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Submissions from 2019

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An Interplay of Structure and Intrinsic Disorder in the Functionality of Peptidylarginine Deiminases, a Family of Key Autoimmunity-related Enzymes, Mohammed Alghamdi; Ghamdi, Khaled Al Ghamdi; Rizwan H. Khan; Vladimir N. Uversky; and Elrashdy M. Redwan

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Synergistic Killing of Pathogenic Escherichia Coli Using Camel Lactoferrin from Different Saudi Camel Clans and Various Antibiotics, Hussein A. Almehdar, Nawal Abd El-Baky, Abdulqader A. Alhaider, Saud A. Almuhaideb, Abdullah A. Alhaider, Raed S. Albiheyri, Vladimir N. Uversky, and Elrashdy M. Redwan

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Many-to-one Binding by Intrinsically Disordered Protein Regions, Wei-Lun Alterovitz, Eshel Faraggi, Christopher J. Oldfield, Jingwei Meng, Bin Xue, Fei Huang, Pedro Romero, Andrzej Kloczkowski, Vladimir N. Uversky, and A. Keith Dunker

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The Structural and Functional Diversity of Intrinsically Disordered Regions in Transmembrane Proteins, Rajeswari Appadurai, Vladimir N. Uversky, and Anand Srivastava

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Molecular Basis of the Inhibition and Disaggregation of Thermally-induced Amyloid Fibrils of Human Serum Albumin by an Anti-Parkinson's Drug, Benserazide Hydrochloride, Tajalli Ilm Chandel, Aiman Masroor, Mohammad Khursheed Siddiqi, Ibrar Ahmad Siddique, Ishrat Jahan, Maroof Ali, Shahid M. Nayeem, Vladimir N. Uversky, and Rizwan Hasan Khan

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A Multiparametric Analysis of the Synergistic Impact of Anti-Parkinson's Drugs on the Fibrillation of Human Serum Albumin, Tajalli Ilm Chandel, Nida Zaidi, Masihuz Zaman, Ishrat Jahan, Aiman Masroor, Ibrar Ahmad Siddique, Shahid M. Nayeem, Maroof Ali, Vladimir N. Uversky, and Rizwan Hasan Khan

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Network Mapping of the Conformational Heterogeneity of SOD1 by Deploying Statistical Cluster Analysis of FTIR Spectra, Sourav Chowdhury, Sagnik Sen, Amrita Banerjee, Vladimir N. Uversky, Ujjwal Maulik, and Krishnananda Chattopadhyay

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Evolutionary Analyses of Sequence and Structure Space Unravel the Structural Facets of SOD1, Sourav Chowdury, Dwipanjan Sanyal, Sagnik Sen, Vladimir N. Uversky, Ujjwal Maulik, and Krishnananda Chattopadhyay

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Phenotypic Screens Reveal Posaconazole as a Rapidly Acting Amebicidal Combination Partner for Treatment of Primary Amoebic Meningoencephalitis, Beatrice L. Colon, Christopher A. Rice, R. Kiplin Guy, and Dennis E. Kyle

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Intrinsically Disordered Proteins in Various Hypotheses on the Pathogenesis of Alzheimer's and Parkinson's Diseases, Orkid Coskuner and Vladimir N. Uversky

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Alanine Scanning Effects on the Biochemical and Biophysical Properties of Intrinsically Disordered Proteins: A Case Study of the Histidine to Alanine Mutations in Amyloid-β42, Orkid Coskuner-Weber and Vladimir N. Uversky

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Cyclized NDGA Modifies Dynamic Α-synuclein Monomers Preventing Aggregation and Toxicity, Malcolm J. Daniels, J. Brucker Nourse, Hanna Kim, Valerio Sainati, Marco Schiavina, Maria Grazia Murrali, Buyan Pan, John J. Ferrie, Conor M. Haney, Rani Moons, Neal S. Gould, Antonino Natalello, Rita Grandori, Frank Sobott, E. James Petersson, Elizabeth Rhoades, Roberta Pierattelli, Isabella Felli, Vladimir N. Uversky, Kim A. Caldwell, Guy A. Caldwell, Edward S. Krol, and Harry Ischiropoulos

