Submissions from 2013
Digested Disorder: Quarterly Intrinsic Disorder Digest (April - May - June, 2013, Shelly Deforte, Krishna D. Reddy, and Vladimir N. Uversky
What’s in a Name? Why These Proteins are Intrinsically Disordered, A. Keith Dunker; M. Madan Babu; Elisar Barbar; Martin Blackledge; Sarah E. Bondos; Zsuzsanna Dosztányi; H. Jane Dyson; Julie D. Forman-Kay; Monika Fuxreiter; Joerg Gsponer; Kyou-Hoon Han; David T. Jones; Sonia Longhi; Steven J. Metallo; Ken Nishikawa; Ruth Nussinov; Zoran Obradovic; Rohit V. Pappu; ,Burkhard Rost; Philipp Selenko; Vinod Subramaniam; Joel Sussman; Peter Tompa; and Vladimir N. Uversky
Effect of Salt Additives on Protein Partition in Polyethylene Glycol-sodium Sulfate Aqueous Two-phase Systems, Luisa Ferreira, Pedro P. Madeira, Larissa M. Mikheeva, Vladimir N. Uversky, and Boris Y. Zaslavsky
Understanding The Molecular Mechanisms Underlying Complex Cancer Genome Rearrangements, Robert Hedlund and Vladimir N. Uversky
Exploring The Binding Diversity of Intrinsically Disordered Proteins Involved in One-to-many Binding, Wei-Lun Hsu, Christopher J. Oldfield, Bin Xue, Jingwei Meng, Fei Huang, Pedro Romero, Vladimir N. Uversky, and A. Keith Dunker
Imbalance of Hsp70 Family Variants Fosters Tau Accumulation, Umesh K. Jinwal, Elias Akoury, Jose F. Abisambra, John C. O'Lery III, Andrea D. Thompson, Laura Blair, Ying Jin, Justin Bacon, Bryce Nordhues, Matthew Cockman, Juan Zhang, Pengfei Li, Bo Zhang, Sergiy Borysov, Vladimir N. Uversky, Jacek Biernat, Eckhard Mandelkow, Jason E. Gestwicki, Markus Zweckstetter, and Chad A. Dickey
Aminolaevulinic Acid Synthase of Rhodobacter capsulatus: High-resolution Kinetic Investigation of the Structural Basis for Substrate Binding and Catalysis, Anna-Lena Kaufholz, Gregory A. Hunter, Gloria C. Ferreira, Thomas Lendrihas, Vanessa Hering, Gunhild Layer, Martina Jahn, and Dieter Jahn
Looking at Microbial Metabolism by High-resolution (2)H-NMR Spectroscopy, Victor P. Kutyshenko, Peter M. Beskaravayny, Maxim V. Molchanov, Svetlana I. Paskevich, Dmitry A. Prokhorov, and Vladimir N. Uversky
Sequence Microheterogeneity of Parvalbumin, The Major Fish Allergen, Yulia S. Lapteva, Vladimir N. Uversky, and Sergei E. Permyakov
Intrinsic Disorder in PTEN and Its Interactome Confers Structural Plasticity and Functional Versatility, Prerna Malaney, Ravi Ramesh Pathak, Bin Xue, Vladimir N. Uversky, and Vrushank Davé
The Pten Long N-tail is Intrinsically Disordered: Increased Viability for Pten Therapy, Prerna Malaney, Vladimir N. Uversky, and Vrushank Davé
Intrinsic Disorder in Pathogen Effectors: Protein Flexibility as an Evolutionary Hallmark in a Molecular Arms Race, Macarena Marín, Vladimir N. Uversky, and Thomas Ott
Synthesis and Initial Evaluation of YM-08, a Blood-Brain Barrier Permeable Derivative of the Heat Shock Protein 70 (Hsp70) Inhibitor MKT-077, Which Reduces Tau Levels, Yoshinari Miyata, Xiaokai Li, Hsiu-Fang Lee, Umesh K. Jinwal, Sharan R. Srinivasan, Sandlin P. Seguin, Zapporah T. Young, Jeffrey L. Brodsky, Chad A. Dickey, Duxin Sun, and Jason E. Gestwicki
Alteration of Tropomyosin-binding Properties of Tropomodulin-1 Affects Its Capping Ability and Localization in Skeletal Myocytes, Natalia A. Moroz, Stefanie M. Novak, Richardo Azevedo, Mert Colpan, Vladimir N. Uversky, Carol C. Gregorio, and Alla S. Kostyukova
Ordered Disorder of the Astrocytic Dystrophin-associated Protein Complex in the Norm and Pathology, Insung Na, Derek Redmon, Markus Kopa, Yiru Qin, Bin Xue, and Vladimir N. Uversky
