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Submissions from 2021

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Targeting Autophagy in Ischemic Stroke: From Molecular Mechanisms to Clinical Therapeutics, Amir Ajoolabady, Shuyi Wang, Guido Kroemer, Josef M. Penninger, Vladimir N. Uversky, Domenico Pratico, Nils Henninger, Russel J. Reiter, Askiel Bruno, Kaumudi Joshipura, Hamid Aslkhodapasandhokmabad, Daniel J. Klionsky, and Jun Ren

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On the Prevalence and Potential Functionality of an Intrinsic Disorder in the MERS-CoV Proteome, Manal A. Alshehri, Manee M. Manee, Fahad H. Alqahtani, Badr M. Al-Shomrani, and Vladimir N. Uversky

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Chemical Synthesis of Peptidoglycan Mimetic–disaccharide-tetrapeptide Conjugate and Its Hydrolysis by Bacteriophage T5, RB43 and RB49 L-alanyl-D-glutamate Peptidases, Viatcheslav Azev, Alexey Chulin, Maxim Molchanov, Dmitry Prokhorov, Galina Mikoulinskaia, Vladimir N. Uversky, and Viktor Kutyshenko

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Dancing with Trojan Horses: an Interplay Between the Extracellular Vesicles and Viruses, Raied A. Badierah, Vladimir N. Uversky, and Elrashdy M. Redwan

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Secondary Structure Dependence of Amyloid-β(1–40) on Simulation Techniques and Force Field Parameters, Murat Caliskan, Sunay Y. Mandaci, Vladimir N. Uversky, and Orkid Coskuner-Weber

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Phenotypic Suppression Caused by Resonance with Light-dark Cycles Indicates the Presence of a 24-hours Oscillator in Yeast and Suggests a New Role of Intrinsically Disordered Protein Regions as Internal Mediators, Ilaria Camponeschi, Achille Damasco, Vladimir N. Uversky, Alessandro Giuliani, and Michele M. Bianchi

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Small Heat Shock Protein 22 kDa Can Modulate the Aggregation and Liquid–liquid Phase Separation Behavior of Tau, April L. Darling, Jan Dahrendorff, Stefan G. Creodore, Chad A. Dickey, Laura J. Blair, and Vladimir N. Uversky

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Effects of Different Solutes on the Physical Chemical Properties of Aqueous Solutions via Rearrangement of Hydrogen Bonds in Water, Nuno da Silva, Luisa A. Ferreira, Alexander I. Belgovskiy, Pedro P. Madeira, José A. Teixeira, Elizabeth K. Mann, J. Adin Mann, William V. Meyer, Anthony E. Smart, Vladimir Y. Chernyak, Vladimir N. Uversky, and Boris Y. Zaslavsky

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Structural Leitmotif and Functional Variations of the Structural Catalytic Core in (chymo)trypsin-like Serine/cysteine Fold Proteinases, Alexander I. Denesyuk, Sergei E. Permyakov, Mark S. Johnson, Eugene A. Permyakov, Vladimir N. Uversky, and Konstantin Denessiouk

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Structural Facets of POU2F1 in Light of the Functional Annotations and Sequence-structure Patterns, Ashmita Dey, Sagnik Sen, Vladimir N. Uversky, and Ujjwal Maulik

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Photo-dependent Membrane-less Organelles Formed from Plant PhyB and PIF6 Proteins in Mammalian Cells, Alexander V. Fonin, Iuliia A. Antifeeva, Olesya G. Shpironok, Olesya V. Stepanenko, Sergey A. Silonov, Olga V. Stepanenko, Ivan E. Antifeev, Anna E. Romanovich, Irina M. Kuznetsova, Jeong-Il Kim, Vladimir N. Uversky, and Konstantin K. Turoverov

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Understanding COVID-19 via Comparative Analysis of Dark Proteomes of SARS-CoV-2, Human SARS and Bat SARS-like Coronaviruses, Rajanish Giri, Taniya Bhardwaj, Meenakshi Shegane, Bhuvaneshwari R. Gehi, Prateek Kumar, Kundlik Gadhave, Christopher J. Oldfield, and Vladimir N. Uversky