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Repeated Repeat Problems: Combinatorial Effect of C9orf72-derived Dipeptide Repeat Proteins, April L. Darling, Leonid Breydo, Emma G. Rivas, Niad T. Gebru, Dali Zheng, Jeremy D. Baker, Laura J. Blair, Chad A. Dickey, John Koren, and Vladimir N. Uversky

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Intrinsic Disorder-based Emergence in Cellular Biology: Physiological and Pathological Liquid-liquid Phase Transitions in Cells, April L. Darling, Boris Zaslavsky, and Vladimir N. Uversky

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Effects of Sodium Chloride and Sodium Perchlorate on Properties and Partition Behavior of Solutes in Aqueous Dextran-polyethylene Glycol and Polyethylene Glycol-sodium Sulfate Two-phase Systems, Nuno R. da Silva, Luisa A. Ferreira, José A. Teixeira, Vladimir N. Uversky, and Boris Y. Zaslavsky

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An Empirical Study of Amide–heteroarene π-stacking Interactions using Reversible Inhibitors of a Bacterial Serine Hydrolase, Kyle DeFrees, M. Trent Kemp, Xochina ElHilali-Pollard, XiuJun Zhang, Ahmed Mohamed, Yu Chen, and Adam R. Renslo

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Does Intrinsic Disorder in Proteins Favor Their Interaction with Lipids?, Evgenia Deryusheva, Ekaterina Nemashkalova, Marie Galloux, Charels-Adrien Richard, Jean-François Eléouët, Denis Kovacs, Karo Van Belle, Peter Tompa, Vladimir Uversky, and Sergei Permyakov

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Ferroptosis – An Iron- and Disorder-dependent Programmed Cell Death, Mak B. Djulbegovic and Vladimir N. Uversky

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Effects of Amino Acids on Solvent Properties of Water, Luisa A. Ferreira, Vladimir N. Uversky, and Boris Y. Zaslavsky

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Multi-functionality of Proteins Involved in GPCR and G Protein Signaling: Making Sense of Structure–function Continuum with Intrinsic Disorder-based Proteoforms, Alexander V. Fonin, April L. Darling, Irina M. Kuznetsova, Konstantin K. Turoverov, and Vladimir N. Uversky

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Folding of Poly-amino Acids and Intrinsically Disordered Proteins in Overcrowded Milieu Induced by PH Change, Alexander V. Fonin, Olga V. Stepanenko, Asiia K. Sitdikova, Iuliia A. Antifeeva, Elena I. Kostyleva, Alexander M. Polyanichko, Maksim M. Karasev, Sergey A. Silonov, Olga I. Povarova, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin К. Turoverov

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HIV Vaccine Mystery and Viral Shell Disorder, Gerard Kian-Meng Goh, A. Keith Dunker, James A. Foster, and Vladimir N. Uversky

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Zika and Flavivirus Shell Disorder: Virulence and Fetal Morbidity, Gerard Kian-Meng Goh, A. Keith Dunker, James A. Foster, and Vladimir N. Uversky

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Nanoparticle Formulations in the Diagnosis and Therapy of Alzheimer's Disease, Jyoti Gupta, Munazza Tamkeen Fatima, Zeyaul Islam, Rizwan Hasan Khan, Vladimir N. Uversky, and Parveen Salahuddin

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Intrinsic Disorder of the BAF Complex: Roles in Chromatin Remodeling and Disease Development, Nashwa El Hadidy and Vladimir N. Uversky

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Molecular Dynamics Analysis of the Effects of GTP, GDP and Benzimidazole Derivative on Structural Dynamics of a Cell Division Protein FtsZ from Mycobacterium Tuberculosis, Supriya Hakeem, Inderpal Singh, Preeti Sharma, Anshul Uppal, Yugal Khajuria, Vijeshwar Verma, Vladimir N. Uversky, and Ratna Chandra

