Aminolaevulinic Acid Synthase of Rhodobacter capsulatus: High-resolution Kinetic Investigation of the Structural Basis for Substrate Binding and Catalysis

Authors

Anna-Lena Kaufholz, Technical University of Braunschweig
Gregory A. Hunter, University of South Florida
Gloria C. Ferreira, University of South FloridaFollow
Thomas Lendrihas, University of South Florida
Vanessa Hering, Technical University of Braunschweig
Gunhild Layer, University of Braunschweig
Martina Jahn, University of Braunschweig
Dieter Jahn, University of Braunschweig

Document Type

Article

Publication Date

2013

Keywords

5-aminolaevulinic acid synthase (ALAS), haem biosynthesis, quinonoid intermediate formation, steady-state kinetics, stopped-flow spectroscopy

Digital Object Identifier (DOI)

https://doi.org/10.1042/BJ20121041

Was this content written or created while at USF?

Yes

Citation / Publisher Attribution

Biochemical Journal, v. 451, issue 2, p. 205-213

Scholar Commons Citation

Kaufholz, Anna-Lena; Hunter, Gregory A.; Ferreira, Gloria C.; Lendrihas, Thomas; Hering, Vanessa; Layer, Gunhild; Jahn, Martina; and Jahn, Dieter, "Aminolaevulinic Acid Synthase of Rhodobacter capsulatus: High-resolution Kinetic Investigation of the Structural Basis for Substrate Binding and Catalysis" (2013). Molecular Medicine Faculty Publications. 95.
https://digitalcommons.usf.edu/mme_facpub/95