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Tudor Staphylococcal Nuclease is a Docking Platform for Stress Granule Components and is Essential for SnRK1 Activation in Arabidopsis, Emilio Gutierrez-Beltran, Pernilla H. Elander, Kerstin Dalman, Guy W. Dayhoff, Panagiotis N. Moschou, Vladimir N. Uversky, Jose L. Crespo, and Peter V. Bozhkov

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On the Role of Normal Aging Processes in the Onset and Pathogenesis of Diseases Associated with the Abnormal Accumulation of Protein Aggregates, Nikolay S. Ilyinsky, Semen V. Nesterov, Elizaveta I. Shestoperova, Alexander V. Fonin, Vladimir N. Uversky, and Valentin I. Gordeliy

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Comprehensive Intrinsic Disorder Analysis of 6108 Viral Proteomes: From the Extent of Intrinsic Disorder Penetrance to Functional Annotation of Disordered Viral Proteins, Naveen Kumar, Rahul Kaushik, Chandana Tennakoon, Vladimir N. Uversky, Sonia Longhi, Kam Y. Zhang, and Sandeep Bhatia

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Comparative Analysis of the Active Sites of Orthologous Endolysins of the Escherichia Lytic Bacteriophages T5, RB43, and RB49, Victor P. Kutyshenko, Dmitry A. Prokhorov, Galina V. Mikoulinskaia, Nikolai V. Molochkov, Alexander Y. Yegorov, Svetlana I. Paskevich, and Vladimir N. Uversky

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In Vitro N-Terminal Acetylation of Bacterially Expressed Parvalbumins by N-Terminal Acetyltransferases from Escherichia Coli, Yulia S. Lapteva, Alisa A. Vologzhannikova, Andrey S. Sokolov, Ramis G. Ismailov, Vladimir N. Uversky, and Sergei E. Permyakov

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The Coxiella Burnetii QpH1 Plasmid Is a Virulence Factor for Colonizing Bone Marrow-Derived Murine Macrophages, Shengdong Luo, Shanshan Lu, Huahao Fan, Zeliang Chen, Zhihui Sun, Yan Hu, Ruisheng Li, Xiaoping An, Vladimir N. Uversky, Yigang Tong, and Lihua Song

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Prevalence and Functionality of Intrinsic Disorder in Human FG-nucleoporins, Denzelle Lee Lyngdoh, Niharika Nag, Vladimir N. Uversky, and Timir Tripathi

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Natural Resources to Control COVID-19: Could Lactoferrin Amend SARS-CoV-2 Infectivity?, Ehab H. Mattar, Fatma Elrashdy, Hussein A. Almehdar, Vladimir N. Uversky, and Elrashdy M. Redwan

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Simple and Efficient Protocol for Immunoglobulin Y Purification from Chicken Egg Yolk, Elrashdy M. Redwan, Abdullah A. Aljadawi, and Vladimir N. Uversky

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Understanding Structural Malleability of the SARS-CoV-2 Proteins and their Relation to the Comorbidities, Sagnik Sen, Ashmita Dey, Sanghamitra Bandyopadhyay, Ujjwal Maulik, and Vladimir Uversky

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Questions Concerning the Proximal Origin of SARS-CoV-2, Murat Seyran, Damiano Pizzol, Parise Adadi, Tarek M. El-Aziz, Sk. Sarif Hassan, Antonio Soares, Ramesh Kandimalla, Kenneth Lundstrom, Murtaza Tambuwala, Alaa A. Aljabali, Amos Lal, Gajendra K. Azad, Pabitra P. Choudhury, Vladimir N. Uversky, Samendra P. Sherchan, Bruce D. Uhal, Nima Rezaei, and Adam M. Brufsky

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Baicalein Inhibits Heparin-induced Tau Aggregation by Initializing Non-toxic Tau Oligomer Formation, Shweta Kishor Sonawane, Vladimir N. Uversky, and Subashchandrabose Chinnathambi

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Functional Characterization of an Unknown Soybean Intrinsically Disordered Protein in Vitro and in Escherichia coli, Fangmei Tan, Nan Sun, Linsong Zhang, Jiahui Wu, Shifeng Xiao, Qiulong Tan, Vladimir N. Uversky, and Yun Liu

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Biomolecules from Different Angles, Vladimir N. Uversky

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On the Irrationality of Rational Design of an HIV Vaccine in Light of Protein Intrinsic Disorder, Vladimir N. Uversky

