Submissions from 2008
Generation and Characterization of an Attenuated Mutant in a Response Regulator Gene of Francisella tularensis Live Vaccine Strain, Wendy L. Sammons-Jackson, Karen McClelland, Jean N. Manch-Citron, Dennis W. Metzger, Chandra Shekhar Bakshi, Emilio Garcia, Amy Rasley, and Burt E. Anderson
Intrinsically Disordered Human C/EBP Homologous Protein Regulates Biological Activity of Colon Cancer Cells During Calcium Stress, Vinay K. Singh, Ivan Pacheco, Vladimir N. Uversky, Steven P. Smith, R. John Macleod, and Zongchao Jia
Fluorescent Proteins as Biomarkers and Biosensors: Throwing Color Lights on Molecular and Cellular Processes, Olga V. Stepanenko, Vladislav V. Verkhusha, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov
Understanding The Role of Arg96 in Structure and Stability of Green Fluorescent Protein, Olga V. Stepanenko, Vladislav V. Verkhusha, Michail M. Shavlovsky, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov
Thioflavin T as a Molecular Rotor: Fluorescent Properties of Thioflavin T in Solvents with Different Viscosity, Vitali I. Stsiapura, Alexander A. Maskevich, Valery A. Kuzmitsky, Vladimir N. Uversky, Irina M. Kuznetsova, and Konstantin K. Turoverov
Assessing Conservation of Disordered Regions in Proteins, Ágnes Tóth-Petróczy, Bálint Mészáros, István Simon, A. Keith Dunker, Vladimir N. Uversky, and Monika Fuxreiter
Malleable Machines in Transcription Regulation: The Mediator Complex, Ágnes Tóth-Petróczy, Christopher J. Oldfield, István Simon, Yuichiro Takagi, A. Keith Dunker, Vladimir N. Uversky, and Monika Fuxreiter
Amyloidogenesis of Natively Unfolded Proteins, Vladimir N. Uversky
α-synuclein Misfolding and Neurodegenerative Diseases, Vladimir N. Uversky
Intrinsic Disorder in Proteins Associated with Neurodegenerative Diseases, Vladimir N. Uversky
Natively Unfolded Proteins, Vladimir N. Uversky
Protein Folding, Misfolding and Aggregation: Classical Themes and Novel Approaches. Edited by Victor Muñoz., Vladimir N. Uversky
Controlled Chaos, Vladimir N. Uversky and A. Keith Dunker
Intrinsically Disordered Proteins in Human Diseases: Introducing The D2 Concept, Vladimir N. Uversky, Christopher J. Oldfield, and A. Keith Dunker
Hen Egg White Lysozyme Fibrillation: a Deep-uv Resonance Raman Spectroscopic Study, Ming Xu, Vladimir V. Ermolenkov, Vladimir N. Uversky, and Igor K. Lednev
Submissions from 2007
Attachment of Lcrv from Yersinia Pestis at Dual Binding Sites to Human TLR-2 and Human Ifn-γ Receptor, Vyacheslav M. Abramov, Valentin S. Khlebnikov, Anatoly M. Vasiliev, Igor V. Kosarev, Raisa N. Vasilenko, Natalia Kulikova, Anna V. Khodyakova, Valentin I. Evstigneev, Vladimir N. Uversky, Vladimir L. Motin, Georgy B. Smirnov, and Robert R. Brubaker
Expression and Localization of Rgs9-2/gβ5/r7bp Complex In Vivo Is Set by Dynamic Control of Its Constitutive Degradation by Cellular Cysteine Proteases, Garret R. Anderson, Rafael Lujan, Arthur Semenov, Marco Praveton, Ekaterina N. Posokhova, Joseph H. Song, Vladimir N. Uversky, Ching-Kang Chen, Kevin Wickman, and Kirill A. Martemyanov
Mining α-helix-forming Molecular Recognition Features with Cross Species Sequence Alignments, Yugong Cheng, Christopher J. Oldfield, Jingwei Meng, Pedro Romero, Vladimir N. Uversky, and A. Keith Dunker
Analysis of Folded, Partially Folded and Misfolded Proteins with Fluorescent Dyes, Irina M. Kuznetsova, Konstantin K. Turoverov, A. Keith Dunker, and Vladimir N. Uversky
A Computational Investigation of Allostery in The Catabolite Activator Protein, Liwei Li, Vladimir N. Uversky, A. Keith Dunker, and Samy O. Meroueh
