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Submissions from 2013

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Alpha 1-Antichymotrypsin, an Inflammatory Protein Overexpressed in the Brains of Patients with Alzheimer’s Disease, Induces Tau Hyperphosphorylation through c-Jun N-Terminal Kinase Activation, Ethika Tyagi, Tina Fiorelli, Michelle Norden, and Jaya Padmanabhan

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On the Intrinsic Disorder Status of the Major Players in Programmed Cell Death Pathways [Version 1; Peer Review: 2 Approved], Alexey V. Uversky, Bin Xue, Zhenling Peng, Lukasz Kurgan, and Vladimir N. Uversky

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A Decade and a Half of Protein Intrinsic Disorder: Biology Still Waits for Physics, Vladimir N. Uversky

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A Decade and a Half of Protein Intrinsic Disorder: Biology Still Waits for Physics, Vladimir N. Uversky

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Barium Binding to EF-hand Proteins and Potassium Channels, Vladimir N. Uversky

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Beryllium as Antigen, Vladimir N. Uversky

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Digested Disorder: Quarterly Intrinsic Disorder Digest (January/February/March, 2013), Vladimir N. Uversky

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Disorder in The Lifetime of a Protein, Vladimir N. Uversky

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Intrinsically Disordered Proteins, Vladimir N. Uversky

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Intrinsic Disorder-based Protein Interactions and Their Modulators, Vladimir N. Uversky

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Multidimensionality of Idims: Intrinsic Disorder in Autoinhibition, Vladimir N. Uversky

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Posttranslational Modification, Vladimir N. Uversky

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Strontium and DNA Aptamer Folding, Vladimir N. Uversky

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Strontium Binding to Proteins, Vladimir N. Uversky

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The Alphabet of Intrinsic Disorder: II. Various Roles of Glutamic Acid in Ordered and Intrinsically Disordered Proteins, Vladimir N. Uversky

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The Most Important Thing is The Tail: Multitudinous Functionalities of Intrinsically Disordered Protein Termini, Vladimir N. Uversky

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The UBE2E Proteins as Conjugating Dispersers: Extending Function with Extended Extensions, Vladimir N. Uversky

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Under-folded Proteins: Conformational Ensembles and Their Roles in Protein Folding, Function, and Pathogenesis, Vladimir N. Uversky

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Unusual Biophysics of Intrinsically Disordered Proteins, Vladimir N. Uversky

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The Case for Intrinsically Disordered Proteins Playing Contributory Roles in Molecular Recognition Without a Stable 3D Structure, Vladimir N. Uversky and A. Keith Dunker

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Methods in Protein Structure and Stability Analysis: Conformational Stability, Size, Shape and Surface of Protein Molecules, Vladimir N. Uversky and Eugene A. Permyakov

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Distribution and Cluster Analysis of Predicted Intrinsically Disordered Protein Pfam Domains, Robert W. Williams, Bin Xue, Vladimir N. Uversky, and A. Keith Dunker

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Actinidia DRM1 - An Intrinsically Disordered Protein Whose Mrna Expression Is Inversely Correlated with Spring Budbreak in Kiwifruit, Marion Wood, Georgina M. Rae, Rong-Mei Wu, Eric F. Walton, Bin Xue, Roger P. Hellens, and Vladimir N. Uversky

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Intrinsically Disordered Regions of P53 Family are Highly Diversified in Evolution, Bin Xue, Celeste J. Brown, A. Keith Dunker, and Vladimir N. Uversky

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Protein Intrinsic Disorder in The Acetylome of Intracellular and Extracellular Toxoplasma gondii, Bin Xue, Victoria Jeffers, William J. Sullivan Jr., and Vladimir N. Uversky

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Stochastic Machines as a Colocalization Mechanism for Scaffold Protein Function, Bin Xue, Pedro R. Romero, Maria Noutsou, Madelon M. Maurice, Stefan G.D. Rüdiger, Albert M. William Jr., Marcin J. Mizianty, Lukasz Kurgan, Vladimir N. Uversky, and A. Keith Dunker

