
Structure and Stability of Recombinant Bovine Odorant-binding Protein: III. Peculiarities of the Wild Type bOBP Unfolding in Crowded Milieu, Olga V. Stepanenko, Denis O. Roginskii, Olesya V. Stepanenko, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov
Structure and Stability of Recombinant Bovine Odorant-binding Protein: II. Unfolding of the Monomeric Forms, Olga V. Stepanenko, Denis O. Roginskii, Olesya V. Stepanenko, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov
Macromolecular Crowders and Osmolytes Modulate the Structural and Catalytic Properties of Alkaline Molten Globular 5-aminolevulinate Synthase, Bosko M. Stojanovski, Leonid Breydo, Vladimir N. Uversky, and Gloria C. Ferreira
Murine Erythroid 5-aminolevulinate Synthase: Truncation of a Disordered N-terminal Extension is Not Detrimental for Catalysis, Bosko M. Stojanovski, Leonid Breydo, Vladimir N. Uversky, and Gloria C. Ferreira
The Unfolding Pathways of the Native and Molten Globule States of 5-aminolevulinate Synthase, Bosko M. Stojanovski, Leonid Breydo, Vladimir N. Uversky, and Gloria C. Ferreira
Dancing Protein Clouds: The Strange Biology and Chaotic Physics of Intrinsically Disordered Proteins, Vladimir N. Uversky
(Intrinsically Disordered) Splice Variants in the Proteome: Implications for Novel Drug Discovery, Vladimir N. Uversky
P53 Proteoforms and Intrinsic Disorder: An Illustration of the Protein Structure–function Continuum Concept, Vladimir N. Uversky
Paradoxes and Wonders of Intrinsic Disorder: Complexity of Simplicity, Vladimir N. Uversky
Disorder in Milk Proteins: α-lactalbumin. Part B. A Multifunctional Whey Protein Acting as an Oligomeric Molten Globular “Oil Container” in the Anti-tumorigenic Drugs, Liprotides, Vladimir N. Uversky, Sergei E. Permyakov, Leonid Breydo, Elrashdy M. Redwan, Hussein A. Almehdar, and Eugene A. Permyakov
Erythropoietin and Co.: Intrinsic Structure and Functional Disorder, Vladimir N. Uversky and Elrashdy M. Redwan
Disordered Nucleiome: Abundance of Intrinsic Disorder in the DNA- and RNA-binding Proteins in 1121 Species from Eukaryota, Bacteria and Archaea, Chen Wang, Vladimir N. Uversky, and Lukasz Kurgan
Functional Correlations of Respiratory Syncytial Virus Proteins to Intrinsic Disorder, Jillian N. Whelan, Krishna D. Reddy, Vladimir N Uversky, and Michael N. Teng
Functional Correlations of Respiratory Syncytial Virus Proteins to Intrinsic Disorder, Jillian N. Whelan, Krishna D. Reddy, Vladimir N. Uversky, and Michael N. Teng
Unfoldomes and Unfoldomics: Introducing Intrinsically Disordered Proteins, Bin Xue and Vladimir N. Uversky
Chicken Cathelicidins as Potent Intrinsically Disordered Biocides with Antimicrobial Activity against Infectious Pathogens, Haitham A. Yacoub, Ahmed M. Elazzazy, Maged M. Mahmoud, Mohamed Nabih Baeshen, Omar A. Al-Maghrabi, Saleh Alkarim, Ekram S. Ahmed, Hussein A. Almehdar, and Vladimir N. Uversky
Molecular Recognition Features (MoRFs) in Three Domains of Life, Jing Yan, A. Keith Dunker, Vladimir N. Uversky, and Lukasz Kurgan
Smoking Correlates with Increased Cytoskeletal Protein-related Coding Region Mutations in the Lung and Head and Neck Datasets of the Cancer Genome Atlas, John M. Yavorski and George Blanck
Nickel Impact on Human Health: An Intrinsic Disorder Perspective, Barbara Zambelli, Vladimir N. Uversky, and Stefano Ciurli
Analytical Applications of Partitioning in Aqueous Two-phase Systems: Exploring Protein Structural Changes and Protein–partner Interactions in Vitro and in Vivo by Solvent Interaction Analysis Method, Boris Y. Zaslavsky, Vladimir N. Uversky, and Arnon Chait
