Submissions from 2015
Intrinsic Disorder in Biomarkers of Insulin Resistance, Hypoadiponectinemia, and Endothelial Dysfunction among the Type 2 Diabetic Patients, Osama H. Jiffri, Fadwa M. Al-Sharif, Essam H. Jiffri, and Vladimir N. Uversky
Intrinsic Disorder in Biomarkers of Insulin Resistance, Hypoadiponectinemia, and Endothelial Dysfunction Among the Type 2 Diabetic Patients, Osama H. Jiffri, Fadwa M. Al-Sharif, Essam H. Jiffri, and Vladimir N. Uversky
“In-plant” NMR: Analysis of the Intact Plant Vesicularia Dubyana by High Resolution NMR Spectroscopy, Viktor P. Kutyshenko, Peter Beskaravayny, and Vladimir N. Uversky
Beyond the Excluded Volume Effects: Mechanistic Complexity of the Crowded Milieu, Irina M. Kuznetsova, Boris Y. Zaslavsky, Leonid Breydo, Konstantin K. Turoverov, and Vladimir N. Uversky
Antibacterial Properties and Atomic Resolution X-ray Complex Crystal Structure of a Ruthenocene Conjugated β-lactam Antibiotic, Eric M. Lewandowski, Joanna Skiba, Nicholas J. Torelli, Aleksandra Rajnisz, Jolanta Solecka, Konrad Kowalski, and Yu Chen
Pliable Natural Biocide: Jaburetox is an Intrinsically Disordered Insecticidal and Fungicidal Polypeptide Derived from Jack Bean Urease, Fernanda C. Lopes, Olena Dobrovolska, Rafael Real-Guerra, Valquiria Broll, Barbara Zambelli, Francesco Musiani, Vladimir N. Uversky, Célia R. Carlini, and Stefano Ciurli
Identification of Intrinsically Disordered Regions in PTEN and Delineation of Its Function via a Network Approach, Prerna Malaney, Vladimir N. Uversky, and Vrushank Davé
Unstructural Biology of the Dengue Virus Proteins, Fanchi Meng, Reaid A. Badierah, Hussein A. Almehdar, Elrashdy M. Redwan, Lukasz Kurgan, and Vladimir N Uversky
Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography, Derek A. Nichols, Jacqueline C. Hargis, Ruslan Sanishvili, Priyadarshini Jaishankar, Kyle Defrees, Emmanuel W. Smith, Kenneth K. Wang, Fabio Prati, Adam R. Renslo, H. Lee Woodcock, and Yu Chen
Exceptionally Abundant Exceptions: Comprehensive Characterization of Intrinsic Disorder in All Domains of Life, Zhenling Peng, Jing Yan, Xiao Fan, Marcin J. Mizianty, Bin Xue, Kui Wang, Gang Hu, Vladimir N. Uversky, and Lukasz Kurgan
Does Intrinsically Disordered Caldesmon Bind Calmodulin via the “buttons on a string” Mechanism?, Sergei E. Permyakov, Eugene A. Permyakov, and Vladimir N. Uversky
Does Intrinsically Disordered Caldesmon Bind Calmodulin via the “Buttons on a String” Mechanism?, Sergei E. Permyakov, Eugene A. Permyakov, and Vladimir N. Uversky
Intrinsically Disordered Caldesmon Binds Calmodulin via the “buttons on a string” Mechanism, Sergei E. Permyakov, Eugene A. Permyakov, and Vladimir N. Uversky
Identifying Similar Patterns of Structural Flexibility in Proteins by Disorder Prediction and Dynamic Programming, Aidan Petrovich, Adam Borne, Vladimir N. Uversky, and Bin Xue
Identification of Proteins Associated with Amyloidosis by Polarity Index Method., Carlos Polanco, José Lino Samaniego, Vladimir N N. Uversky, Jorge Alberto Castañón-González, Thomas Buhse, Marili Leopold-Sordo, Alejandro Madero-Arteaga, Alicia Morales-Reyes, Lourdes Tavera-Sierra, Jesus A. González-Bernal, and Miguel Arias-Estrada