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Recent Developments in the Field of Intrinsically Disordered Proteins: Intrinsic Disorder–Based Emergence in Cellular Biology in Light of the Physiological and Pathological Liquid–Liquid Phase Transitions, Vladimir N. Uversky

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Multifunctionality and Intrinsic Disorder of Royal Jelly Proteome, Vladimir N. Uversky, Abdulgader H. Albar, Rizwan H. Khan, and Elrashdy M. Redwan

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Severe Acute Respiratory Syndrome Coronavirus 2 Infection Reaches the Human Nervous System: How?, Vladimir N. Uversky, Fatma Elrashdy, Abdullah Aljadawi, Syed Moasfar Ali, Rizwan Hasan Khan, and Elrashdy M. Redwan

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Networks of Networks: An Essay on Multi-Level Biological Organization, Vladimir N. Uversky and Alessandro Giuliani

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Mobility and Disorder in Antibody and Antigen Binding Sites Do Not Prevent Immunochemical Recognition, Vladimir N. Uversky and Marc H. Regenmortel

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Bioinformatics Analysis of Correlation Between Protein Function and Intrinsic Disorder, Goran Vinterhalter, Jovana J. Kovačević, Vladimir N. Uversky, and Gordana M. Pavlović-Lažetić

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IDPology of the Living Cell: Intrinsic Disorder in the Subcellular Compartments of the Human Cell, Bi Zhao, Akila Katuwawala, Vladimir N. Uversky, and Lukasz Kurgan

Submissions from 2020

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S-layer Protein 2 of Lactobacillus crispatus 2029, Its Structural and Immunomodulatory Characteristics and Roles in Protective Potential of the Whole Bacteria against Foodborne Pathogens, Vyacheslav M. Abramov, Igor V. Kosarev, Tatiana V. Priputnevich, Andrey V. Machulin, Valentin S. Khlebnikov, Sergey Yu. Pchelintsev, Raisa N. Vasilenko, Vadim K. Sakulin, Natalia E. Suzina, Irina O. Chikileva, Evgenia I. Derysheva, Vyacheslav G. Melnikov, Ilya N. Nikonov, Vladimir A. Samoilenko, Eduard E. Svetoch, Gennady T. Sukhikh, Vladimir N. Uversky, and Andrey V. Karlyshev

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Bacteriostatic and Bactericidal Activities of Camel Lactoferrins Against Salmonella enterica Serovar Typhi, Hussein A. Almehdar, Nawal Abd El-Baky, Abdulqader A. Alhaider, Saud A. Almuhaideb, Abdullah A. Alhaider, Raed S. Albiheyri, Vladimir N. Uversky, and Elrashdy M. Redwan

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Japanese Encephalitis Virus – Exploring the Dark Proteome and Disorder–function Paradigm, Taniya Bhardwaj, Kumar Udit Saumya, Prateek Kumar, Nitin Sharma, Kundlik Gadhave, Vladimir N. Uversky, and Rajanish Giri

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Granulins Modulate Liquid–liquid Phase Separation and Aggregation of the Prion-like C-terminal Domain of the Neurodegeneration-associated Protein TDP-43, Anukool A. Bhopatkar, Vladimir N. Uversky, and Vijayaraghavan Rangachari

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Intrinsic Disorder in Human Proteins Encoded by Core Duplicon Gene Families, Nathan W. Bibber, Cornelia Haerle, Roy Khalife, Guy W. II, and Vladimir N. Uversky

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Chemical Complementarity Between Immune Receptor CDR3s and IDH1 Mutants Correlates with Increased Survival for Lower Grade Glioma, Boris I. Chobrutskiy, Michelle Yeagley, Price Tipping, Saif Zaman, Andrea Diviney, Dhruv N. Patel, Shayan Falasiri, Vladimir N. Uversky, and George Blanck

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RELT Stains Prominently in B-cell Lymphomas and Binds the Hematopoietic Transcription Factor MDFIC, John K. Cusick, Yasmeen Alhomsy, Stephanie Wong, George Talbott, Vladimir N. Uversky, Cara Hart, Nazila Hejazi, Aaron T. Jacobs, and Yihui Shi

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Intrinsic Disorder in Protein Sense-antisense Recognition, Guy W. Dayhoff, Marc H. Regenmortel, and Vladimir N. Uversky