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Structural Characterizations of Phosphorylatable Residues in Transmembrane Proteins from Arabidopsis Thaliana, Bin Xue and Vladimir N. Uversky

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RAPID: Fast and Accurate Sequence-based Prediction of Intrinsic Disorder Content on Proteomic Scale, Jing Yan, Marcin J. Mizianty, Paul L. Filipow, Vladimir N. Uversky, and Lukasz Kurgan

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High Throughput Characterization of Structural Differences Between Closely Related Proteins in Solution, Alexander Zaslavsky, Pedro P. Madeira, Leonid Breydo, Vladimir N. Uversky, Arnon Chait, and Boris Y. Zaslavsky

Submissions from 2012

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Peculiarities of Copper Binding to α-synuclein, Atta Ahmad, Colin S. Burns, Anthony L. Fink, and Vladimir N. Uversky

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Accurate Prediction of Protein Structural Classes Using Functional Domains and Predicted Secondary Structure Sequences, Amin Ahmadi Adl, Abbas Nowzari-Dalini, Bin Xue, Vladimir N. Uversky, and Xiaoning Qian

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α-synuclein Misfolding and Parkinson's Disease, Leonid Breydo, Jessica W. Wu, and Vladimir N. Uversky

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Morfpred, a Computational Tool for Sequence-based Prediction and Characterization of Short Disorder-to-order Transitioning Binding Regions in Proteins, Fatemeh Miri Disfani, Wei-Lun Hsu, Marcin J. Mizianty, Christopher J. Oldfield, Bin Xue, A. Keith Dunker, Vladimir N. Uversky, and Lukasz Kurgan

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Influence of Serum Proteins on Conformation of Prostate-specific Antigen, Olga Fedotoff, Larissa M. Mikheeva, Arnon Chait, Vladimir N. Uversky, and Boris Y. Zaslavsky

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Understanding Viral Transmission Behavior Via Protein Intrinsic Disorder Prediction: Coronaviruses, Gerard Kian-Meng Goh, A. Keith Dunker, and Vladimir N. Uversky

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Structural Disorder in Proteins from Influenza Virus, Gerard Kian-Meng Goh, A. Keith Dunker, and Vladimir N. Uversky

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Understanding Viral Transmission Behavior via Protein Intrinsic Disorder Prediction: Coronaviruses, Gerard Kian-Meng Goh, A. Keith Dunker, and Vladimir N. Uversky

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Structural Disorder in Matrix Proteins from Hiv-related Viruses, Gerard Kian-Meng Goh, Bin Xue, A. Keith Dunker, and Vladimir N. Uversky

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Common Features at the Start of the Neurodegeneration Cascade, Rubén Hervás, Javier Oroz, Albert Galera-Prat, Oscar Goñi, Alejandro Valbuena, Andrés M. Vera, Àngel Gómez-Sicilia, Fernando Losada-Urzáiz, Vladimir N. Uversky, Margarita Menéndez, Douglas V. Laurents, Marta Bruix, and Mariano Carrión-Vázquez

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Not That Rigid Midgets and Not So Flexible Giants: On The Abundance and Roles of Intrinsic Disorder in Short and Long Proteins, Mark Howell, Ryan Green, Alexis Ann Killeen, Lamar Wedderburn, Vincent Picascio, Alejandro Rabionet, Zhenling Peng, Maya Larina, Bin Xue, Lukasz Kurgan, and Vladimir N. Uversky

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High-throughput Characterization of Intrinsic Disorder in Proteins from The Protein Structure Initiative, Derrick E. Johnson, Bin Xue, Megan D. Sickmeier, Marc S. Cortese, Christopher J. Oldfield, Tanguy Le Gall, and Vladimir N. Uversky

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An Intrinsically Disordered Region of the Acetyltransferase P300 with Similarity to Prion-like Domains Plays a Role in Aggregation, Alexander Kirilyuk, Mika Shimoji, Jason Catania, Geetaram Sahu, Nagarajan Pattabiraman, Antonio Giordano, Christopher Albanese, Italo Mocchetti, Jeffrey A. Toretsky, Vladimir N. Uversky, and Maria Laura Avantaggiati