Role of Monomer Arrangement in the Amyloid Self-assembly, Alexander Portillo, Mohtadin Hashemi, Yuliang Zhang, Leonid Breydo, Vladimir N. Uversky, and Yuri L. Lyubchenko
Globular Actin is a Partially Intrinsically Disordered Protein with a Quasi-Stationary Structure, Olga I. Povarova, Iuliia A. Gagarskaia, Vladimir N. Uversky, Irina M. Kuznetsova, and Konstantin K. Turoverov
High-resolution NMR Structure of a Zn2+-containing Form of the Bacteriophage T5 L-alanyl-D-glutamate Peptidase, Dmitry A. Prokhorov, Galina V. Mikoulinskaia, Nikolai V. Molochkov, Vladimir N. Uversky, and Victor P. Kutyshenko
Potential Antiviral Activities of Camel, Bovine, and Human Lactoperoxidases Against Hepatitis C Virus Genotype 4, Elrashdy M. Redwan, Hussein A. Almehdar, Esmail M. El-Fakharany, Abdul-Wahab K. Baig, and Vladimir N. Uversky
Disorder in Milk Proteins: Caseins, Intrinsically Disordered Colloids, Elrashdy M. Redwan, Bin Xue, Hussein A. Almehdar, and Vladimir N. Uversky
Hidden Disorder Propensity of the N-terminal Segment of Universal Adapter Protein 14-3-3 is Manifested in Its Monomeric Form: Novel Insights into Protein Dimerization and Multifunctionality, Nikolai N. Sluchanko and Vladimir N. Uversky
Structures of Pseudomonas aeruginosa LpxA Reveal the Basis for Its Substrate Selectivity, Emmanuel W. Smith, XiuJun Zhang, Cyrus Behzadi, Logan D. Andrews, Frederick Cohen, and Yu Chen
Structure and Stability of Recombinant Bovine Odorant-Binding Protein: I. Design and Analysis of Monomeric Mutants, Olga V. Stepanenko, Denis O. Roginskii, Olesya V. Stepanenko, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov
Structure and Stability of Recombinant Bovine Odorant-binding Protein: I. Design and Analysis of Monomeric Mutants, Olga V. Stepanenko, Denis O. Roginskii, Olesya V. Stepanenko, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov
Structure and Stability of Recombinant Bovine Odorant-binding Protein: II. Unfolding of the Monomeric Forms, Olga V. Stepanenko, Denis O. Roginskii, Olesya V. Stepanenko, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov
Biophysical Methods to Investigate Intrinsically Disordered Proteins: Avoiding an “Elephant and Blind Men” Situation, Vladimir N. Uversky
Biophysical Methods to Investigate Intrinsically Disordered Proteins: Avoiding an “Elephant and Blind Men” Situation, Vladimir N. Uversky
Commentary: Hot, Hotter, and Hottest Trends in α-synuclein Research, Vladimir N. Uversky
Functional Roles of Transiently and Intrinsically Disordered Regions Within Proteins, Vladimir N. Uversky
Intrinsically Disordered Proteins and Their (disordered) Proteomes in Neurodegenerative Disorders, Vladimir N. Uversky
Paradoxes and Wonders of Intrinsic Disorder: Prevalence of Exceptionality, Vladimir N. Uversky
Pliability of Protein Complexes and Complexity of Protein Pliability, Vladimir N. Uversky
Protein Misfolding in Lipid-Mimetic Environments, Vladimir N. Uversky
Protein Misfolding in Lipid-mimetic Environments, Vladimir N. Uversky
Proteins without Unique 3D Structures: Biotechnological Applications of Intrinsically Unstable/disordered Proteins, Vladimir N. Uversky
The Intrinsic Disorder Alphabet. III. Dual Personality of Serine, Vladimir N. Uversky
The Multifaceted Roles of Intrinsic Disorder in Protein Complexes, Vladimir N. Uversky
