Submissions from 2011
Intrinsically Disordered Proteins May Escape Unwanted Interactions Via Functional Misfolding, Vladimir N. Uversky
Multiparametric Approach in Analysis of Protein Structure and Unfolding-refolding Reaction, Vladimir N. Uversky
Multitude of Binding Modes Attainable by Intrinsically Disordered Proteins: a Portrait Gallery of Disorder-based Complexes, Vladimir N. Uversky
Systematic Analysis of Tropomodulin/tropomyosin Interactions Uncovers Fine-tuned Binding Specificity of Intrinsically Disordered Proteins, Vladimir N. Uversky, Samar P. Shah, Yulia Gritsyna, Sarah E. Hitchcock-DeGregori, and Alla S. Kostyukova
Abundance and Functional Roles of Intrinsic Disorder in Allergenic Proteins and Allergen Representative Peptides, Bin Xue, Daniel Soeria-Atmadja, Mats G. Gustafsson, Ulf Hammerling, A. Keith Dunker, and Vladimir N. Uversky
Do Viral Proteins Possess Unique Features?, Bin Xue, Robert W. Williams, Christopher J. Oldfield, Gerard Kian-Meng Goh, A. Keith Dunker, and Vladimir N. Uversky
Submissions from 2010
GM-CSF Upregulated in Rheumatoid Arthritis Reverses Cognitive Impairment and Amyloidosis in Alzheimer Mice, Tim D. Boyd, Steven P. Bennett, Takashi Mori, Nicholas Governatori, Melissa Runfeldt, Jaya Padmanabhan, Peter Neame, Inge Wefes, Juan Sanchez-Ramos, Gary W. Arendash, and Huntington Potter
Analysis of The Metabolites in Apical Area of Allium Cepa Roots by High Resolution NMR Spectroscopy Method, Arkady Yu. Budantsev, Vladimir N. Uversky, and Victor P. Kutyshenko
Functional Dissection of an Intrinsically Disordered Protein: Understanding The Roles of Different Domains of Knr4 Protein in Protein–protein Interactions, Adilia Dagkessamanskaia, Fabien Durand, Vladimir N. Uversky, Matteo Binda, Frédéric Lopez, Karim El Azzouzi, Jean Marie Francois, and Hélène Martin-Yken
Drugs for ‘Protein Clouds’: Targeting Intrinsically Disordered Transcription Factors, A. Keith Dunker and Vladimir N. Uversky
Oncogenic Partnerships: EWS-FLI1 Protein Interactions Initiate Key Pathways of Ewing's Sarcoma, Hayriye V. Erkizan, Vladimir N. Uversky, and Jeffrey A. Toretsky
Unique Physical Properties and Interactions of The Domains of Methylated DNA Binding Protein 2, Rajarshi P. Ghosh, Tatiana Nikitina, Rachel A. Horowitz-Scherer, Lila M. Gierasch, Vladimir N. Uversky, Patel Hitendra, Kristopher Hite, Jeffrey C. Hansen, and Christopher L. Woodcock
Protein Tandem Repeats – The More Perfect, The Less Structured, Julien Jordan, Bin Xue, Vladimir N. Uversky, and Andrey V. Kajava
Nanoimaging for Protein Misfolding Diseases, Yuri L. Lyubchenko, Bo-Hyun Kim, Alexey V. Krasnoslobodtse, and Junping Yu
Effects of Various Flavonoids on The α-synuclein Fibrillation Process, Xiaoyun Meng, Larissa A. Munishkina, Anthony L. Fink, and Vladimir N. Uversky
Human Herpesvirus 6, József Ongrádi, Valéria Kövesdi, and G. Péter Medveczky
Fluorescence Spectroscopy of Intrinsically Disordered Proteins, Eugene A. Permyakov and Vladimir N. Uversky
Analysis of Ca2+/Mg2+ Selectivity in α-lactalbumin and Ca2+-binding Lysozyme Reveals a Distinct Mg2+-specific Site in Lysozyme, Sergei E. Permyakov, Tatyana I. Khokhlova, Vladimir N. Uversky, and Eugene A. Permyakov
Proteomic Identification of Hsc70 as a Mediator of RGS9-2 Degradation by in Vivo Interactome Analysis, Ekaterina Posokhova, Vladimir N. Uversky, and Kirill A. Martemyanov
α-Synuclein and Metals, A. Santner and Vladimir N. Uversky
Fluorescence Quantum Yield of Thioflavin T in Rigid Isotropic Solution and Incorporated into The Amyloid Fibrils, Anna I. Sulatskaya, Alexander A. Maskevich, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov
N-terminal Domains of DELLA Proteins Are Intrinsically Unstructured in The Absence of Interaction with Gid1/gibberellic Acid Receptors, Xiaolin Sun, William T. Jones, Dawn Harvey, Patrick J. B. Edwards, Steven M. Pascale, Christopher Kirk, Thérèse Considine, David J. Sheerin, Jasna Rakonjac, Christopher J. Oldfield, Bin Xue, A. Keith Dunker, and Vladimir N. Uversky
The Protein Kingdom Extended: Ordered and Intrinsically Disordered Proteins, Their Folding, Supramolecular Complex Formation, and Aggregation, Konstantin K. Turoverov, Irina M. Kuznetsova, and Vladimir N. Uversky
Analyzing Intrinsically Disordered Proteins by Size Exclusion Chromatography, Vladimir N. Uversky
Conformational Behavior of Intrinsically Disordered Proteins: Effects of Strong Denaturants, Temperature, PH, Counterions, and Macromolecular Crowding, Vladimir N. Uversky
Mysterious Oligomerization of The Amyloidogenic Proteins, Vladimir N. Uversky
Seven Lessons from One IDP Structural Analysis, Vladimir N. Uversky
Targeting Intrinsically Disordered Proteins in Neurodegenerative and Protein Dysfunction Diseases: Another Illustration of The D2 Concept, Vladimir N. Uversky
Large-scale Identification of Intrinsically Disordered Proteins, Vladimir N. Uversky, Marc S. Cortese, Peter Tompa, Veronika Csizmok, and A. Keith Dunker
Understanding Protein Non-folding, Vladimir N. Uversky and A. Keith Dunker
PONDR-FIT: A Meta-predictor of Intrinsically Disordered Amino Acids, Bin Xue, Roland L. Dunbrack, Robert W. Williams, A. Keith Dunker, and Vladimir N. Uversky
Retro-MoRFs: Identifying Protein Binding Sites by Normal and Reverse Alignment and Intrinsic Disorder Prediction, Bin Xue, A. Keith Dunker, and Vladimir N. Uversky
SPA: Short Peptide Analyzer of Intrinsic Disorder Status of Short Peptides, Bin Xue, Wei-Lun Hsu, Jun-Ho Lee, Hua Lu, A. Keith Dunker, and Vladimir N. Uversky
Archaic Chaos: Intrinsically Disordered Proteins in Archaea, Bin Xue, Robert W. Williams, Christopher J. Oldfield, A. Keith Dunker, and Vladimir N. Uversky
Viral Disorder Or Disordered Viruses: Do Viral Proteins Possess Unique Features?, Bin Xue, Robert W. Williams, Christopher J. Oldfield, Gerard Kian-Meng Goh, A. Keith Dunker, and Vladimir N. Uversky
Share on Role of an Expanded Inositol Transporter Repertoire in Cryptococcus Neoformans Sexual Reproduction and Virulence, Chaoyang Xue, Tongbao Liu, Lydia Chen, Wenjun Li, Iris Liu, James W. Kronstad, Andreas Seyfang, and Joseph Heitman
A Bimodal Distribution of Two Distinct Categories of Intrinsically Disordered Structures with Separate Functions in FG Nucleoporins, Justin Yamada, Joshua L. Philips, Samir Patel, Gabriel Goldfien, Alison Calestagne-Morelli, Hans Huang, Ryan Reza, Justin Acheson, Viswanathan V. Krishnan, Shawn Newsam, Ajay Gopinathan, Edmond Y. Lau, Michael E. Colvin, Vladimir N. Uversky, and Michael F. Rexach
3, 4-dihydroxyphenylacetic Acid (DOPAC) Impairs α-synuclein Interaction with Lipids, Wenbo Zhou, Chunmei Long, Anthony L. Fink, and Vladimir N. Uversky
Calbindin-d28k Acts as a Calcium-dependent Chaperone Suppressing α-synuclein Fibrillation in Vitro, Wenbo Zhou, Chunmei Long, Anthony L. Fink, and Vladimir N. Uversky
Methionine Oxidation Stabilizes Non-toxic Oligomers of α-synuclein Through Strengthening The Auto-inhibitory Intra-molecular Long-range Interactions, Wenbo Zhou, Chunmei Long, Stephen H. Reaney, Donato A. Do Monte, Anthony L. Fink, and Vladimir N. Uversky
Submissions from 2009
The C Type Natriuretic Peptide Receptor Tethers AHNAK1 at the Plasma Membrane to Potentiate Arachidonic Acid-Induced Calcium Mobilization, Abdel A. Alli and William R. Gower Jr.