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Analyzing Thioflavin T Binding to Amyloid Fibrils by an Equilibrium Microdialysis-based Technique, Irina M. Kuznetsova, Anna I. Sulatskaya, Vladimir N. Uversky, and Konstantin K. Turoverov

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A New Trend in The Experimental Methodology for The Analysis of The Thioflavin T Binding to Amyloid Fibrils, Irina M. Kuznetsova, Anna I. Sulatskaya, Vladimir N. Uversky, and Konstantin K. Turoverov

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Molecular Profiling: an Essential Technology Enabling Personalized Medicine in Breast Cancer, Jiangang Liu, Shuyu Li, A. Keith Dunker, and Vladimir N. Uversky

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Ss-stabilizing Proteins Rationally: Intrinsic Disorder-based Design of Stabilizing Disulphide Bridges in GFP, Bogdan S. Melnik, Tatiana V. Povarnitsyna, Anatoly S. Glukhov, Tatiana N. Melnik, and Vladimir N. Uversky

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Denaturant-induced Conformational Transitions in Intrinsically Disordered Proteins, Paolo Neyroz, Stefano Ciurli, and Vladimir N. Uversky

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Denaturant-Induced Conformational Transitions in Intrinsically Disordered Proteins, Paolo Neyroz, Stefano Ciurli, and Vladimir N. Uversky

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Binding Promiscuity of Unfolded Peptides, Christopher J. Oldfield, Bin Xue, A. Keith Dunker, and Vladimir N. Uversky

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More Than Just Tails: Intrinsic Disorder in Histone Proteins, Zhenling Peng, Marcin J. Mizianty, Bin Xue, Lukasz Kurgan, and Vladimir N. Uversky

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Apolipoprotein E: Essential Catalyst of the Alzheimer Amyloid Cascade, Huntington Potter and Thomas Wisniewski

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Sweeping Away Protein Aggregation with Entropic Bristles: Intrinsically Disordered Protein Fusions Enhance Soluble Expression, Aron A. Santner, Carrie H. Croy, Farha H. Vasanwala, Vladimir N. Uversky, Ya-Yue J. Van, and A. Keith Dunker

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Fibrillation Mechanism of a Model Intrinsically Disordered Protein Revealed by 2D Correlation Deep UV Resonance Raman Spectroscopy, Vitali Sikirzhytski, Natalya I. Topilina, Gaius A. Takor, Seiichiro Higashiya, John T. Welch, Vladimir N. Uversky, and Igor K. Lednev

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Free Cysteine Modulates The Conformation of Human C/EBP Homologous Protein, Vinay K. Singh, Mona M. Rahman, Kim Munro, Vladimir N. Uversky, Steven P. Smith, and Zongchao Jia

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Binding Stoichiometry and Affinity of Fluorescent Dyes to Proteins in Different Structural States, Anna I. Sulatskaya, Olga I. Povarova, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov

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Binding Stoichiometry and Affinity of Fluorescent Dyes to Proteins in Different Structural States, Anna I. Sulatskaya, Olga I. Povarova, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov

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Applications of Bioinformatics and Experimental Methods to Intrinsic Disorder-based Protein-protein Interactions, Xiaolin Sun, William T. Jones, and Vladimir N. Uversky

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Analysis of the Tau-Associated Proteome Reveals That Exchange of Hsp70 for Hsp90 Is Involved in Tau Degradation, Andrea D. Thompson, K. Matthew Scaglione, John Prensner, Anne T. Gillies, Arul Chinnaiyan, Henry L. Paulson, Umesh Jinwal, Chad A. Dickey, and Jason E. Gestwicki

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Interactions Between The C-terminus of Kv1.5 and Kvβ Regulate Pyridine Nucleotide-Dependent Changes in Channel Gating, Srinicas M. Tipparaju, Xiao-Ping Li, Peter J. Kilfoil, Bin Xue, Vladimir N. Uversky, Aruni Bhatnagar, and Oleg A. Barski

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Disordered Competitive Recruiter: Fast and Foldable, Vladimir N. Uversky