Unreported Intrinsic Disorder in Proteins: Disorder Emergency Room, Vladimir N. Uversky
Intrinsically Disordered Proteins as Crucial Constituents of Cellular Aqueous Two Phase Systems and Coacervates, Vladimir N. Uversky, Irina M. Kuznetsova, Konstantin K. Turoverov, and Boris Zaslavsky
Fendiline Inhibits Proliferation and Invasion of Pancreatic Cancer Cells by Interfering with ADAM10 Activation and β-catenin Signaling, Neha Woods, Jose Trevino, Domenico Coppola, Srikumar Chellappan, Shengyu Yang, and Jaya Padmanabhan
In Various Protein Complexes, Disordered Protomers Have Large Per-residue Surface Areas and Area of Protein-, DNA- and RNA-binding Interfaces, Zhonghua Wu, Gang Hu, Jianyi Yang, Zhenling Peng, Vladimir N. Uversky, and Lukasz Kurgan
Biocidal Activity of Chicken Defensin-9 against Microbial Pathogens, Haitham Yacoub, Salem El-Hamidy, Maged Mahmoud, Mohamed Baeshen, Hussein Almehdar, Vladimir N. Uversky, Elrashdy Redwan, Omar Al-Maghrabi, and Ahmed Elazzazy
Molecular recognition features (MoRFs) in three domains of life, Jing Yan, A. Keith Dunker, Vladimir N. Uversky, and Lukasz Kurgan
Submissions from 2014
Probiotic Properties of Lactobacillus crispatus 2,029: Homeostatic Interaction with Cervicovaginal Epithelial Cells and Antagonistic Activity to Genitourinary Pathogens, Vyacheslav Abramov, Valentin Khlebnikov, Igor Kosarev, Guldana Bairamova, Raisa Vasilenko, Natalia Suzina, Andrey Machulin, Vadim Sakulin, Natalia Kulikova, Nadezhda Vasilenko, Andrey Karlyshev, Vladimir Uversky, Michael L. Chikindas, and Vyacheslav Melnikov
Structural Heterogeneity and Multifunctionality of Lactoferrin, Abdulgader H. Albar, Hussein A. Almehdar, Vladimir N. Uversky, and Elrashdy M. Redwan
Toward a Common Aggregation Mechanism for a β-Barrel Protein Family: Insights Derived from a Stable Dimeric Species, Carla R. Angelani, Lucrecia M. Curto, Inés S. Cabanas, Julio J. Caramelo, Vladimir N. Uversky, and José M. Delfino
The Crowd You're In With: Effects of Different Types of Crowding Agents on Protein Aggregation, Leonid Breydo, Krishna D. Reddy, Alessandro Piai, Isabella C. Felli, Roberta Pierattelli, and Vladimir N. Uversky
Molecular Mechanisms of Protein Misfolding, Leonid Breydo and Vladimir N. Uversky
Identifying Novel Cell Cycle Proteins in Apicomplexa Parasites Through Co-expression Decision Analysis, Carrie L. Butler, Olivier Lucas, Stefan Wuchty, Bin Xue, Vladimir N. Uversky, and Michael White
The Intrinsic Disorder Status of the Human Hepatitis C Virus Proteome, Xiao Fan, Bin Xue, Patrick T. Dolan, Douglas J. LaCount, Lukasz Kurgan, and Vladimir N. Uversky
Structural Features Important for Differences in Protein Partitioning in Aqueous Dextran-Polyethylene Glycol Two-Phase Systems of Different Ionic Compositions, Luisa Ferreira, Xiao Fan, Larissa M. Mikheeva, Pedro P. Madeira, Lukasz Kurgan, Vladimir N Uversky, and Boris Y. Zaslavsky
Disordered Proteinaceous Machines, Monika Fuxreiter, Ágnes Tóth-Petróczy, Daniel A. Kraut, Andreas T. Matouschek, Roderick Y. H. Lim, Bin Xue, Lukasz Kurgan, and Vladimir N. Uversky
Introducing Protein Intrinsic Disorder, Johnny Habchi, Peter Tompa, Sonia Longhi, and Vladimir N. Uversky
Introducing Protein Intrinsic Disorder, Johnny Habchi, Peter Tompa, Sonia Longhi, and Vladimir N. Uversky