Solvent Interaction Analysis as a Proteomic Approach to Structure-based Biomarker Discovery and Clinical Diagnostics, Boris Y. Zaslavsky, Vladimir N. Uversky, and Arnon Chait
Submissions from 2015
Disorder in Milk Proteins: Structure, Functional Disorder, and Biocidal Potentials of Lactoperoxidase, Hussein A. Almehdar, Esmail M. El-Fakharany, Vladimir N. Uversky, and Elrashdy M. Redwan
Effects of Osmolytes on Protein-solvent Interactions in Crowded Environment: Analyzing the Effect of TMAO on Proteins in Crowded Solutions, Leonid Breydo, Amanda E. Sales, Luisa Ferreira, Olga Fedotoff, Marina P. Shevelyova, Sergei E. Permyakov, Kyle G. Kroeck, Eugene A. Permyakov, Boris Y. Zaslavsky, and Vladimir N. Uversky
Effects of Polymer Hydrophobicity on Protein Structure and Aggregation Kinetics in Crowded Milieu, Leonid Breydo, Amanda E. Sales, Telma Frege, Mark C. Howell, Boris Y. Zaslavsky, and Vladimir N. Uversky
Complexity of Aggregation Pathways of α-Synuclei, Leonid Breydo and Vladimir N. Uversky
Structural, Morphological, and Functional Diversity of Amyloid Oligomers, Leonid Breydo and Vladimir N. Uversky
Analysis of Partitioning of Organic Compounds and Proteins in Aqueous Polyethylene Glycol-sodium Sulfate Aqueous Two-phase Systems in Terms of Solute–solvent Interactions, Nuno R. da Silva, Luisa A. Ferreira, Pedro P. Madeira, José A. Teixeira, Vladimir N. Uversky, and Boris Y. Zaslavsky
Effect of Sodium Chloride on Solute–solvent Interactions in Aqueous Polyethylene Glycol–sodium Sulfate Two-phase Systems, Nuno R. da Silva, Luisa A. Ferreira, Pedro P. Madeira, José A. Teixeira, Vladimir N. Uversky, and Boris Y. Zaslavsky
Digested Disorder, Quarterly Intrinsic Disorder Digest (October-November-December, 2013), Shelly DeForte, Krishna D. Reddy, and Vladimir N. Uversky
Mechanistic and Structural Analysis of a Drosophila melanogaster Enzyme, Arylalkylamine N-Acetyltransferase Like 7, an Enzyme That Catalyzes the Formation of N-Acetylarylalkylamides and N-Acetylhistamine, Daniel R. Dempsey, Kristen A. Jeffries, Sumit Handa, Anne-Marie Carpenter, Santiago Rodriguez-Ospina, Leonid Breydo, and David J. Merkler
Increased High Mobility Group Protein A2/SMAD3 Relates to Ovarian Cancer Progression, Kimberly P. Dobrinski, Christina Diane Drenberg, Jeffrey L. Edelman, Stephanie T. Buttermore, Mai Mohamed, Vladimir N. Uversky, Mitchel S. Hoffman, Santo V. Nicosia, and Patricia A. Kruk
Intrinsic Disorder Mediates Hepatitis C Virus Core–host Cell Protein Interactions, Patrick T. Dolan, Andrew P. Roth, Bin Xue, Ren Sun, A. Keith Dunker, Vladimir N. Uversky, and Douglas J. LaCount
Human Consensus Interferons: Bridging the Natural and Artificial Cytokines with Intrinsic Disorder, Nawal Abd El-Baky, Vladimir N. Uversky, and Elrashdy M. Redwan
Solvent Properties of Water in Aqueous Solutions of Elastin-Like Polypeptide, Luisa A. Ferreira, James T. Cole, Christian Reichardt, Nolan B. Holland, Vladimir N. Uversky, and Boris Y. Zaslavsky
Analyzing the Effects of Protecting Osmolytes on Solute–water Interactions by Solvatochromic Comparison Method: II. Globular Proteins, Luisa A. Ferreira, Xiao Fan, Pedro P. Madeira, Lukasz Kurgan, Vladimir N. Uversky, and Boris Y. Zavlavsky
Effects of Osmolytes on Protein–solvent Interactions in Crowded Environments: Study of Sucrose and Trehalose Effects on Different Proteins by Solvent Interaction Analysis, Luisa A. Ferreira, Olga Fedotoff, Vladimir N. Uversky, and Boris Y. Zaslavsky