Spectral Properties of Thioflavin T in Solvents with Different Dielectric Properties and in a Fibril-incorporated Form, Alexander A. Maskevich, Vitali I. Stsiapura, Valery A. Kuzmitsky, Irina M. Kuznetsova, Olga I. Povarova, Vladimir N. Uversky, and Konstantin K. Turoverov
Multiple Aromatic Side Chains Within a Disordered Structure are Critical for Transcription and Transforming Activity of EWS Family Oncoproteins, King Pan Ng, Gary Potikyan, Rupert O. V. Savene, Christopher T. Denny, Vladimir N. Uversky, and Kevin A. W. Lee
Recoverin as a Redox-sensitive Protein, Sergei E. Permyakov, Aliya A. Nazipova, Alexander I. Denesyuk, Anush G. Bakunts, Dmitry V. Zinchenko, Valery M. Lipkin, Vladimir N. Uversky, and Eugene A. Permyakov
Intrinsic Disorder and Functional Proteomics, Predrag Radivojac, Lilia M. Iakoucheva, Christopher J. Oldfield, Zoran Obradovic, and Vladimir N. Uversky
Disprot: The Database of Disordered Proteins, Megan D. Sickmeier, Justin A. Hamilton, Tanguy LeGall, Vladimir Vacic, Marc S. Cortese, Agnes Tantos, Beata Szabo, Peter Tompa, Jake Chen, Vladimir N. Uversky, Zoran Obradovic, and A. Keith Dunker
Parametric Dependence Method for the Analysis of Protein Folding, Konstantin K. Turoverov, Irina M. Kuznetsova, and Vladimir N Uversky
Neuropathology, Biochemistry, and Biophysics of α-synuclein Aggregation, Vladimir N. Uversky
Multiparametric Approach in Analysis of Protein Structure and Unfolding-refolding Reaction, Vladimir N. Uversky
Size Exclusion Chromatography in Protein Structure Analysis, Vladimir N. Uversky
α-Synuclein Aggregation and Parkinson’s Disease, Vladimir N. Uversky
Understanding Protein Non-folding, Vladimir N. Uversky and A. Keith Dunker
Prediction of Intrinsic Disorder and Its Use in Functional Proteomics, Vladimir N Uversky, Predrag Radivojac, Lilia M. Iakoucheva, Zoran Obradovic, and A. Keith Dunker
Characterization of Molecular Recognition Features, Morfs, and Their Binding Partners, Vladimir Vacic, Christopher J. Oldfield, Amrita Mohan, Predrag Radivojac, Marc S. Cortese, Vladimir N. Uversky, and A. Keith Dunker
Composition Profiler: a Tool for Discovery and Visualization of Amino Acid Composition Differences, Vladimir Vacic, Vladimir N. Uversky, A. Keith Dunker, and Stefano Lonardi
Functional Anthology of Intrinsic Disorder. 3. Ligands, Post-translational Modifications, and Diseases Associated with Intrinsically Disordered Proteins, Hongbo Xie, Slobodan Vucetic, Lilia M. Iakoucheva, Christopher J. Oldfield, A. Keith Dunker, Zoran Obradovic, and Vladimir N. Uversky
Functional Anthology of Intrinsic Disorder. 1. Biological Processes and Functions of Proteins with Long Disordered Regions, Hongbo Xie, Slobodan Vucetic, Lilia M. Iakoucheva, Christopher J. Oldfield, A. Keith Dunker, Vladimir N. Uversky, and Zoran Obradovic
Submissions from 2006
Local Flexibility in Molecular Function Paradigm, Jag Bhalla, Geoffrey B. Storchan, Caitlin M. MacCarthy, Vladimir N. Uversky, and Olga Tcherkasskaya
The Disordered Amino-Terminus of SIMPL Interacts with Members of The 70-kDa Heat-Shock Protein Family, Erin Haag Breese, Vladimir N. Uversky, Millie M. Georgiadis, and Maureen A. Harrington
Rational Drug Design Via Intrinsically Disordered Protein, Yugong Cheng, Tanguy Le Gall, Christopher J. Oldfield, James P. Mueller, Ya-Yue Van, Pedro Romero, Marc S. Cortese, Vladimir N. Uversky, and A. Keith Dunker
Abundance of Intrinsic Disorder in Protein Associated with Cardiovascular Disease, Yugong Cheng, Tanguy LeGall, Christopher J. Oldfield, A. Keith Dunker, and Vladimir N. Uversky