Improving Protein Order-Disorder Classification Using Charge-Hydropathy Plots, Feihe Huang, Christopher J. Oldfield, Bin Xue, Wei-Lun Hsu, Jingwei Meng, Xiaowen Liu, Li Shen, Pedro Romero, Vladimir N Uversky, and Keith A. Dunker
Conditionally and Transiently Disordered Proteins: Awakening Cryptic Disorder To Regulate Protein Function, Ursula Jakob, Richard Kriwacki, and Vladimir N. Uversky
Conditionally and Transiently Disordered Proteins: Awakening Cryptic Disorder To Regulate Protein Function, Ursula Jakob, Richard Kriwacki, and Vladimir N. Uversky
Presence and Utility of Intrinsically Disordered Regions in Kinases, Jaymin J. Kathiriya, Ravi Ramesh Pathak, Eric Clayman, Bin Xue, Vladimir N. Uversky, and Vrushank Davé
Intracellular Processing of Disease-Associated α-Synuclein in the Human Brain Suggests Prion-Like Cell-to-Cell Spread, Gabor G. Kovacs, Leonid Breydo, Ryan Green, Victor Kis, Gina Puska, Péter Lőrincz, Laura Perju-Dumbrava, Regina Giera, Walter Pirker, Mirjam Lutz, Ingolf Lachmann, Herbet Budka, Vladimir N. Uversky, Kinga Molnar, and Lajos László
Dancing Retro: Solution Structure and Micelle Interactions of The Retro-sh3-domain, Retro-shh-‘bergerac’, Victor P. Kutyshenko, Dmitry Prokhorov, Nikolai V. Molochkov, Mars G. Sharapov, Igor Kolesnikov, and Vladimir N. Uversky
What Macromolecular Crowding Can Do to a Protein, Irina M. Kuznetsova, Konstantin K. Turoverov, and Vladimir N. Uversky
Contribution of Proline to the Pre-structuring Tendency of Transient Helical Secondary Structure Elements in Intrinsically Disordered Proteins, Chewook Lee, Lajos Kalmar, Bin Xue, Peter Tompa, Gary Daughdrill, Vladimir N. Uversky, and Kyou-Hoon Han
Amino Acid/Water Interactions Study: A New Amino Acid Scale, Pedro P. Madeira, Ana Bessa, Luís Álvares-Ribeiro, M. Raquel Aires-Barros, Alírio E. Rodrigues, Vladimir N. Uversky, and Boris Y. Zaslavsky
Prediction of Intrinsic Disorder in Proteins Using MFDp2, Marcin J. Mizianty, Marcin J. Mizianty, Vladimir Uversky, and Lukasz Kurgan
A Putative Role of the Sup35p C-terminal Domain in the Cytoskeleton Organization during Yeast Mitosis, Insung Na, Krishna D. Reddy, Leonid Breydo, Bin Xue, and Vladimir N. Uversky
A Putative Role of the Sup35p C-Terminal Domain in the Cytoskeleton Organization During Yeast Mitosis, Insung Na, Krishna D. Reddy, Leonid Breydo, Bin Xue, and Vladimir N. Uversky
Ligands for Glaucoma-Associated Myocilin Discovered by a Generic Binding Assay, Susan D. Orwig, Pamela V. Chi, Yuhong Du, Shannon E. Hill, Marchello A. Cavitt, Amrithaa Suntharalingam, Katherine C. Turnage, Chad A. Dickey, Stefan France, Haian Fu, and Raquel L. Lieberman
The Structural and Functional Signatures of Proteins that Undergo Multiple Events of Post-Translational Modification, Vikas Pejaver, Wei-Lun Hsu, Fuxiao Xin, A. Keith Dunker, Vladimir N. Uversky, and Predrag Radivojac
The Structural and Functional Signatures of Proteins that Undergo Multiple Events of Post-translational Modification, Vikas Pejaver, Wei-Lun Hsu, Fuxiao Xin, A. Keith Dunker, Vladimir N. Uversky, and Predrag Radivojac
A Creature with a Hundred Waggly Tails: Intrinsically Disordered Proteins in the Ribosome, Zhenling Peng, Christopher J. Oldfield, Bin Xue, Marcin J. Mizianty, A. Keith Dunker, Lukasz Kurgan, and Vladimir N. Uversky