D2P2: Database of Disordered Protein Predictions, Matt E. Oates, Pedro R. Romero, Takashi Ishida, Mohamed Ghalwash, Marcin J. Mizianty, Bin Xue, Zsuzsanna Dosztányi, Vladimir N. Uversky, Zoran Obradovic, Lukasz Kurgan, A. Keith Dunker, and Julian Gough
Utilization of Protein Intrinsic Disorder Knowledge in Structural Proteomics, Christopher J. Oldfield, Bin Xue, Ya-Yue Van, Eldon L. Ulrich, John L. Markley, A. Keith Dunker, and Vladimir N. Uversky
Rapid Evolutionary Dynamics of Structural Disorder as a Potential Driving Force for Biological Divergence in Flaviviruses, Juan F. Ortiz, Madolyn L. MacDonald, Patrick Masterson, Vladimir N. Uversky, and Jessica Siltberg-Liberles
Persistent Human Herpesvirus-6 Infection in Patients with an Inherited Form of the Virus, Shara N. Pantry, Maria M. Medveczky, Jesse H. Arbuckle, Janos Luka, Jose G. Montoya, Jianhong Hu, Rolf Renne, Daniel Peterson, Joshua C. Pritchett, Dharam V. Ablashi, and Peter G. Medveczky
Resilience of Death: Intrinsic Disorder in Proteins Involved in The Programmed Cell Death, Z Peng, Bin Xue, Lukasz Kurgan, and Vladimir N. Uversky
The Use of Protein Engineering Methods for Studies of Calcium Binding Proteins, Eugene A. Permyakov and Vladimir N. Uversky
Malleable Ribonucleoprotein Machine: Protein Intrinsic Disorder in the Saccharomyces cerevisiae Spliceosome, Maria de Lourdes Coelho Ribeiro, Julio Espinosa, Sameen Islam, Osvaldo Martinez, Jayesh Jamnadas Thanki, Stephanie Mazariegos, Tam Nguyen, Maya Larina, Bin Xue, and Vladimir N. Uversky
Distinct β-Sheet Structure in Protein Aggregates Determined by Atr-ftir Spectroscopy, Bhavana Shivu, Sangita Seshadri, Jie Li, Keith A. Oberg, Vladimir N. Uversky, and Anthony L. Fink
Agrochemicals, α-synuclein, and Parkinson's Disease, Blanca A. Silva, Leonid Breydo, Anthony L. Fink, and Vladimir N. Uversky
Targeting The Chameleon: a Focused Look at α-synuclein and Its Roles in Neurodegeneration, Blanca A. Silva, Leonid Breydo, and Vladimir N. Uversky
Biophysical Characterization of α-Synuclein and Rotenone Interaction, Blanca A. Silva, Olöf Einarsdóttir, Anthony L. Fink, and Vladimir N. Uversky
The E3 Ubiquitin Ligase CHIP and the Molecular Chaperone Hsc70 Form a Dynamic, Tethered Complex, Matthew C. Smith, K. Matthew Scaglione, Victoria A. Assimon, Srikanth Patury, Andrea D. Thompson, Chad A. Dickey, Daniel R. Southworth, Henry L. Paulson, Jason E. Gestwicki, and Erik R. P. Zuiderweg
Multifarious Roles of Intrinsic Disorder in Proteins Illustrate Its Broad Impact on Plant Biology, Xiaolin Sun, Erik H. A. Rikkerink, William T. Jones, and Vladimir N. Uversky
Extracting Structural Information from Charge-state Distributions of Intrinsically Disordered Proteins by Non-denaturing Electrospray-ionization Mass Spectrometry, Lorenzo Testa, Stefania Brocca, Carlo Santambrogio, Annalisa D'Urzo, Johnny Habchi, Sonia Longhi, Vladimir N. Uversky, and Rita Grandori
The Alphabet of Intrinsic Disorder: I. Act Like a Pro: On the Abundance and Roles of Proline Residues in Intrinsically Disordered Proteins, Francois-Xavier Theillet, Lajos Kalmar, Peter Tompa, Kyou-Hoon Han, Philipp Selenko, A. Keith Dunker, Gary W. Daughdrill, and Vladimir N. Uversky
Immunotherapy for Gastrointestinal Malignancies, Paul G. Toomey, Nasreen A. Vohra, Tomar Ghansah, Amod A. Sarnaik, and Shari A. Pilon-Thomas
Targeting Gene Expression to the Female Larval Fat Body of Transgenic Aedes Aegypti Mosquitoes, D. C. Totten, M. Vuong, O. V. Litvinova, U. K. Jinwal, M. Gulia-Nuss, R. A. Harrell, and H. Beneš