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Intrinsically Disordered Proteins and Novel Strategies for Drug Discovery, Vladimir N. Uversky

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Size-exclusion Chromatography in Structural Analysis of Intrinsically Disordered Proteins, Vladimir N. Uversky

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Size-Exclusion Chromatography in Structural Analysis of Intrinsically Disordered Proteins, Vladimir N. Uversky

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Multiparametric Analysis of Intrinsically Disordered Proteins: Looking at Intrinsic Disorder Through Compound Eyes, Vladimir N. Uversky and A. Keith Dunker

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Intrinsically Disordered Proteins, Vladimir N. Uversky and A. Keith Dunker

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Why are We Interested in the Unfolded Peptides and Proteins?, Vladimir N. Uversky and A. Keith Dunker

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Protein Disorder and Human Genetic Disease, Vladimir N. Uversky, Lilia M. Iakoucheva, and A. Keith Dunker

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Length-dependent Compaction of Intrinsically Disordered Proteins, Vladimir N. Uversky, Carlo Santambrogio, Stefania Brocca, and Rita Grandori

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Disease-associated Mutations Disrupt Functionally Important Regions of Intrinsic Protein Disorder, Vladimir Vacic, Phineus R. L. Markwick, Christopher J. Oldfield, Xiaoyue Zhao, Chad Haynes, Vladimir N. Uversky, and Lilia M. Iakoucheva

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HSF Transcription Factor Family, Heat Shock Response, and Protein Intrinsic Disorder, Sandy D. Westerheide, Rachel Rene Raynes, Chase D Powell, Bin Xue, and Vladimir N. Uversky

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HSF Transcription Factor Family, Heat Shock Response, and Protein Intrinsic Disorder, Sandy D. Westerheid, Rachel Raynes, Chase D Powell, Bin Xue, and Vladimir N. Uversky

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Orderly Order in Protein Intrinsic Disorder Distribution: Disorder in 3500 Proteomes from Viruses and The Three Domains of Life, Bin Xue, A. Keith Dunker, and Vladimir N. Uversky

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The Roles of Intrinsic Disorder in Orchestrating The Wnt-pathway, Bin Xue, A. Keith Dunker, and Vladimir N. Uversky

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Protein Intrinsic Disorder as a Flexible Armor and a Weapon of HIV-1, Bin Xue, Marcin J. Mizianty, Lukasz Kurgan, and Vladimir N. Uversky

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Protein Intrinsic Disorder and Induced Pluripotent Stem Cells, Bin Xue, Christopher J. Oldfield, Ya-Yue J. Van, A. Keith Dunker, and Vladimir N. Uversky

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Local Flexibility Facilitates Oxidization of Buried Methionine Residues, Kuiran Xu, Vladimir N. Uversky, and Bin Xue

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Insights in The (Un)structural Organization of Bacillus Pasteurii Ureg, an Intrinsically Disordered Gtpase Enzyme, Barbara Zambelli, Nunilo Cremades, Paolo Neyroz, Paolo Turano, Vladimir N. Uversky, and Stefano Ciurli

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SPINE-D: Accurate Prediction of Short and Long Disordered Regions by a Single Neural-network Based Method, Tuo Zhang, Eshel Faraggi, Bin Xue, A. Keith Dunker, Vladimir N. Uversky, and Yaoqi Zhou

Submissions from 2011

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Mechanism of Resistance to Dietary Cholesterol, Lindsey R. Boone, Patricia A. Brooks, Melissa I. Niesen, and Gene C. Ness

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Role of Metal Ions in Aggregation of Intrinsically Disordered Proteins in Neurodegenerative Diseases, Leonid Breydo and Vladimir N. Uversky

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Regions of Intrinsic Disorder Help Identify a Novel Nuclear Localization Signal in toxoplasma Gondii Histone Acetyltransferase Tggcn5-b, Stacy E. Dixon, Micah M. Bhatti, Vladimir N. Uversky, A. Keith Dunker, and William J. Sullivan Jr.