Responses of Proteins to Different Ionic Environment Are Linearly Interrelated, Luisa A. Ferreira, Pedro P. Madeira, Alexey V. Uversky, Vladimir N. Uversky, and Boris Y. Zaslavsky
Analyzing the Effects of Protecting Osmolytes on Solute–water Interactions by Solvatochromic Comparison Method: I. Small Organic Compounds, Luisa A. Ferreira, Pedro P. Madeira, Vladimir N. Uversky, and Boris Y. Zaslavsky
Human Erythroid 5-Aminolevulinate Synthase Mutations Associated with X-Linked Protoporphyria Disrupt the Conformational Equilibrium and Enhance Product Release, Erica J. Fratz, Jerome Clayton, Gregory A. Hunter, Sarah Ducamp, Leonid Breydo, Vladimir N. Uversky, Jean-Charles Deybach, Laurent Gouya, Hervé Puy, and Gloria C. Ferreira
Intrinsically Disordered Proteins in the Nucleus of Human Cells, Telma Frege and Vladimir N. Uversky
Detection of Links Between Ebola Nucleocapsid and Virulence Using Disorder Analysis, Gerard Kian-Meng Goh, A. Keith Dunker, and Vladimir N. Uversky
Shell Disorder, Immune Evasion and Transmission Behaviors Among Human and Animal Retroviruses, Gerard Kian-Meng Goh, A. Keith Dunker, and Vladimir N. Uversky
Intrinsic Disorder in Biomarkers of Insulin Resistance, Hypoadiponectinemia, and Endothelial Dysfunction among the Type 2 Diabetic Patients, Osama H. Jiffri, Fadwa M. Al-Sharif, Essam H. Jiffri, and Vladimir N. Uversky
Intrinsic Disorder in Biomarkers of Insulin Resistance, Hypoadiponectinemia, and Endothelial Dysfunction Among the Type 2 Diabetic Patients, Osama H. Jiffri, Fadwa M. Al-Sharif, Essam H. Jiffri, and Vladimir N. Uversky
“In-plant” NMR: Analysis of the Intact Plant Vesicularia Dubyana by High Resolution NMR Spectroscopy, Viktor P. Kutyshenko, Peter Beskaravayny, and Vladimir N. Uversky
Beyond the Excluded Volume Effects: Mechanistic Complexity of the Crowded Milieu, Irina M. Kuznetsova, Boris Y. Zaslavsky, Leonid Breydo, Konstantin K. Turoverov, and Vladimir N. Uversky
Antibacterial Properties and Atomic Resolution X-ray Complex Crystal Structure of a Ruthenocene Conjugated β-lactam Antibiotic, Eric M. Lewandowski, Joanna Skiba, Nicholas J. Torelli, Aleksandra Rajnisz, Jolanta Solecka, Konrad Kowalski, and Yu Chen
Pliable Natural Biocide: Jaburetox is an Intrinsically Disordered Insecticidal and Fungicidal Polypeptide Derived from Jack Bean Urease, Fernanda C. Lopes, Olena Dobrovolska, Rafael Real-Guerra, Valquiria Broll, Barbara Zambelli, Francesco Musiani, Vladimir N. Uversky, Célia R. Carlini, and Stefano Ciurli
Identification of Intrinsically Disordered Regions in PTEN and Delineation of Its Function via a Network Approach, Prerna Malaney, Vladimir N. Uversky, and Vrushank Davé
Unstructural Biology of the Dengue Virus Proteins, Fanchi Meng, Reaid A. Badierah, Hussein A. Almehdar, Elrashdy M. Redwan, Lukasz Kurgan, and Vladimir N Uversky
Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography, Derek A. Nichols, Jacqueline C. Hargis, Ruslan Sanishvili, Priyadarshini Jaishankar, Kyle Defrees, Emmanuel W. Smith, Kenneth K. Wang, Fabio Prati, Adam R. Renslo, H. Lee Woodcock, and Yu Chen
Exceptionally Abundant Exceptions: Comprehensive Characterization of Intrinsic Disorder in All Domains of Life, Zhenling Peng, Jing Yan, Xiao Fan, Marcin J. Mizianty, Bin Xue, Kui Wang, Gang Hu, Vladimir N. Uversky, and Lukasz Kurgan
Does Intrinsically Disordered Caldesmon Bind Calmodulin via the “buttons on a string” Mechanism?, Sergei E. Permyakov, Eugene A. Permyakov, and Vladimir N. Uversky
Does Intrinsically Disordered Caldesmon Bind Calmodulin via the “Buttons on a String” Mechanism?, Sergei E. Permyakov, Eugene A. Permyakov, and Vladimir N. Uversky