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Molecular Docking of Aβ1–40 Peptide and Its Iowa D23N Mutant Using Small Molecule Inhibitors: Possible Mechanisms of Aβ-peptide Inhibition, Rizwan Hasan Khan, Mohammad Khursheed Siddiqi, Vladimir N. Uversky, and Parveen Salahuddin

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Development of a MEL Cell-derived Allograft Mouse Model for Cancer Research, Min Young Kim, Sungwoo Choi, Seol Eui Lee, Ji Sook Kim, Seung Han Son, Young Soo Lim, Bang-Jin Kim, Buom-Yong Ryu, Vladimir N. Uversky, Young Jin Lee, and Chul Geun Kim

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Rational Discovery of Antimetastatic Agents Targeting the Intrinsically Disordered Region of MBD2, Min Young Kim, Insung Na, Ji Sook Kim, Seung Han Son, Sungwoo Choi, Seol Eui Lee, Ji-Hun Kim, Kiseok Jang, Gil Alterovitz, Yu Chen, Arjant van der Vaar, Hyung-Sik Won, Vladimir N. Uversky, and Chul Geun Kim

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Intrinsically Disordered Proteins in Chronic Diseases, Prakash Kulkarni and Vladimir N. Uversky

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Effect of C-terminal His-tag and Purification Routine on the Activity and Structure of the Metalloenzyme, L-alanyl-d-glutamate Peptidase of the Bacteriophage T5, Victor P. Kutyshenko, Galina V. Mikoulinskaia, Sergei V. Chernyshov, Alexander Y. Yegorov, Dmitry A. Prokhorov, and Vladimir N. Uversky

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Structural and Dynamical Order of a Disordered Protein: Molecular Insights Into Conformational Switching of PAGE4 at the Systems Level, Xingcheng Lin, Prakash Kulkarni, Federico Bocci, Nicholas P. Schafer, Susmita Roy, Min-Yeh Tsai, Yanan He, Yihong Chen, Krithika Rajagopalan, Steven M. Mooney, Yu Zeng, Keith Weninger, Alex Grishaev, José N. Onuchic, Herbet Levine, Peter G. Wolynes, Ravi Salgia, Govindan Rangarajan, Vladimir N. Uversky, John Orban, and Mohit Kumar Jolly

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Biophysical Elucidation of Amyloid Fibrillation Inhibition and Prevention of Secondary Nucleation by Cholic Acid: An Unexplored Function of Cholic Acid, Nabeela Majid, Mohammad K. Siddiqi, Asra Nasir Khan, Shabnam Shabnam, Sadia Malik, Aftab Alam, Vladimir N. Uversky, and Rizwan Hasan Khan

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Effect of Cu2+ and Zn2+ Ions on Human Serum Albumin Interaction with Plasma Unsaturated Fatty Acids, Ekaterina L. Nemashkalova, Eugene A. Permyakov, Vladimir N. Uversky, Sergei E. Permyakov, and Ekaterina A. Litus

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Structure Determination by Single-particle Cryo-electron Microscopy: Only the Sky (and Intrinsic Disorder) is the Limit, Emeka Nwanochie and Vladimir N. Uversky

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Introduction to Intrinsically Disordered Proteins and Regions, Christopher J. Oldfield, Vladimir N. Uversky, A. Keith Dunker, and Lukasz Kurgan

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Perturbation of Water Structure by Water-polymer Interactions Probed by FTIR and Polarized Raman Spectroscopy, Jessica Pavelec, David DiGuiseppi, Boris Y. Zavlavsky, Vladimir N. Uversky, and Reinhard Schweitzer-Stenner

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Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases, Orville A. Pemberton, Priyadarshini Jaishankar, Afroza Akhtar, Jessie L. Adams, Lindsey N. Shaw, Adam R. Renslo, and Yu Chen

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Analyzing the Structural and Functional Roles of Residues from the ‘black’ and ‘gray’ Clusters of Human S100P Protein, Maria E. Permyakova, Sergei E. Permyakov, Alexei S. Kazakov, Alexander I. Denesyuk, Konstantin Denessiouk, Vladimir N. Uversky, and Eugene A. Permyakov