Caffeine Reverses Cognitive Impairment and Decreases Brain Amyloid-β Levels in Aged Alzheimer's Disease Mice, Gary W. Arendash, Takashi Mori, Chuanhai Cao, Malgorzata Mamcarz, Melissa Runfeldt, Alexander Dickson, Kavon Rezai-Zadeh, Jun Tan, Bruce A. Citron, Xiaoyang Lin, Valentina Echeverria, and Huntington Potter
Order Propensity of an Intrinsically Disordered Protein, The Cyclin-dependent-kinase Inhibitor Sic1, Stefania Brocca, Mária Šamalíková, Vladimir N. Uversky, Marina Lotti, Lilia Alberghina, and Rita Grandori
Cryoenzymology: Enzyme Action in Slow Motion, Ben M. Dunn and Vladimir N. Uversky
Anthony L. Fink (1943-2008): Scientist, Teacher and Artist, Olöf Einarsdóttir and Vladimir N. Uversky
Characterization of Intrinsically Disordered Proteins with Electrospray Ionization Mass Spectrometry: Conformational Heterogeneity of α-synuclein, Agya K. Frimpong, Rinat R. Abzalimov, Vladimir N. Uversky, and Igor A. Kaltashov
Polycation-induced Oligomerization and Accelerated Fibrillation of Human α-synuclein in Vitro, John Goers, Vladimir N. Uversky, and Anthony L. Fink
Acid Denaturation and Anion-induced Folding of Globular Proteins: Multitude of Equilibrium Partially Folded Intermediates, Junichi Goto and Vladimir N. Uversky
Navigational Predictors in Determining the Necessity for Collateral Ligament Release in Total Knee Replacement, S. Hakki, S. Coleman, V. J. Bilotta, and A. Hakki
Predicting Intrinsic Disorder in Proteins: an Overview, Bo He, Yunlong Liu, Vladimir N. Uversky, and A. Keith Dunker
Intrinsic Disorder in Viral Proteins Genome-linked: Experimental and Predictive Analyses, Eugénie Hébrard, Yannick Bessin, Thierry Michon, Sonia Longhi, Vladimir N. Uversky, François Delalande, Alain Van Dorsselaer, Pedro Romero, Jocelyn Walter, Nathalie Declerck, and Denis Fargette
Smoking and Parkinson's Disease: Does Nicotine Affect α-synuclein Fibrillation?, Dong-Pyo Hong, Anthony L. Fink, and Vladimir N. Uversky
Phenotypic and Gene Expression Changes among Clonal Type I Strains of Toxoplasma gondii, Asis Khan, Michael S. Behnke, Ildiko R. Dunay, Michael W. White, and L. David Sibley
Protein Intrinsic Disorder and Influenza Virulence: The 1918 H1N1 and H5N1 Viruses, Gerard Kian-Meng Goh, A. Keith Dunker, and Vladimir N. Uversky
Solution Structure and Dynamics of The Chimeric SH3 Domains, SHH- and ShA-“Bergeracs”, Victor P. Kutyshenko, Dmitry Prokhorov, Maria A. Timchenko, Yuri A. Kudrevatykh, Liubov V. Gushchina, Vladimir S. Khristroforon, Liubov V. Gushchina, Vladimir V. Filimonov, and Vladimir N. Uversky
Exploring The Molecular Design of Protein Interaction Sites with Molecular Dynamics Simulations and Free Energy Calculations, Shide Liang, Liwei Li, Wei-Lun Hsu, Meaghan N. Pilcher, Vladimir N. Uversky, Yaoqi Zhou, A. Keith Dunker, and Samy O. Meroueh
Molecular Mechanisms Underlying The Flavonoid-induced Inhibition of α-synuclein Fibrillation, Xiaoyun Meng, Larissa A. Munishkina, Anthony L. Fink, and Vladimir N. Uversky
Substance P Increases Cell-Surface Expression of CD74 (Receptor for Macrophage Migration Inhibitory Factor): In Vivo Biotinylation of Urothelial Cell-Surface Proteins, Katherine L. Meyer-Siegler, Shen-Ling Xia, and Pedro L. Vera
Unfoldomics of Human Genetic Diseases: Illustrative Examples of Ordered and Intrinsically Disordered Members of The Human Diseasome, Uros Midic, A. Keith Dunker, Zoran Obradovic, and Vladimir N. Uversky
Protein Disorder in The Human Diseasome: Unfoldomics of Human Genetic Diseases, Uros Midic, Christopher J. Oldfield, A. Keith Dunker, Zoran Obradovic, and Vladimir N. Uversky
Influence of Sequence Changes and Environment on Intrinsically Disordered Proteins, Amrita Mohan, Vladimir N. Uversky, and Predrag Radivojac