Alpha 1-Antichymotrypsin, an Inflammatory Protein Overexpressed in the Brains of Patients with Alzheimer’s Disease, Induces Tau Hyperphosphorylation through c-Jun N-Terminal Kinase Activation, Ethika Tyagi, Tina Fiorelli, Michelle Norden, and Jaya Padmanabhan
On the Intrinsic Disorder Status of the Major Players in Programmed Cell Death Pathways [Version 1; Peer Review: 2 Approved], Alexey V. Uversky, Bin Xue, Zhenling Peng, Lukasz Kurgan, and Vladimir N. Uversky
A Decade and a Half of Protein Intrinsic Disorder: Biology Still Waits for Physics, Vladimir N. Uversky
A Decade and a Half of Protein Intrinsic Disorder: Biology Still Waits for Physics, Vladimir N. Uversky
Barium Binding to EF-hand Proteins and Potassium Channels, Vladimir N. Uversky
Beryllium as Antigen, Vladimir N. Uversky
Digested Disorder: Quarterly Intrinsic Disorder Digest (January/February/March, 2013), Vladimir N. Uversky
Disorder in The Lifetime of a Protein, Vladimir N. Uversky
Intrinsically Disordered Proteins, Vladimir N. Uversky
Intrinsic Disorder-based Protein Interactions and Their Modulators, Vladimir N. Uversky
Multidimensionality of Idims: Intrinsic Disorder in Autoinhibition, Vladimir N. Uversky
Posttranslational Modification, Vladimir N. Uversky
Strontium and DNA Aptamer Folding, Vladimir N. Uversky
Strontium Binding to Proteins, Vladimir N. Uversky
The Alphabet of Intrinsic Disorder: II. Various Roles of Glutamic Acid in Ordered and Intrinsically Disordered Proteins, Vladimir N. Uversky
The Most Important Thing is The Tail: Multitudinous Functionalities of Intrinsically Disordered Protein Termini, Vladimir N. Uversky
The UBE2E Proteins as Conjugating Dispersers: Extending Function with Extended Extensions, Vladimir N. Uversky
Under-folded Proteins: Conformational Ensembles and Their Roles in Protein Folding, Function, and Pathogenesis, Vladimir N. Uversky
Unusual Biophysics of Intrinsically Disordered Proteins, Vladimir N. Uversky
The Case for Intrinsically Disordered Proteins Playing Contributory Roles in Molecular Recognition Without a Stable 3D Structure, Vladimir N. Uversky and A. Keith Dunker
Methods in Protein Structure and Stability Analysis: Conformational Stability, Size, Shape and Surface of Protein Molecules, Vladimir N. Uversky and Eugene A. Permyakov
Distribution and Cluster Analysis of Predicted Intrinsically Disordered Protein Pfam Domains, Robert W. Williams, Bin Xue, Vladimir N. Uversky, and A. Keith Dunker
Actinidia DRM1 - An Intrinsically Disordered Protein Whose Mrna Expression Is Inversely Correlated with Spring Budbreak in Kiwifruit, Marion Wood, Georgina M. Rae, Rong-Mei Wu, Eric F. Walton, Bin Xue, Roger P. Hellens, and Vladimir N. Uversky
Intrinsically Disordered Regions of P53 Family are Highly Diversified in Evolution, Bin Xue, Celeste J. Brown, A. Keith Dunker, and Vladimir N. Uversky
Protein Intrinsic Disorder in The Acetylome of Intracellular and Extracellular Toxoplasma gondii, Bin Xue, Victoria Jeffers, William J. Sullivan Jr., and Vladimir N. Uversky
Stochastic Machines as a Colocalization Mechanism for Scaffold Protein Function, Bin Xue, Pedro R. Romero, Maria Noutsou, Madelon M. Maurice, Stefan G.D. Rüdiger, Albert M. William Jr., Marcin J. Mizianty, Lukasz Kurgan, Vladimir N. Uversky, and A. Keith Dunker
Structural Characterizations of Phosphorylatable Residues in Transmembrane Proteins from Arabidopsis Thaliana, Bin Xue and Vladimir N. Uversky
RAPID: Fast and Accurate Sequence-based Prediction of Intrinsic Disorder Content on Proteomic Scale, Jing Yan, Marcin J. Mizianty, Paul L. Filipow, Vladimir N. Uversky, and Lukasz Kurgan