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Experimental Insight Into the Structural and Functional Roles of the ‘Black’ and ‘Gray’ Clusters in Recoverin, a Calcium Binding Protein with Four EF-Hand Motifs, Sergei E. Permyakov, Alisa S. Vologzhannikova, Ekaterina L. Nemashkalova, Alexei S. Kazakov, Alexander I. Denesyuk, Konstantin Denessiouk, Viktoriia E. Baksheeva, Andrey A. Zamyatnin Jr., Eugene Yu. Zernii, Vladimir N. Uversky, and Eugene A. Permyakov

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Bioinformatics Analysis of Dysfunctional (Mutated) Proteins of Cardiac Ion Channels Underlying the Brugada Syndrome, Carlos Polanco, Manlio F. Márquez, Vladimir N. Uversky, Thomas Buhse, and Miquel Estrada

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Bioinformatics haracterisation of the (mutated) Proteins Related to Andersen–Tawil Syndrome, Carlos Polanco, Vladimir N. Uversky, Manlio F. Márquez, Thomas Buhse, Miguel Arias Estrada, and Alberto Huberman

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Characterization of an Extensive Interface on Vitronectin for Binding to Plasminogen Activator Inhibitor-1: Adoption of Structure in an Intrinsically Disordered Region, Letitia O. Puster, Christopher B. Stanley, Vladimir N. Uversky, Joseph E. Curtis, Susan Krueger, Yuzhuo Chu, and Cynthia B. Peterson

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Structural Disorder in the Proteome and Interactome of Alkhurma Virus (ALKV), Elrashdy M. Redwan, Abdullah A. AlJaddawi, and Vladimir N. Uversky

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IFI16, a Nuclear Innate Immune DNA Sensor, Mediates Epigenetic Silencing of Herpesvirus Genomes by its Association with H3K9 methyltransferases SUV39H1 and GLP, Arunava Roy, Anandita Ghosh, Binod Kumar, and Bala Chandran

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Stabilizing Proteins to Prevent Conformational Changes Required for Amyloid Fibril Formation, Mohammad Khursheed Siddiqi, Parvez Alam, Sadia Malik, Nabeela Majid, Sumit Kumar Chaturvedi, Sudeepa Rajan, Mohd Rehan Ajmal, Mohsin Vahid Khan, Vladimir N. Uversky, and Rizwan Hasan Khan

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5-Aminolevulinate Synthase Catalysis: The Catcher in Heme Biosynthesis, Bosko M. Stojanovski, Gregory A. Hunter, Insung Na, Vladimir N. Uversky, Rays H.Y. Jiang, and Gloria C. Ferreira

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Stochasticity of Biological Soft Matter: Emerging Concepts in Intrinsically Disordered Proteins and Biological Phase Separation, Konstantin K. Turoverov, Irina M. Kuznetsova, Alexander V. Fonin, April L. Darling, Boris Y. Zaslavsky, and Vladimir N. Uversky

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Intrinsically Disordered Proteins and Their “Mysterious” (Meta)Physics, Vladimir N. Uversky

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Protein Intrinsic Disorder and Structure-function Continuum, Vladimir N. Uversky

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Supramolecular Fuzziness of Intracellular Liquid Droplets: Liquid–liquid Phase Transitions, Membrane-less Organelles, and Intrinsic Disorder, Vladimir N. Uversky

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Torches, Candles, Lamps, Lanterns, Flashlights, Spotlights, Night Vision Goggles… You Need Them All to See in Darkness, Vladimir N. Uversky

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Life in Phases: Intra- and Inter- Molecular Phase Transitions in Protein Solutions, Vladimir N. Uversky and Alexey V. Finkelstein

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On the Need to Develop Guidelines for Characterizing and Reporting Intrinsic Disorder in Proteins, Michael Vincent, Vladimir N. Uversky, and Santiago Schnell

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Effects of His-tags on Physical Properties of Parvalbumins, Alisa A. Vologzhannikova, Polina A. Khorn, Alexei S. Kazakov, Eugene A. Permyakov, Vladimir N. Uversky, and Sergei E. Permyakov