Accelerated Fibrillation of α-synuclein Induced by The Combined Action of Macromolecular Crowding and Factors Inducing Partial Folding, Larissa A. Munishkina, Anthony L. Fink, and Vladimir N. Uversky
Metal-controlled Interdomain Cooperativity in Parvalbumins, Sergei E. Permyakov, Anush G. Bakunts, Maria E. Permyakova, Alexander I. Denesyuk, Vladimir N. Uversky, and Eugene A. Permyakov
Mechanisms and Consequences of Protein Aggregation: The Role of Folding Intermediates, Sangita Seshadri, Keith A. Oberg, and Vladimir N. Uversky
Do Viral Proteins Possess Unique Biophysical Features?, Nobuhiko Tokuriki; Christopher J. Oldfield; Vladimir N. Uversky; Igor N. Berezovsky; and Dan S, Tawfik
Close Encounters of The Third Kind: Disordered Domains and The Interactions of Proteins, Peter Tompa, Monika Fuxreiter, Christopher J. Oldfield, Istvan Simon, A. Keith Dunker, and Vladimir N. Uversky
Intrinsically Disordered Proteins and Their Environment: Effects of Strong Denaturants, Temperature, pH, Counter Ions, Membranes, Binding Partners, Osmolytes, and Macromolecular Crowding, Vladimir N. Uversky
Intrinsic Disorder in Proteins Associated with Neurodegenerative Diseases, Vladimir N. Uversky
Neuropathology and Neurochemistry of Parkinson’s Disease: The Never-ending Story Or The Story with No Beginning?, Vladimir N. Uversky
The Mysterious Unfoldome: Structureless, Underappreciated, Yet Vital Part of Any Given Proteome, Vladimir N. Uversky
Biophysics of Parkinson's Disease: Structure and Aggregation of α- Synuclein, Vladimir N. Uversky and David Eliezer
Intrinsically Disordered Proteins and Their Recognition Functions, Vladimir N. Uversky, Monika Fuxreiter, Christopher J. Oldfield, A. Keith Dunker, and Peter Tompa
Unfoldomics of Human Diseases: Linking Protein Intrinsic Disorder with Diseases, Vladimir N. Uversky, Christopher J. Oldfield, Uros Midic, Hongbo Xie, Bin Xue, Slobodan Vucetic, Lilia M. Iakoucheva, Zoran Obradovic, and A. Keith Dunker
Analysis of Structured and Intrinsically Disordered Regions of Transmembrane Proteins, Bin Xue, Liwei Li, Samy O. Meroueh, Vladimir N. Uversky, and A. Keith Dunker
CDF It All: Consensus Prediction of Intrinsically Disordered Proteins Based on Various Cumulative Distribution Functions, Bin Xue, Christopher J. Oldfield, A. Keith Dunker, and Vladimir N. Uversky
At Low Concentrations, 3,4-dihydroxyphenylacetic Acid (DOPAC) Binds Non-covalently to α-synuclein and Prevents Its Fibrillation, Wenbo Zhou, Amy Gallagher, Dong-Pyo Hong, Chunmei Long, Anthony L. Fink, and Vladimir N. Uversky
Submissions from 2008
Interaction of Yersinia pestis Virulence Factors with IL-1R/TLR Recognition System, Vyacheslav M. Abramov, Valentin S. Khlebnikov, Anatoly M. Vasiliev, Igor V. Kosarev, Raisa N. Vasilenko, Nataly L. Kulikova, Vladimir L. Motin, Georgy B. Smirnov, Valentin I. Evstigneev, Nicolay N. Karkischenko, Vladimir N. Uversky, and Robert R. Brubaker
Top-idp-scale: A New Amino Acid Scale Measuring Propensity for Intrinsic Disorder, Andrew Campen, Ryan M. Williams, Celeste J. Brown, Jingwei Meng, Vladimir N. Uversky, and A. Keith Dunker
Suppression of Dendritic Cell Activation by Anthrax Lethal Toxin and Edema Toxin Depends on Multiple Factors Including Cell Source, Stimulus Used, and Function Tested, Ping-Jen Chou, Catherine A. Newton, Izabella Perkins, Herman Friedman, and Thomas W. Klein
Intrinsic Disorder in Scaffold Proteins: Getting More from Less, Marc S. Cortese, Vladimir N. Uversky, and A. Keith Dunker