Abundance of Intrinsic Disorder in Protein Associated with Cardiovascular Disease, Yugong Cheng, Tanguy LeGall, Christopher J. Oldfield, A. Keith Dunker, and Vladimir N. Uversky
Conservation of Intrinsic Diconservation of Intrinsic Disorder in Protein Domains and Families: II. Functions of Conserved Disordersorder in Protein Domains and Families: II. Functions of Conserved Disorder, Jessica Walton Chen, Pedro R. Romero, Vladimir N. Uversky, and A. Keith Dunker
Conservation of Intrinsic Disorder in Protein Domains and Families: I. A Database of Conserved Predicted Disordered Regions, Jessica Walton Chen, Pedro R. Romero, Vladimir N. Uversky, and A. Keith Dunker
Conformational Properties of the SDS-Bound State of α-Synuclein Probed by Limited Proteolysis: Unexpected Rigidity of the Acidic C-Terminal Tail, Patrizia Polverino de Laureto, Laura Tosatto, Erica Frare, Oriano Marin, Vladimir N. Uversky, and Angelo Fontana
New Views of Protein Structure: Applications to the Caseins: Protein Structure and Functionality, Harold M. Farrell Jr., Phoebe X. Qi, and Vladimir N. Uversky
New Views of Protein Structure: Implications for Potential New Protein Structure-function Relationships, Harold M. Farrell Jr., Phoebe X. Qi, and Vladimir N. Uversky
Intrinsic Disorder Is a Common Feature of Hub Proteins from Four Eukaryotic Interactomes, Chad Haynes, Christopher J. Oldfield, Fei Ji, Niels Klitgord, Michael E. Cusick, Predrag Radivojac, Vladimir N. Uversky, Mark Vidal, and Lilia M. Iakoucheva
Intrinsic Disorder in The Protein Data Bank, Tanguy LeGall, Pedro R. Romero, Marc S. Cortese, Vladimir N. Uversky, and A. Keith Dunker
Intrinsic Disorder in Transcription Factors, Jiangang Liu, Narayanan B. Perumal, Christopher J. Oldfield, Eric W. Su, Vladimir N. Uversky, and A. Keith Dunker
Nanoimaging for Protein Misfolding and Related Diseases, Yuri L. Lyubchenko, Simon Sherman, Luda S. Shlyakhtenko, and Vladimir N. Uversky
Analysis of Molecular Recognition Features (MoRFs), Amrita Mohan, Christopher J. Oldfield, Predrag Radivojac, Vladimir Vacic, Marc S. Cortese, A. Keith Dunker, and Vladimir N. Uversky
Calmodulin Signaling: Analysis and Prediction of a Disorder-dependent Molecular Recognition, Predrag Radivojac, Slobodan Vucetic, Timothy R. O'Connor, Vladimir N. Uversky, Zoran Obradovic, and A. Keith Dunker
Alternative Splicing in Concert with Protein Intrinsic Disorder Enables Increased Functional Diversity in Multicellular Organisms, Pedro R. Romero, Saima Zaidi, Ya Yin Fang, Vladimir N. Uversky, Predrag Radivojac, Christopher J. Oldfield, Marc S. Cortese, Megan D. Sickmeier, Tanguy LeGall, Zoran Obradovic, and A. Keith Dunker
Modulation of Inhibition of Ferrochelatase by N-methylprotoporphyrin, Zhen Shi and Gloria C. Ferreira
Role of Lysine Versus Arginine in Enzyme Cold-adaptation: Modifying Lysine to Homo-arginine Stabilizes The Cold-adapted α-amylase from Pseudoalteramonas Haloplanktis, Khawar Sohail Siddiqui, Anne Poljak, Michael Guilhaus, David De Francisci, Paul M. G. Curmi, Georges Feller, Salvino D'Amico, Charles Gerday, Vladimir N. Uversky, and Ricardo Cavicchioli
Lipid-binding Activity of Intrinsically Unstructured Cytoplasmic Domains of Multichain Immune Recognition Receptor Signaling Subunits, Alexander B. Sigalov, Dikran A. Aivazian, Vladimir N. Uversky, and Lawrence J. Stern
Structural and Conformational Prerequisites of Amyloidogenesis, Vladimir N Uversky, Ariel Fernández, and Anthony L. Fink
Nanotools for Megaproblems: Probing Protein Misfolding Diseases Using Nanomedicine modus Operandi, Vladimir N. Uversky, Alexander V. Kabanov, and Yuri L. Lyubchenko