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Small Heat Shock Proteins, Big Impact on Protein Aggregation in Neurodegenerative Disease, Jack M. Webster, April L. Darling, Vladimir N. Uversky, and Laura J. Blair

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Differential Long-term Regulation of TAS2R14 by Structurally Distinct Agonists, Jung A. Woo, Maria Castaño, Ashley Goss, Donghwa Kim, Eric M. Lewandowski, Yu Chen, and Stephen B. Liggett

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Driving Forces of Liquid–Liquid Phase Separation in Biological Systems, Boris Y. Zaslavsky, Luisa A. Ferreira, and Vladimir N. Uversky

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Cwp22, a Novel Peptidoglycan Cross-linking Enzyme, Plays Pleiotropic Roles in Clostridioides Difficile, Duolong Zhu, Jessica Bullock, Yongqun He, and Xingmin Sun

Submissions from 2018

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Chemical Modifications of Insulin: Finding a Compromise Between Stability and Pharmaceutical Performance, Mohsen Akbarian, Younes Ghasemi, Vladimir N. Uversky, and Reza Yousefi

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Structure–Function Relationships in the Oligomeric NADPH-Dependent Assimilatory Sulfite Reductase, Isabel Askenasy, Daniel T. Murray, Rachel M. Andrews, Vladimir N. Uversky, Huan He, and M. Elizabeth Stroupe

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Neurodegenerative Diseases as Protein Folding Disorders, Jeremy D. Baker, Jack M. Webster, Lindsey B. Shelton, John Koren III, Vladimir N. Uversky, Laura J. Blair, and Chad A. Dickey

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Born This Way: Using Intrinsic Disorder to Map the Connections Between SLITRKs, TSHR, and Male Sexual Orientation, Tara Basavanhally, Renée Fonseca, and Vladimir N. Uversky

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Not All AMLETs Are Made Equal: Complexes of Cow and Camel Α-lactalbumin with Oleic Acid Show Different Structure and Stability, Leonid Breydo, Hussein A. Almehdar, Esmail M. El-Fakharany, Elrashdy M. Redwan, and Vladimir N. Uversky

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Insights into the Molecular Mechanisms of Alzheimer’s and Parkinson’s Diseases with Molecular Simulations: Understanding the Roles of Artificial and Pathological Missense Mutations in Intrinsically Disordered Proteins Related to Pathology, Orkid Coskuner-Weber and Vladimir N. Uversky

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Intrinsically Disordered Proteome of Human Membrane-Less Organelles, April L. Darling, Yun Liu, Christopher J. Oldfield, and Vladimir N. Uversky

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Intrinsic Disorder and Posttranslational Modifications: The Darker Side of the Biological Dark Matter, April L. Darling and Vladimir N. Uversky

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On the Relationship Between the Conserved ‘black’ and ‘gray’ Structural Clusters and Intrinsic Disorder in Parvalbumins, Eugenia I. Deryusheva, Alexander I. Denesyuk, Konstantin Denessiouk, Vladimir N. Uversky, Sergei E. Permyakov, and Eugene A. Permyakov

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Trifunctional High-Throughput Screen Identifies Promising Scaffold To Inhibit Grp94 and Treat Myocilin-Associated Glaucoma, Dustin J. E. Huard, Vincent M. Crowley, Yuhong Du, Ricardo A. Cordova, Zheying Sun, Moya O. Tomlin, Chad A. Dickey, John Koren, Laura Blair, Haian Fu, Brian S. J. Blagg, and Raquel L. Lieberman

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Virucidal Activity of Cell-penetrating Peptides of Viral Origin, Nawal Abd El-Baky, Vladimir N. Uversky, and Elrashdy M. Redwan

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The Use of Human, Bovine, and Camel Milk Albumins in Anticancer Complexes with Oleic Acid, Esmail M. El-Fakharany, Marwa M. Abu-Serie, Ekaterina A. Litus, Sergei E. Permyakov, Eugene A. Permyakov, Vladimir N. Uversky, and Elrashdy M. Redwan

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Structural Impact of Phosphorylation and Dielectric Constant Variation on Synaptotagmin’s IDR, Michael E. Fealey, Benjamin P. Binder, Vladimir N. Uversky, Anne Hinderliter, and David D. Thomas