Prevalence of Intrinsic Disorder in The Intracellular Region of Human Single-pass Type I Proteins: The Case of The Notch Ligand Delta-4, Alfredo De Biasio, Corrado Guarnaccia, Matija Popovic, Vladimir N. Uversky, Alessandro Pintar, and Sándor Pongor
The Unfoldomics Decade: an Update on Intrinsically Disordered Proteins, A. Keith Dunker, Christopher J. Oldfield, Jingwei Meng, Pedro Romero, Jack Y. Yang, Jessica Walton Chen, Vladimir Vacic, Zoran Obradovic, and Vladimir N. Uversky
Function and Structure of Inherently Disordered Proteins, A. Keith Dunker, Israel Silman, Vladimir N. Uversky, and Joel Sussman
Signal Transduction Via Unstructured Protein Conduits, A. Keith Dunker and Vladimir N. Uversky
Structure–function Analysis of Knr4/Smi1, a Newly Member of Intrinsically Disordered Proteins Family, Indispensable in The Absence of a Functional PKC1–SLT2 Pathway in Saccharomyces Cerevisiae, Fabien Durand, Adilia Dagkessamanskaia, Hélène Martin-Yken, Marc Graille, Herman Van Tilbeurgh, Vladimir N. Uversky, and Jean Marie Francois
Malleable Machines Take Shape in Eukaryotic Transcriptional Regulation, Monika Fuxreiter, Peter Tompa, István Simon, Vladimir N. Uversky, Jeffrey C. Hansen, and Francisco J. Asturias
Protein Intrinsic Disorder Toolbox for Comparative Analysis of Viral Proteins, Gerard Kian-Meng Goh, A. Keith Dunker, and Vladimir N. Uversky
Structural Characteristics of α-synuclein Oligomers Stabilized by The Flavonoid Baicalein, Dong-Pyo Hong, Anthony L. Fink, and Vladimir N. Uversky
Effect of Methionine Oxidation on The Structural Properties, Conformational Stability, and Aggregation of Immunoglobulin Light Chain LEN, Dongmei Hu, Zhijie Qin, Bin Xue, Anthony L. Fink, and Vladimir N. Uversky
A Comparative Analysis of Viral Matrix Proteins Using Disorder Predictors, Gerard Kian-Meng Goh, A. Keith Dunker, and Vladimir N. Uversky
The Effect of Membranes on The In Vitro Fibrillation of an Amyloidogenic Light-chain Variable-domain SMA, Xiaoyun Meng, Anthony L. Fink, and Vladimir N. Uversky
Intrinsic Disorder in Pathogenic and Non-pathogenic Microbes: Discovering and Analyzing The Unfoldomes of Early-branching Eukaryotes, Amrita Mohan, William J. Sullivan Jr, Predrag Radivojac, A. Keith Dunker, and Vladimir N. Uversky
Guiding Protein Aggregation with Macromolecular Crowding, Larissa A. Munishkina, Atta Ahmad, Anthony L. Fink, and Vladimir N. Uversky
Concerted Action of Metals and Macromolecular Crowding on The Fibrillation of α-synuclein, Larissa A. Munishkina, Anthony L. Fink, and Vladimir N. Uversky
Flexible Nets: Disorder and Induced Fit in The Associations of P53 and 14-3-3 with Their Partners, Christopher J. Oldfield, Jingwei Meng, Jack Y. Yang, Mary Qu Yang, Vladimir N. Uversky, and A. Keith Dunker
Protein Disorder Is Positively Correlated with Gene Expression In Escherichia Coli, Oleg Paliy, Shawn M. Gargac, Yugong Cheng, Vladimir N. Uversky, and A. Keith Dunker
Apo-parvalbumin as an Intrinsically Disordered Protein, Sergei E. Permyakov, Anush G. Bakunts, Alexander I. Denesyuk, Ekaterina L. Knyazeva, Vladimir N. Uversky, and Eugene A. Permyakov
Dynamics of Oligomer Formation by Denatured Carbonic Anhydrase II, Dmitry A. Prokhorov, Maria A. Timchenko, Vladimir N. Uversky, Vladimir S. Khristoforov, Hiroshi Kihara, Kazumoto Kimura, and Victor P. Kutyshenko
Potato Virus A Genome-linked Protein Vpg is an Intrinsically Disordered Molten Globule-like Protein with a Hydrophobic Core, Kimmo I. Rantalainen, Vladimir N. Uversky, Perttu Permi, Nisse Kalkkinen, A. Keith Dunker, and Kristiina Mäkinen
Short Linear Motifs Recognized by SH2, SH3 and Ser/thr Kinase Domains are Conserved in Disordered Protein Regions, Siyun Ren, Vladimir N. Uversky, Zhengjun Chen, A. Keith Dunker, and Zoran Obradovic