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NBCZone: Universal Three-dimensional Construction of Eleven Amino Acids near the Catalytic Nucleophile and Base in the Superfamily of (chymo)trypsin-like Serine Fold Proteases, Alexander I. Denesyuk, Mark S. Johnson, Outi M.H. Salo-Ahen, Vladimir N. Uversky, and Konstantin Denessiouk

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Expanding the Understanding of the Heterogeneous Nature of Melanoma with Bioinformatics and Disorder-based Proteomics, Mak B. Djulbegovic and Vladimir N. Uversky

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DeepAdd: Protein Function Prediction from K-mer Embedding and Additional Features, Zhihua Du, Yufeng He, Jianqiang Li, and Vladimir N. Uversky

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Why COVID-19 Transmission Is More Efficient and Aggressive Than Viral Transmission in Previous Coronavirus Epidemics?, Fatma Elrashdy, Elrashdy M. Redwan, and Vladimir N. Uversky

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The Dark Side of Alzheimer’s Disease: Unstructured Biology of Proteins from the Amyloid Cascade Signaling Pathway, Kundlik Gadhave, Bhuvaneshwari R. Gehi, Prateek Kumar, Bin Xue, Vladimir N. Uversky, and Rajanish Giri

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Nipah Shell Disorder, Modes of Infection, and Virulence, Gerard Kian-Meng Goh, A. Keith Dunker, James A. Foster, and Vladimir N. Uversky

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Lung Cancer Cells Survive Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Exposure through Upregulation of Cholesterol Synthesis, Mark C. Howell, Ryan Green, Roukiah Khalil, Elspeth Foran, Waise Quarni, Rajesh Nair, Stanley Stevens, Aleksandr Grinchuk, Andrew Hanna, Shyam Mohapatra, and Subhra Mohapatra

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Deciphering the Structural Intricacy in Virulence Effectors for Proton-motive Force Mediated Unfolding in Type-III Protein Secretion, Basavraj Khanppnavar, Anupam Roy, Kausik Chandra, Vladimir N. Uversky, Nakul Chandra Maiti, and Saumen Datta

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Folding and Structural Polymorphism of P53 C-terminal Domain: One Peptide with Many Conformations, Amit Kumar, Prateek Kumar, Shobha Kumari, Vladimir N. Uversky, and Rajanish Giri

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Targeting the NTPase Site of Zika Virus NS3 Helicase for Inhibitor Discovery, Deepak Kumar, Murali Aarthy, Prateek Kumar, Sanjeev Kumar Singh, Vladimir N. Uversky, and Rajanish Giri

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Understanding the Penetrance of Intrinsic Protein Disorder in Rotavirus Proteome, Deepak Kumar, Ankur Singh, Prateek Kumar, Vladimir N. Uversky, C. Durga Rao, and Rajanish Giri

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On the Roles of Calcium and Zinc Ions in the Formation of a Catalytically Active Form of the Metalloenzyme, L-alanyl-d-glutamate Peptidase of the Bacteriophage T5 (EndoT5), Victor P. Kutyshenko, Galina V. Mikoulinskaia, Dmitry A. Prokhorov, Nikolai V. Molochkov, Alexander Y. Yegorov, and Vladimir N. Uversky

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Can a Retro-polypeptide Fold into a Globule?, Victor P. Kutyshenko, Mars G. Sharapov, and Vladimir N. Uversky

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The Dual PI3Kδ/CK1ε Inhibitor Umbralisib Exhibits Unique Immunomodulatory Effects on CLL T Cells, Kamira Maharaj, John J. Powers, Alex Achille, Melanie Mediavilla-Varela, Wael Gamal, Karen L. Burger, Renee Fonseca, Kun Jiang, Hari P. Miskin, Dave Maryanski, Andrii Monastyrskyi, Derek R. Duckett, William R. Roush, John L. Cleveland, Eva Sahakian, and Javier Pinilla-Ibarz

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Loops Linking Secondary Structure Elements Affect the Stability of the Molten Globule Intermediate State of Apomyoglobin, Maria A. Majorina, Vitaly A. Balobanov, Vladimir N. Uversky, and Bogdan S. Melnik

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Epitope Region Identification Challenges of Intrinsically Disordered Proteins in Neurodegenerative Diseases: Secondary Structure Dependence of Α-synuclein on Simulation Techniques and Force Field Parameters, Sunay Y. Mandaci, Murat Caliskan, M. Furkan Sariaslan, Vladimir N. Uversky, and Orkid Coskuner-Weber