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Modified Binodal Model Describes Phase Separation in Aqueous Two-phase Systems in Terms of the Effects of Phase-forming Components on the Solvent Features of Water, L.A. Ferreira, Vladimir N. Uversky, and B.Y. Zaslavsky

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Effect of Human Heat Shock Protein HspB6 on the Solvent Features of Water in Aqueous Solutions, Luisa A. Ferreira, Nikolai B. Gusev, Vladimir N. Uversky, and Boris Y. Zaslavsky

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Phase Equilibria, Solvent Properties, and Protein Partitioning in Aqueous Polyethylene Glycol-600-trimethylamine N-oxide and Polyethylene Glycol-600-choline Chloride Two-phase Systems, Luisa A. Ferreira, Vladimir N. Uversky, and Boris Y. Zaslavsky

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Effect of an Intrinsically Disordered Plant Stress Protein on the Properties of Water, Luisa A. Ferreira, Alicyia Walczyk Mooradally, Boris Zaslavsky, Vladimir N. Uversky, and Steffen P. Graether

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Elucidating Feed‑forward Apoptosis Signatures in Breast Cancer Datasets: Higher FOS Expression Associated with a Better Outcome, Diana A. Fisler, Dhiraj Sikaria, John M. Yavorski, Yaping N. Tu, and George Blanck

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Intrinsically Disordered Proteins in Crowded Milieu: When Chaos Prevails Within the Cellular Gumbo, Alexander V. Fonin, April L. Darling, Irina M. Kuznetsova, Konstantin K. Turoverov, and Vladimir N. Uversky

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Oxidative Stress Induces Club Cell Proliferation and Pulmonary Fibrosis in Atp8b1 Mutant Mice, Jutaro Fukumoto, Joseph Leung, Ruan Cox Jr, Alexander Czachor, Prasanna Tamarapu Parthasarathy, Venu Lagishetty, Maria Mandry, Nima Hosseinian, Priyanshi Patel, Brittany Perry, Mason T. Breitzig, Matthew Alleyn, Athena Failla, Young Cho, Andrew J. Cooke, Lakshmi Galam, Ramani Soundararajan, Nirmal Sharma, Richard F. Lockey, and Narasaiah Kolliputi

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Recombinant Fusion Protein Joining E Protein Domain III of Tick-Borne Encephalitis Virus and HSP70 of Yersinia pseudotuberculosis as an Antigen for the TI-complexes, Vasily Golotin, Nina M. Sanina, Ludmila Davydova, Natalia Chopenko, Andrey Mazeika, Manuel Roig, Valery L. Shnyrov, Vladimir N. Uversky, and Eduard Kostetsky

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Arrestins: Structural Disorder Creates Rich Functionality, Vsevolod V. Gurevich, Eugenia V. Gurevich, and Vladimir N. Uversky

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Taxonomic Landscape of the Dark Proteomes: Whole-Proteome Scale Interplay Between Structural Darkness, Intrinsic Disorder, and Crystallization Propensity, Gang Hu, Kui Wang, Jiangning Song, Vladimir N. Uversky, and Lukasz Kurgan

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Potential Functions of LEA Proteins from the Brine Shrimp Artemia Franciscana – Anhydrobiosis Meets Bioinformatics, Brett Janis, Vladimir N. Uversky, and Michael A. Menze

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Intrinsically Disordered Proteins and the Janus Challenge, Prakash Kulkarni and Vladimir N. Uversky

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Intrinsically Disordered Proteins: The Dark Horse of the Dark Proteome, Prakash Kulkarni and Vladimir N. Uversky

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Characterization of the Virulence of a Non-RT027, Non-RT078 and Binary Toxin-positive Clostridium Difficile Strain Associated with Severe Diarhea, Chunhui Li, Céline Harmanus, Duolong Zhu, Xiujuan Meng, Shaohui Wang, Juping Duan, Sidi Liu, Chenchao Fu, Pengcheng Zhou, Ruisi Liu, Anhua Wu, Ed J. Kuijper, Wiep Klaas Smits, Lei Fu, and Xingmin Sun