Protein Intrinsic Disorder and Human Papillomaviruses: Increased Amount of Disorder in E6 and E7 Oncoproteins from High Risk Hpvs, Vladimir N. Uversky, Ann Roman, Christopher J. Oldfield, and A. Keith Dunker
Submissions from 2005
Early Events in The Fibrillation of Monomeric Insulin, Atta Ahmad, Vladimir N. Uversky, Dongpyo Hong, and Anthony L. Fink
Structure-related Statistical Singularities Along Protein Sequences: A Correlation Study, Mauro Colafranceschi, Alfredo Colosimo, Joseph. P. Zbilut, Vladimir N. Uversky, and Alessandro Giuliani
Uncovering The Unfoldome: Enriching Cell Extracts for Unstructured Proteins by Acid Treatment, Marc S. Cortese, Jason P. Baird, Vladimir N. Uversky, and A. Keith Dunker
Natively Disordered Proteins, Gary W. Daughdrill, Gary J. Pielak, Vladimir N. Uversky, Marc S. Cortese, and A. Keith Dunker
Protein Dissection Enhances The Amyloidogenic Properties of α-lactalbumin, Patrizia Polverino de Laureto, Erica Frare, Francesca Battaglia, Maria F. Mossuto, Vladimir N. Uversky, and Angelo Fontana
The Roles of Intrinsic Disorder in Protein Interaction Networks, A. Keith Dunker, Marc S. Cortese, Pedro R. Romero, Lilia M. Iakoucheva, and Vladimir N. Uversky
Porphyrin-substrate Binding to Murine Ferrochelatase: Effect on the Thermal Stability of the Enzyme, Ricardo Franco, Guangyue Bai, Vesna Prosinecki, Filipa Abrunhosa, Gloria C. Ferreira, and Margarida Bastos
Methionine Oxidation, α-synuclein and Parkinson's Disease, Charles B. Glaser, Ghiam Yamin, Vladimir N. Uversky, and Anthony L. Fink
Domain Coupling in a Multimodular Cellobiohydrolase CbhA From Clostridium Thermocellum, Irina Kataeva, John M. Brewer, Vladimir N. Uversky, and Lars G. Ljungdahl
Improving Solubility Of Shewanella Oneidensis MR-1 And Clostridium Thermocellum JW-20 Proteins Expressed Into Esherichia Coli, Irina Kataeva, Jessie Chang, Hao Xu, Chi-Hao Luan, Jizhong Zhou, Vladimir N. Uversky, Dawei Lin, Peter Horanyi, Z. J. Liu, Lars G. Ljungdahl, John Rose, Ming Luo, and Bi-Cheng Wang
Protein Interactions and Misfolding Analyzed by AFM Force Spectroscopy, Chad McAllister, Mikhail A. Karymov, Yoshiko Kawano, Alexander Y. Lushnikov, Andrew Mikheikin, Vladimir N. Uversky, and Yuri L. Lyubchenko
Agrin Binds α-synuclein and Modulates α-synuclein Fibrillation, I-Hsun Ni, Vladimir N. Uversky, Larissa A. Munishkina, Anthony L. Fink, Willi Halfter, and Gregory J. Cole
Comparing and Combining Predictors of Mostly Disordered Proteins, Christopher J. Oldfield, Yugong Cheng, Marc S. Cortese, Celeste J. Brown, Vladimir N. Uversky, and A. Keith Dunker
Coupled Folding and Binding with α-helix-forming Molecular Recognition Elements, Christopher J. Oldfield, Yugong Cheng, Marc S. Cortese, Pedro R. Romero, Vladimir N. Uversky, and A. Keith Dunker
How to Improve Nature: Study of The Electrostatic Properties of The Surface of α-lactalbumin, Sergei E. Permyakov, George I. Makhatadze, Rikard Owenius, Vladimir N. Uversky, Charles L. Brooks, Eugene A. Permyakov, and Lawrence J. Berliner
Conversion of Human α-lactalbumin to an Apo-like State in The Complexes with Basic Poly-amino Acids: Toward Understanding of The Molecular Mechanism of Antitumor Action of HAMLET, Sergei E. Permyakov, Irina V. Pershikova, Andrei P. Zhadan, John Goers, Anush G. Bakunts, Vladimir N. Uversky, Lawrence J. Berliner, and Eugene A. Permyakov
Assessing Protein Disorder and Induced Folding, Véronique Receveur-Bréchot, Jean-Marie Bourhis, Vladimir N. Uversky, Bruno Canard, and Sonia Longhi
A GLYmmer of Insight Into Fibril Formation, Vladimir N. Uversky