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Liquid-liquid Phase Separation and Fibrillation of the Prion Protein Modulated by a High-affinity DNA Aptamer, Carolina O. Matos, Yulli M. Passos, Mariana J. Amaral, Bruno Macedo, Matheus H. Tempone, Ohanna C. Bezerra, Milton O. Moraes, Marcius S. Almeida, Gerald Weber, Sotiris Missailidis, Jerson L. Silva, Vladimir N. Uversky, Anderson S. Pinheiro, and Yraima Cordeiro

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The Exquisite Structural Biophysics of the Golgi Reassembly and Stacking Proteins, Luís F.S. Mendes, Natália A. Fontana, S. Thirupathi Reddy, Vladimir N. Uversky, and Antonio J. Costa-Filho

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Proceedings of the 2019 NanoFlorida International Conference Held at the University of South Florida, Tampa, FL, Shyam S. Mohapatra, Robert D. Frisina, Subhra Mohapatra, Mandip Singh, and Manh-Huong Phan

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Codon Selection Reduces GC Content Bias in Nucleic Acids Encoding for Intrinsically Disordered Proteins, Christopher J. Oldfield, Zhenling Peng, Vladimir N. Uversky, and Lukasz Kurgan

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Analyzing Aggregation Propensities of Clinically Relevant PTEN Mutants: a New Culprit in Pathogenesis of Cancer and Other PTENopathies, Emily Palumbo, Bi Zhao, Bin Xue, Vladimir N. Uversky, and Vrushank Davé

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Mouse S100G Protein Exhibits Properties Characteristic of a Calcium Sensor, Sergei E. Permyakov, Elena N. Yundina, Alexei S. Kazakov, Maria E. Permyakova, Vladimir N. Uversky, and Eugene A. Permyakov

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Biophysical Characterization of Intrinsically Disordered Human Golgi Matrix Protein GRASP65, S. Thirupathi Reddy, Vladimir N. Uversky, and Antonio J. Costa-Filho

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Nucleation-dependent Amyloid Fibrillation of Human GRASP55 in Aqueous Solution, S. Thirupathi Reddy, Vladimir N. Uversky, and Antonio Jose Costa-Filho

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Disorder in Milk Proteins: Adipophilin and TIP47, Important Constituents of the Milk Fat Globule Membrane, Elrashdy M. Redwan, Saleh A. Alkarim, Amr A. El-Hanafy, Yasser M. Saad, Hussein A. Almehdar, and Vladimir N. Uversky

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Comprehensive Analysis of the Molecular Docking of Small Molecule Inhibitors to the Aβ1–40 Peptide and Its Osaka-mutant: Insights into the Molecular Mechanisms of Aβ-peptide Inhibition, Parveen Salahuddin, Rizwan Hasan Khan, and Vladimir N. Uversky

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Folding Perspectives of an Intrinsically Disordered Transactivation Domain and Its Single Mutation Breaking the Folding Propensity, Nitin Sharma, Alexander V. Fonin, Olesya G. Shpironok, Sergey A. Silonov, Konstantin K. Turoverov, Vladimir N. Uversky, Irina M. Kuznetsova, and Rajanish Giri

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Single-cell RNA-Seq: a Next Generation Sequencing Tool for a High-resolution View of the Individual Cell, Kevin Stevenson and Vladimir N. Uversky

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Interfacial Tension and Mechanism of Liquid–liquid Phase Separation in Aqueous Media, Amber R. Titus, Luisa A. Ferreira, Alexander I. Belgovskiy, Edgar E. Kooijman, Elizabeth K. Mann, J. Adin Mann Jr, William V. Meyer, Anthony E. Smart, Vladimir N. Uversky, and Boris Y. Zaslavsky

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Functions of Short Lifetime Biological Structures at Large: the Case of Intrinsically Disordered Proteins, Vladimir N. Uversky

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New Technologies to Analyse Protein Function: An Intrinsic Disorder Perspective, Vladimir N. Uversky

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Structural and Functional Analysis of “non-smelly” Proteins, Jing Yan, Jianlin Cheng, Lukasz Kurgan, and Vladimir N. Uversky