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Intrinsically Disordered Regions in Serum Albumin: What Are They For?, Ekaterina A. Litus, Sergei E. Permyakov, Vladimir N. Uversky, and Eugene A. Permyakov

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Functionally Aberrant Mutant KCNQ1 With Intermediate Heterozygous and Homozygous Phenotypes, Zhenning Liu, Renjian Zheng, Michael J. Grushko, Vladimir N. Uversky, and Thomas V. McDonald

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A Statistical Approach to Detect Intrinsically Disordered Proteins Associated with Uterine Leiomyoma, Ujjwal Maulik, Vladimir N. Uversky, and Sagnik Sen

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Dissecting Physical Structure of Calreticulin, an Intrinsically Disordered Ca2+-buffering Chaperone from Endoplasmic Reticulum, Anna Rita Migliaccio and Vladimir N. Uversky

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Molecular Recognition Features in Zika Virus Proteome, Pushpendra Mani Mishra, Vladimir N. Uversky, and Rajanish Giri

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Anti-Correlation Between the Dynamics of the Active Site Loop and C-Terminal Tail in Relation to the Homodimer Asymmetry of the Mouse Erythroid 5-Aminolevulinate Synthase, Insung Na, Dominique Catena, Min J. Kong, Gloria C. Ferreira, and Vladimir N. Uversky

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Molecular Dynamics Analysis of the Structural and Dynamic Properties of the Functionally Enhanced Hepta-variant of Mouse 5-aminolevulinate Synthase, Insung Na, Shelly DeForte, Bosko M. Stojanovski, Gloria C. Ferreira, and Vladimir N. Uversky

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Predicting Functions of Disordered Proteins with MoRFpred, Christopher J. Oldfield, Vladimir N. Uversky, and Lukasz Kurgan

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Flexibility of the Sec13/31 Cage is Influenced by the Sec31 C-terminal Disordered Domain, Mohammadreza Paraan, Nilakshee Bhattacharya, Vladimir N. Uversky, and Scott M. Stagg

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Alpha-synuclein Inhibits Snx3–retromer-mediated Retrograde Recycling of Iron Transporters in S. cerevisiae and C. elegans Models of Parkinson’s Disease, Dhaval Patel, Chuan Xu, Sureshbabu Nagarajan, Zhengchang Liu, Wayne O. Hemphill, Runhua Shi, Vladimir N. Uversky, Guy A. Caldwell, Kim A. Caldwell, and Stephan N. Witt

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Design, Synthesis, and Characterization of a Fluorescence Polarization Pan-BET Bromodomain Probe, Carolyn N. Paulson, Xianghong Guan, Alex M. Ayoub, Alice Chan, Rezaul M. Karim, William C. K. Pomerantz, Ernst Schonbrunn, Gunda I. Georg, and Jon E. Hawkinson

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Comprehensive Analysis of the Roles of ‘black’ and ‘gray’ Clusters in Structure and Function of Rat Β-parvalbumin, Sergei E. Permyakov, Alisa A. Vologzhannikova, Polina A. Khorn, Marina P. Shevelyova, Alexei S. Kazakov, Victor I. Emelyanenko, Alexander I. Denesyuk, Konstantin Denessiouk, Vladimir N. Uversky, and Eugene A. Permyakov

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On the Regularities of the Polar Profiles of Proteins Related to Ebola Virus Infection and Their Functional Domains, Carlos Polanco, José Lino Samaniego Mendoza, Thomas Buhse, Vladimir N. Uversky, Ingrid Paola Bañuelos Chao, Marcela Angola Bañuelos Cedano, Fernando Michel Tavera, Daniel Michel Tavera, Manuel Falconi, and Abelardo Vela Ponce de León

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Adenylyl Cyclase 6 is Required for Maintaining Acid–base Homeostasis, Søren Brandt Poulsen, Caralina Marin De Evsikova, Sathish Kumar Murali, Jeppe Praetorius, Yijuang Chern, Robert A. Fenton, and Timo Rieg