Intrinsic Disorder in the BK Channel and Its Interactome, Zhenling Peng, Yoshihisa Sakai, Lukasz Kurgan, Bernd Sokolowski, and Vladimir N. Uversky
Identification of Atg3 as an Intrinsically Disordered Polypeptide Yields Insights into the Molecular Dynamics of Autophagy-Related Proteins in Yeast, Hana Popelka, Vladimir N Uversky, and Daniel J. Klionsky
Actinous Enigma Or Enigmatic Actin: Folding, Structure, and Functions of the Most Abundant Eukaryotic Protein, Olga I. Povarova, Vladimir N. Uversky, Irina M. Kuznetsova, and Konstantin K. Turoverov
DRM1 and DRM2 Expression Regulation: Potential Role of Splice Variants in Response to Stress and Environmental Factors in Arabidopsis, Georgina M. Rae, Vladimir N Uversky, Karine David, and Marion Wood
Digested Disorder: Quarterly Intrinsic Disorder Digest (July–August–September, 2013), Krishna D. Reddy, Shelly Deforte, and Vladimir N. Uversky
Screening the Anti Infectivity Potentials of Native N- and C-lobes Derived from the Camel Lactoferrin Against Hepatitis C Virus, Elrashdy M. Redwan, Esmail M. El-Fakharany, Vladimir N. Uversky, and Moustafa H. Linjawi
Potential Lactoferrin Activity Against Pathogenic Viruses, Elrashdy M. Redwan, Vladimir N. Uversky, Esmail M. El-Fakharany, and Hussein Al-Mehdar
Catalytically Active Alkaline Molten Globular Enzyme: Effect of pH and Temperature on the Structural Integrity of 5-Aminolevulinate Synthase, Bosko M. Stojanovski, Leonid Breydo, Gregory A. Hunter, Vladimir N. Uversky, and Gloria C. Ferreira
The Intrinsically Disordered Structural Platform of the Plant Defence Hub Protein RPM1-Interacting Protein 4 Provides Insights into Its Mode of Action in the Host-Pathogen Interface and Evolution of the Nitrate-Induced Domain Protein Family, Xiaolin Sun, David R. Greenwood, Matthew D. Templeton, David S. Libich, Tony K. McGhie, Bin Xue, Minsoo Yoon, Wei Cui, Christopher A. Kirk, William T. Jones, Vladimir N. Uversky, and Erik H. A. Rikkerink
Amino Acid Code for Potein Folding, Misfolding, and Non-folding, Alexey V. Uversky and Vladimir N. Uversky
Unreported Intrinsic Disorder in Proteins: Building Connections to the Literature on IDPs, Vladimir N. Uversky
Fundamentals of Protein Folding, Vladimir N. Uversky
Introduction to Intrinsically Disordered Proteins (IDPs), Vladimir N. Uversky
The Triple Power of D³: Protein Intrinsic Disorder in Degenerative Diseases, Vladimir N. Uversky
Wrecked Regulation of Intrinsically Disordered Proteins in Diseases: Pathogenicity of Deregulated Regulators, Vladimir N. Uversky
Pathological Unfoldomics of Uncontrolled Chaos: Intrinsically Disordered Proteins and Human Diseases, Vladimir N. Uversky, Vrushank Davé, Lilia M. Iakoucheva, Prerna Malaney, Steven J. Metallo, Ravi Ramesh Pathak, and Andreas C. Joerger
Classification of Intrinsically Disordered Regions and Proteins, Robin van der Lee, Marija Buljan, Benjamin Lang, Robert J. Weatheritt, Gary W. Daughdrill, A Keith Dunker, Monika Fuxreiter, Julian Gough, Joerg Gsponer, David T. Jones, Philip M. Kim, Richard W. Kriwacki, Christopher J. Oldfield, Rohit V. Pappu, Peter Tompa, Vladimir N. Uversky, Peter E. Wright, and M. Madan Babu