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An in-vitro Elucidation of Inhibitory Potential of Carminic Acid: Possible Therapeutic Approach for Neurodegenerative Diseases, Syed Mohammad Zakariya, Mohammad Furkan, Masihuz Zaman, Tajalli Ilm Chandel, Syed Moasfar Ali, Vladimir N. Uversky, and Rizwan Hasan Khan

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Classification of Chromosomal DNA Sequences Using Hybrid Deep Learning Architectures, Du Zhihua, Xiangdong Xiao, and Vladimir N. Uversky

Submissions from 2019

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Binding of LcrV Protein from Yersinia pestis to Human T-cells Induces Apoptosis, Which is Completely Blocked by Specific Antibodies, Vyacheslav M. Abramov, Igor V. Kosarev, Vladimir L. Motin, Valentin S. Khlebnikov, Raisa N. Vasilenko, Vadim K. Sakulin, Andrey V. Machulin, Vladimir N. Uversky, and Andrey V. Karlyshev

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Modulating Insulin Fibrillation Using Engineered B-Chains with Mutated C-Termini, Mohsen Akbarian, Reza Yousefi, Ali Akbar Moosavi-Movahedi, Atta Ahmad, and Vladimir N. Uversky

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An Interplay of Structure and Intrinsic Disorder in the Functionality of Peptidylarginine Deiminases, a Family of Key Autoimmunity-related Enzymes, Mohammed Alghamdi; Ghamdi, Khaled Al Ghamdi; Rizwan H. Khan; Vladimir N. Uversky; and Elrashdy M. Redwan

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Synergistic Killing of Pathogenic Escherichia Coli Using Camel Lactoferrin from Different Saudi Camel Clans and Various Antibiotics, Hussein A. Almehdar, Nawal Abd El-Baky, Abdulqader A. Alhaider, Saud A. Almuhaideb, Abdullah A. Alhaider, Raed S. Albiheyri, Vladimir N. Uversky, and Elrashdy M. Redwan

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The Structural and Functional Diversity of Intrinsically Disordered Regions in Transmembrane Proteins, Rajeswari Appadurai, Vladimir N. Uversky, and Anand Srivastava

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Molecular Basis of the Inhibition and Disaggregation of Thermally-induced Amyloid Fibrils of Human Serum Albumin by an Anti-Parkinson's Drug, Benserazide Hydrochloride, Tajalli Ilm Chandel, Aiman Masroor, Mohammad Khursheed Siddiqi, Ibrar Ahmad Siddique, Ishrat Jahan, Maroof Ali, Shahid M. Nayeem, Vladimir N. Uversky, and Rizwan Hasan Khan

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A Multiparametric Analysis of the Synergistic Impact of Anti-Parkinson's Drugs on the Fibrillation of Human Serum Albumin, Tajalli Ilm Chandel, Nida Zaidi, Masihuz Zaman, Ishrat Jahan, Aiman Masroor, Ibrar Ahmad Siddique, Shahid M. Nayeem, Maroof Ali, Vladimir N. Uversky, and Rizwan Hasan Khan

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Network Mapping of the Conformational Heterogeneity of SOD1 by Deploying Statistical Cluster Analysis of FTIR Spectra, Sourav Chowdhury, Sagnik Sen, Amrita Banerjee, Vladimir N. Uversky, Ujjwal Maulik, and Krishnananda Chattopadhyay

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Phenotypic Screens Reveal Posaconazole as a Rapidly Acting Amebicidal Combination Partner for Treatment of Primary Amoebic Meningoencephalitis, Beatrice L. Colon, Christopher A. Rice, R. Kiplin Guy, and Dennis E. Kyle

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Cyclized NDGA Modifies Dynamic Α-synuclein Monomers Preventing Aggregation and Toxicity, Malcolm J. Daniels, J. Brucker Nourse, Hanna Kim, Valerio Sainati, Marco Schiavina, Maria Grazia Murrali, Buyan Pan, John J. Ferrie, Conor M. Haney, Rani Moons, Neal S. Gould, Antonino Natalello, Rita Grandori, Frank Sobott, E. James Petersson, Elizabeth Rhoades, Roberta Pierattelli, Isabella Felli, Vladimir N. Uversky, Kim A. Caldwell, Guy A. Caldwell, Edward S. Krol, and Harry Ischiropoulos