Intrinsically Disordered Caldesmon Binds Calmodulin via the “buttons on a string” Mechanism, Sergei E. Permyakov, Eugene A. Permyakov, and Vladimir N. Uversky
Identifying Similar Patterns of Structural Flexibility in Proteins by Disorder Prediction and Dynamic Programming, Aidan Petrovich, Adam Borne, Vladimir N. Uversky, and Bin Xue
Identification of Proteins Associated with Amyloidosis by Polarity Index Method., Carlos Polanco, José Lino Samaniego, Vladimir N N. Uversky, Jorge Alberto Castañón-González, Thomas Buhse, Marili Leopold-Sordo, Alejandro Madero-Arteaga, Alicia Morales-Reyes, Lourdes Tavera-Sierra, Jesus A. González-Bernal, and Miguel Arias-Estrada
Role of Monomer Arrangement in the Amyloid Self-assembly, Alexander Portillo, Mohtadin Hashemi, Yuliang Zhang, Leonid Breydo, Vladimir N. Uversky, and Yuri L. Lyubchenko
Globular Actin is a Partially Intrinsically Disordered Protein with a Quasi-Stationary Structure, Olga I. Povarova, Iuliia A. Gagarskaia, Vladimir N. Uversky, Irina M. Kuznetsova, and Konstantin K. Turoverov
High-resolution NMR Structure of a Zn2+-containing Form of the Bacteriophage T5 L-alanyl-D-glutamate Peptidase, Dmitry A. Prokhorov, Galina V. Mikoulinskaia, Nikolai V. Molochkov, Vladimir N. Uversky, and Victor P. Kutyshenko
Potential Antiviral Activities of Camel, Bovine, and Human Lactoperoxidases Against Hepatitis C Virus Genotype 4, Elrashdy M. Redwan, Hussein A. Almehdar, Esmail M. El-Fakharany, Abdul-Wahab K. Baig, and Vladimir N. Uversky
Disorder in Milk Proteins: Caseins, Intrinsically Disordered Colloids, Elrashdy M. Redwan, Bin Xue, Hussein A. Almehdar, and Vladimir N. Uversky
Hidden Disorder Propensity of the N-terminal Segment of Universal Adapter Protein 14-3-3 is Manifested in Its Monomeric Form: Novel Insights into Protein Dimerization and Multifunctionality, Nikolai N. Sluchanko and Vladimir N. Uversky
Structures of Pseudomonas aeruginosa LpxA Reveal the Basis for Its Substrate Selectivity, Emmanuel W. Smith, XiuJun Zhang, Cyrus Behzadi, Logan D. Andrews, Frederick Cohen, and Yu Chen
Structure and Stability of Recombinant Bovine Odorant-Binding Protein: I. Design and Analysis of Monomeric Mutants, Olga V. Stepanenko, Denis O. Roginskii, Olesya V. Stepanenko, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov
Structure and Stability of Recombinant Bovine Odorant-binding Protein: I. Design and Analysis of Monomeric Mutants, Olga V. Stepanenko, Denis O. Roginskii, Olesya V. Stepanenko, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov
Structure and Stability of Recombinant Bovine Odorant-binding Protein: II. Unfolding of the Monomeric Forms, Olga V. Stepanenko, Denis O. Roginskii, Olesya V. Stepanenko, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov
Biophysical Methods to Investigate Intrinsically Disordered Proteins: Avoiding an “Elephant and Blind Men” Situation, Vladimir N. Uversky
Biophysical Methods to Investigate Intrinsically Disordered Proteins: Avoiding an “Elephant and Blind Men” Situation, Vladimir N. Uversky
Commentary: Hot, Hotter, and Hottest Trends in α-synuclein Research, Vladimir N. Uversky
Functional Roles of Transiently and Intrinsically Disordered Regions Within Proteins, Vladimir N. Uversky
Intrinsically Disordered Proteins and Their (disordered) Proteomes in Neurodegenerative Disorders, Vladimir N. Uversky
Paradoxes and Wonders of Intrinsic Disorder: Prevalence of Exceptionality, Vladimir N. Uversky
Pliability of Protein Complexes and Complexity of Protein Pliability, Vladimir N. Uversky