pE-DB: A Database of Structural Ensembles of Intrinsically Disordered and Unfolded Proteins, Mihaly Varadi, Simone Kosol, Pierre Lebrun, Erica Valentini, Martin Blackledge, A. Keith Dunker, Isabella C. Felli, Julie D. Forman-Kay, Richard Kriwacki, Roberta Pierattelli, Joel Sussman, Dmitri I. Svergun, Vladimir N. Uversky, Michele Vendruscolo, David Wishart, Peter E. Wright, and Peter Tompa
Genetic Manipulation of the Toxoplasma gondii Genome by Fosmid Recombineering, Sumiti Vinayak, Carrie F. Brooks, Anatoli Naumov, Elena Suvorova, Michael W. White, and Boris Striepen
Structural Disorder in Viral Proteins, Bin Xue, David Blocquel, Johnny Habchi, Alexey V. Uversky, Lukasz Kurgan, Vladimir N. Uversky, and Sonia Longhi
Disordered Interactome of Human Papillomavirus, Bin Xue, Ketaki Ganti, Alejandro Rabionet, Lawrence Banks, and Vladimir N. Uversky
Intrinsic Disorder in Proteins Involved in the Innate Antiviral Immunity: Another Flexible Side of a Molecular Arms Race, Bin Xue and Vladimir N Uversky
Submissions from 2013
The Effects of Mutations on Protein Function: A Comparative Study of Three Databases of Mutations in Humans, Ariel Azia, Vladimir N. Uversky, Amnon Horovitz, and Ron Unger
Nonstructural Protein 2 (nsP2) of Chikungunya Virus (CHIKV) Enhances Protective Immunity Mediated by a CHIKV Envelope Protein Expressing DNA Vaccine, Huihui Bao, Aarti A. Ramanathan, Omkar Kawalakar, Senthil G. Sundaram, Colleen Tingey, Charoran B. Bian, Nagarajan Muruganandam, Paluru Vijayachari, Niranjan Y. Sardesai, David B. Weiner, Kenneth E. Ugen, and Karuppiah Muthumani
Interplay Between Estrogen Receptor and AKT in Estradiol-induced Alternative Splicing, Poornima Bhat-Nakshatri, Eun-Kyung Song, Nikail R. Collins, Vladimir N. Uversky, A. Keith Dunker, Bert W. O'Malley, Tim R. Geistlinger, Jason S. Carroll, Myles Brown, and Harikrishna Nakshatri
Accelerated Neurodegeneration Through Chaperone-mediated Oligomerization of Tau, Laura J. Blair, Bryce A. Nordhues, Shannon E. Hill, K. Matthew Scaglione, John C. O'Leary III, Sarah N. Fontaine, Leonid Breydo, Bo Zhang, Pengfei Li, Li Wang, Carl Cotman, Henry L. Paulson, Martin Muschol, Vladimir N. Uversky, Torsten Klengel, Elisabeth Binder, Rakez Kayed, Todd E. Golde, Nicole Berchtold, and Chad A. Dickey
P1–058: The Hsp90 Co-chaperone FKBP51 Produces Neurotoxic Tau Oligomers: Implication for Aging and Alzheimer's Disease, Laura Blair, Bryce Nordhues, Shannon Hill, K. Matthew Scaglione, John O'Leary, Leonid Breydo, Zhang Bo, Pengfei Li, Lily Wang, Carl Cotman, Henry Paulson, Martin Muschol, Vladimir N. Uversky, Torsten Klengel, Elisabeth Binder, Rakez Kayed, Nicole Berchtold, Todd Golde, and Chad Dickey
Solvent Interaction Analysis of Intrinsically Disordered Proteins in Aqueous Two-phase Systems, Leonid Breydo, Larissa M. Mikheeva, Pedro P. Madeira, Boris Y. Zaslavsky, and Vladimir N. Uversky
Dysregulated Alternative Splicing Pattern of PKC during Differentiation of Human Preadipocytes Represents Distinct Differences between Lean and Obese Adipocytes, Gay Carter, André Apostolatos, Rekha Patel, Abhishek Mathur, Denise Cooper, Michel Murr, and Niketa A. Patel
Modulating the Intrinsic Disorder in the Cytoplasmic Domain Alters the Biological Activity of the N-Methyl-D-spartate-sensitive Glutamate Receptor, Ucheor B. Choi, Rashek Kazi, Natalie Stenzoski, Lonnie P. Wollmuth, Vladimir N. Uversky, and Mark E. Bowen