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Repeated Repeat Problems: Combinatorial Effect of C9orf72-derived Dipeptide Repeat Proteins, April L. Darling, Leonid Breydo, Emma G. Rivas, Niad T. Gebru, Dali Zheng, Jeremy D. Baker, Laura J. Blair, Chad A. Dickey, John Koren, and Vladimir N. Uversky

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Effects of Sodium Chloride and Sodium Perchlorate on Properties and Partition Behavior of Solutes in Aqueous Dextran-polyethylene Glycol and Polyethylene Glycol-sodium Sulfate Two-phase Systems, Nuno R. da Silva, Luisa A. Ferreira, José A. Teixeira, Vladimir N. Uversky, and Boris Y. Zaslavsky

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An Empirical Study of Amide–heteroarene π-stacking Interactions using Reversible Inhibitors of a Bacterial Serine Hydrolase, Kyle DeFrees, M. Trent Kemp, Xochina ElHilali-Pollard, XiuJun Zhang, Ahmed Mohamed, Yu Chen, and Adam R. Renslo

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Does Intrinsic Disorder in Proteins Favor Their Interaction with Lipids?, Evgenia Deryusheva, Ekaterina Nemashkalova, Marie Galloux, Charels-Adrien Richard, Jean-François Eléouët, Denis Kovacs, Karo Van Belle, Peter Tompa, Vladimir Uversky, and Sergei Permyakov

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Ferroptosis – An Iron- and Disorder-dependent Programmed Cell Death, Mak B. Djulbegovic and Vladimir N. Uversky

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Effects of Amino Acids on Solvent Properties of Water, Luisa A. Ferreira, Vladimir N. Uversky, and Boris Y. Zaslavsky

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Multi-functionality of Proteins Involved in GPCR and G Protein Signaling: Making Sense of Structure–function Continuum with Intrinsic Disorder-based Proteoforms, Alexander V. Fonin, April L. Darling, Irina M. Kuznetsova, Konstantin K. Turoverov, and Vladimir N. Uversky

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Folding of Poly-amino Acids and Intrinsically Disordered Proteins in Overcrowded Milieu Induced by PH Change, Alexander V. Fonin, Olga V. Stepanenko, Asiia K. Sitdikova, Iuliia A. Antifeeva, Elena I. Kostyleva, Alexander M. Polyanichko, Maksim M. Karasev, Sergey A. Silonov, Olga I. Povarova, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin К. Turoverov

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Nanoparticle Formulations in the Diagnosis and Therapy of Alzheimer's Disease, Jyoti Gupta, Munazza Tamkeen Fatima, Zeyaul Islam, Rizwan Hasan Khan, Vladimir N. Uversky, and Parveen Salahuddin

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Molecular Dynamics Analysis of the Effects of GTP, GDP and Benzimidazole Derivative on Structural Dynamics of a Cell Division Protein FtsZ from Mycobacterium Tuberculosis, Supriya Hakeem, Inderpal Singh, Preeti Sharma, Anshul Uppal, Yugal Khajuria, Vijeshwar Verma, Vladimir N. Uversky, and Ratna Chandra

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Molecular Docking of Aβ1–40 Peptide and Its Iowa D23N Mutant Using Small Molecule Inhibitors: Possible Mechanisms of Aβ-peptide Inhibition, Rizwan Hasan Khan, Mohammad Khursheed Siddiqi, Vladimir N. Uversky, and Parveen Salahuddin

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Effect of C-terminal His-tag and Purification Routine on the Activity and Structure of the Metalloenzyme, L-alanyl-d-glutamate Peptidase of the Bacteriophage T5, Victor P. Kutyshenko, Galina V. Mikoulinskaia, Sergei V. Chernyshov, Alexander Y. Yegorov, Dmitry A. Prokhorov, and Vladimir N. Uversky

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Effect of Cu2+ and Zn2+ Ions on Human Serum Albumin Interaction with Plasma Unsaturated Fatty Acids, Ekaterina L. Nemashkalova, Eugene A. Permyakov, Vladimir N. Uversky, Sergei E. Permyakov, and Ekaterina A. Litus

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Perturbation of Water Structure by Water-polymer Interactions Probed by FTIR and Polarized Raman Spectroscopy, Jessica Pavelec, David DiGuiseppi, Boris Y. Zavlavsky, Vladimir N. Uversky, and Reinhard Schweitzer-Stenner