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Resonance Raman Spectroscopic Examination of Ferrochelatase-induced Porphyrin Distortion, Ricardo Franco, Salam Al-Karadaghi, and Gloria C. Ferreira

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Characterization of The Non-fibrillar α-synuclein Oligomers, Dong-Pyo Hong, Shubo Han, Anthony L. Fink, and Vladimir N. Uversky

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Oligomers of α-synuclein in the Pathogenesis of Parkinson’s Disease, Dong-Pyo Hong, Wenbo Zhou, Aron A. Santner, and Vladimir N. Uversky

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Ferrochelatase: The Convergence of the Porphyrin Biosynthesis and Iron Transport Pathways, Gregory A. Hunter, Salam Al-Karadaghi, and Gloria C. Ferreira

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P3-124: Exploiting the Diversity of the Chaperone Repertoire to Treat Tauopathies, Umesh Jinwal, Jose Abisambra, John Koren, John O'Leary, Laura Blair, Shannon Hill, Justin Trotter, Martin Mushcol, Edwin Weeber, Jason Gestwicki, and Chad Dickey

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Analyzing and Mapping Sweat Metabolomics by High-resolution NMR Spectroscopy, Viktor P. Kutyshenko, Maxim Molchanov, Peter Beskaravayny, Vladimir N. Uversky, and Maria A. Timchenko

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Predictive Power Estimation Algorithm (PPEA) - A New Algorithm to Reduce Overfitting for Genomic Biomarker Discovery, Jiangang Liu, Robert A. Jolly, Aaron T. Smith, George H. Searfoss, Keith M. Goldstein, Vladimir N. Uversky, Keith Dunker, Shuyu Li, Craig E. Thomas, and Tao Wei

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Molecular Mechanisms of The Anomalous Thermal Aggregation of Green Fluorescent Protein, Bogdan S. Melnik, Nikolai V. Molochkov, Dmitry A. Prokhorov, Vladimir N. Uversky, and Victor P. Kutyshenko

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Sequential Melting of Two Hydrophobic Clusters Within The Green Fluorescent Protein Gfp-cycle3, Tatiana N. Melnik, Tatiana V. Povarnitsyna, Anatoly S. Glukhov, Vladimir N. Uversky, and Bogdan S. Melnik

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In-silico Prediction of Disorder Content Using Hybrid Sequence Representation, Marcin J. Mizianty, Tuo Zhang, Bin Xue, Yaoqi Zhou, A. Keith Dunker, Vladimir N. Uversky, and Lukasz Kurgan

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Protein Engineering of Metal Binding Proteins, Eugene A. Permyakov and Vladimir N. Uversky

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Intrinsic Disorder in S100 Proteins, Sergei E. Permyakov, Ramis G. Ismailov, Alexander I. Denesyuk, Vladimir N. Uversky, and Eugene A. Permyakov

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Intrinsic Disorder of The Extracellular Matrix, Franck Peysselon, Bin Xue, Vladimir N. Uversky, and Sylvie Richard-Blum

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Effects of HMGN Variants on The Cellular Transcription Profile, Mark Rochman, Leila Taher, Toshihiro Kurahashi, Srujana Cherukuri, Vladimir N. Uversky, David Landsman, Ivan Ovcharenko, and Michael Bustin

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Modulating α-synuclein Misfolding and Fibrillation in Vitro by Agrochemicals, Blanca A. Silva, Olöf Einarsdóttir, Anthony L. Fink, and Vladimir N. Uversky

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A Functionally Required Unfoldome from The Plant Kingdom: Intrinsically Disordered N-terminal Domains of GRAS Proteins are Involved in Molecular Recognition During Plant Development, Xiaolin Sun, Bin Xue, William T. Jones, Erik H. A. Rikkerink, A. Keith Dunker, and Vladimir N. Uversky

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Flexible Nets of Malleable Guardians: Intrinsically Disordered Chaperones in Neurodegenerative Diseases, Vladimir N. Uversky

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Intrinsically Disordered Chaperones and Neurodegeneration, Vladimir N. Uversky

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Intrinsically Disordered Proteins from A to Z, Vladimir N. Uversky