High Throughput Characterization of Structural Differences Between Closely Related Proteins in Solution, Alexander Zaslavsky, Pedro P. Madeira, Leonid Breydo, Vladimir N. Uversky, Arnon Chait, and Boris Y. Zaslavsky
Submissions from 2012
Peculiarities of Copper Binding to α-synuclein, Atta Ahmad, Colin S. Burns, Anthony L. Fink, and Vladimir N. Uversky
Accurate Prediction of Protein Structural Classes Using Functional Domains and Predicted Secondary Structure Sequences, Amin Ahmadi Adl, Abbas Nowzari-Dalini, Bin Xue, Vladimir N. Uversky, and Xiaoning Qian
α-synuclein Misfolding and Parkinson's Disease, Leonid Breydo, Jessica W. Wu, and Vladimir N. Uversky
Morfpred, a Computational Tool for Sequence-based Prediction and Characterization of Short Disorder-to-order Transitioning Binding Regions in Proteins, Fatemeh Miri Disfani, Wei-Lun Hsu, Marcin J. Mizianty, Christopher J. Oldfield, Bin Xue, A. Keith Dunker, Vladimir N. Uversky, and Lukasz Kurgan
Influence of Serum Proteins on Conformation of Prostate-specific Antigen, Olga Fedotoff, Larissa M. Mikheeva, Arnon Chait, Vladimir N. Uversky, and Boris Y. Zaslavsky
Understanding Viral Transmission Behavior Via Protein Intrinsic Disorder Prediction: Coronaviruses, Gerard Kian-Meng Goh, A. Keith Dunker, and Vladimir N. Uversky
Structural Disorder in Proteins from Influenza Virus, Gerard Kian-Meng Goh, A. Keith Dunker, and Vladimir N. Uversky
Understanding Viral Transmission Behavior via Protein Intrinsic Disorder Prediction: Coronaviruses, Gerard Kian-Meng Goh, A. Keith Dunker, and Vladimir N. Uversky
Structural Disorder in Matrix Proteins from Hiv-related Viruses, Gerard Kian-Meng Goh, Bin Xue, A. Keith Dunker, and Vladimir N. Uversky
Common Features at the Start of the Neurodegeneration Cascade, Rubén Hervás, Javier Oroz, Albert Galera-Prat, Oscar Goñi, Alejandro Valbuena, Andrés M. Vera, Àngel Gómez-Sicilia, Fernando Losada-Urzáiz, Vladimir N. Uversky, Margarita Menéndez, Douglas V. Laurents, Marta Bruix, and Mariano Carrión-Vázquez
Not That Rigid Midgets and Not So Flexible Giants: On The Abundance and Roles of Intrinsic Disorder in Short and Long Proteins, Mark Howell, Ryan Green, Alexis Ann Killeen, Lamar Wedderburn, Vincent Picascio, Alejandro Rabionet, Zhenling Peng, Maya Larina, Bin Xue, Lukasz Kurgan, and Vladimir N. Uversky
High-throughput Characterization of Intrinsic Disorder in Proteins from The Protein Structure Initiative, Derrick E. Johnson, Bin Xue, Megan D. Sickmeier, Marc S. Cortese, Christopher J. Oldfield, Tanguy Le Gall, and Vladimir N. Uversky
An Intrinsically Disordered Region of the Acetyltransferase P300 with Similarity to Prion-like Domains Plays a Role in Aggregation, Alexander Kirilyuk, Mika Shimoji, Jason Catania, Geetaram Sahu, Nagarajan Pattabiraman, Antonio Giordano, Christopher Albanese, Italo Mocchetti, Jeffrey A. Toretsky, Vladimir N. Uversky, and Maria Laura Avantaggiati
Analyzing Thioflavin T Binding to Amyloid Fibrils by an Equilibrium Microdialysis-based Technique, Irina M. Kuznetsova, Anna I. Sulatskaya, Vladimir N. Uversky, and Konstantin K. Turoverov
A New Trend in The Experimental Methodology for The Analysis of The Thioflavin T Binding to Amyloid Fibrils, Irina M. Kuznetsova, Anna I. Sulatskaya, Vladimir N. Uversky, and Konstantin K. Turoverov
Molecular Profiling: an Essential Technology Enabling Personalized Medicine in Breast Cancer, Jiangang Liu, Shuyu Li, A. Keith Dunker, and Vladimir N. Uversky
Ss-stabilizing Proteins Rationally: Intrinsic Disorder-based Design of Stabilizing Disulphide Bridges in GFP, Bogdan S. Melnik, Tatiana V. Povarnitsyna, Anatoly S. Glukhov, Tatiana N. Melnik, and Vladimir N. Uversky
Denaturant-Induced Conformational Transitions in Intrinsically Disordered Proteins, Paolo Neyroz, Stefano Ciurli, and Vladimir N. Uversky
Denaturant-induced Conformational Transitions in Intrinsically Disordered Proteins, Paolo Neyroz, Stefano Ciurli, and Vladimir N. Uversky
Binding Promiscuity of Unfolded Peptides, Christopher J. Oldfield, Bin Xue, A. Keith Dunker, and Vladimir N. Uversky
More Than Just Tails: Intrinsic Disorder in Histone Proteins, Zhenling Peng, Marcin J. Mizianty, Bin Xue, Lukasz Kurgan, and Vladimir N. Uversky
Apolipoprotein E: Essential Catalyst of the Alzheimer Amyloid Cascade, Huntington Potter and Thomas Wisniewski
Sweeping Away Protein Aggregation with Entropic Bristles: Intrinsically Disordered Protein Fusions Enhance Soluble Expression, Aron A. Santner, Carrie H. Croy, Farha H. Vasanwala, Vladimir N. Uversky, Ya-Yue J. Van, and A. Keith Dunker
Fibrillation Mechanism of a Model Intrinsically Disordered Protein Revealed by 2D Correlation Deep UV Resonance Raman Spectroscopy, Vitali Sikirzhytski, Natalya I. Topilina, Gaius A. Takor, Seiichiro Higashiya, John T. Welch, Vladimir N. Uversky, and Igor K. Lednev
Free Cysteine Modulates The Conformation of Human C/EBP Homologous Protein, Vinay K. Singh, Mona M. Rahman, Kim Munro, Vladimir N. Uversky, Steven P. Smith, and Zongchao Jia
Binding Stoichiometry and Affinity of Fluorescent Dyes to Proteins in Different Structural States, Anna I. Sulatskaya, Olga I. Povarova, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov
Binding Stoichiometry and Affinity of Fluorescent Dyes to Proteins in Different Structural States, Anna I. Sulatskaya, Olga I. Povarova, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov
Applications of Bioinformatics and Experimental Methods to Intrinsic Disorder-based Protein-protein Interactions, Xiaolin Sun, William T. Jones, and Vladimir N. Uversky
Analysis of the Tau-Associated Proteome Reveals That Exchange of Hsp70 for Hsp90 Is Involved in Tau Degradation, Andrea D. Thompson, K. Matthew Scaglione, John Prensner, Anne T. Gillies, Arul Chinnaiyan, Henry L. Paulson, Umesh Jinwal, Chad A. Dickey, and Jason E. Gestwicki
Interactions Between The C-terminus of Kv1.5 and Kvβ Regulate Pyridine Nucleotide-Dependent Changes in Channel Gating, Srinicas M. Tipparaju, Xiao-Ping Li, Peter J. Kilfoil, Bin Xue, Vladimir N. Uversky, Aruni Bhatnagar, and Oleg A. Barski
Disordered Competitive Recruiter: Fast and Foldable, Vladimir N. Uversky
Intrinsically Disordered Proteins and Novel Strategies for Drug Discovery, Vladimir N. Uversky
Size-Exclusion Chromatography in Structural Analysis of Intrinsically Disordered Proteins, Vladimir N. Uversky
Size-exclusion Chromatography in Structural Analysis of Intrinsically Disordered Proteins, Vladimir N. Uversky
Multiparametric Analysis of Intrinsically Disordered Proteins: Looking at Intrinsic Disorder Through Compound Eyes, Vladimir N. Uversky and A. Keith Dunker
Intrinsically Disordered Proteins, Vladimir N. Uversky and A. Keith Dunker
Why are We Interested in the Unfolded Peptides and Proteins?, Vladimir N. Uversky and A. Keith Dunker
Protein Disorder and Human Genetic Disease, Vladimir N. Uversky, Lilia M. Iakoucheva, and A. Keith Dunker
Length-dependent Compaction of Intrinsically Disordered Proteins, Vladimir N. Uversky, Carlo Santambrogio, Stefania Brocca, and Rita Grandori