Pathways to Amyloid Fibril Formation: Partially Folded Intermediates in the Fibrillation of Natively Unfolded Proteins, Vladimir N. Uversky and Anthony L. Fink
Showing Your ID: Intrinsic Disorder as an ID for Recognition, Regulation and Cell Signaling, Vladimir N. Uversky, Christopher J. Oldfield, and A. Keith Dunker
Effects of Nitration on The Structure and Aggregation of α-synuclein, Vladimir N. Uversky, Ghiam Yamin, Larissa A. Munishkina, Mikhail A. Karymov, Ian S. Millett, Sebastian Doniach, Yuri L. Lyubchenko, and Anthony L. Fink
Lysozyme Fibrillation: Deep UV Raman Spectroscopic Characterization of Protein Structural Transformation, Ming Xu, Vladimir V. Ermolenkov, Wei He, Vladimir N. Uversky, Laura Fredriksen, and Igor K. Lednev
Forcing Nonamyloidogenic β-synuclein To Fibrillate, Ghiam Yamin, Larissa A. Munishkina, Mikhail A. Karymov, Yuri L. Lyubchenko, Vladimir N. Uversky, and Anthony L. Fink
Submissions from 2004
Stimulation of Insulin Fibrillation by Urea-induced Intermediates, Atta Ahmad, Ian S. Millett, Sebastian Doniach, Vladimir N. Uversky, and Anthony L. Fink
Adenylation-dependent Conformation and Unfolding Pathways of The Nad+-dependent DNA Ligase from The Thermophile thermus Scotoductus, Daphné Georlette, Vinciane Blaise, Fabrice Bouillenne, Benjamin Damien, Sigridur H. Thorbjarnardóttir, Eric Depiereux, Charles Gerday, Vladimir N. Uversky, and Georges Feller
Role of Individual Methionines in The Fibrillation of Methionine-oxidized α-synuclein, Mark J. Hokenson, Vladimir N. Uversky, John Goers, Ghiam Yamin, Larissa A. Munishkina, and Anthony L. Fink
Interactions Between Immunoglobulin-like and Catalytic Modules In Clostridium Thermocellum Cellulosomal Cellobiohydrolase CbhA, Irina Kataeva, Vladimir N. Uversky, John M. Brewer, Florian Schubot, John P. Rose, Bi-Cheng Wang, and Lars G. Ljungdahl
Use of The Phase Diagram Method to Analyze The Protein Unfolding-refolding Reactions: Fishing Out The “Invisible” Intermediates, Irina M. Kuznetsova, Konstantin K. Turoverov, and Vladimir N. Uversky
Rifampicin Inhibits α-synuclein Fibrillation and Disaggregates Fibrils, Jie Li, Rajamani Krishna, Vladimir N. Uversky, and Anthony L. Fink
The Effect of Macromolecular Crowding on Protein Aggregation and Amyloid Fibril Formation, Larissa A. Munishkina, Elisa M. Cooper, Vladimir N. Uversky, and Anthony L. Fink
Conformational Prerequisites for Formation of Amyloid Fibrils from Histones, Larissa A. Munishkina, Anthony L. Fink, and Vladimir N. Uversky
Role of Protein−water Interactions and Electrostatics in α-synuclein Fibril Formation, Larissa A. Munishkina, Jeremy Henriquez, Vladimir N. Uversky, and Anthony L. Fink
No Need To Be HAMLET Or BAMLET To Interact with Histones: Binding of Monomeric α-lactalbumin to Histones and Basic Poly-amino Acids, Sergei E. Permyakov, Irina V. Pershikova, Tatyana I. Khokhlova, Vladimir N. Uversky, and Eugene A. Permyakov
Comparative Studies on The Structure and Stability of Fluorescent Proteins EGFP, Zfp506, Mrfp1, “Dimer2”, and Dsred1, Olga V. Stepanenko, Vladislav V. Verkhusha, Alexei S. Kazakov, Michail M. Shavlovsky, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov
Neurotoxicant-induced Animal Models of Parkinson’s Disease: Understanding The Role of Rotenone, Maneb and Paraquat in Neurodegeneration, Vladimir N. Uversky
Conformational Constraints for Amyloid Fibrillation: The Importance of Being Unfolded, Vladimir N. Uversky and Anthony L. Fink
Number of Aβ Inoculations in APP+PS1 Transgenic Mice Influences Antibody Titers, Microglial Activation, and Congophilic Plaque Levels, Donna M. Wilcock, Marcia N. Gordon, Kenneth E. Ugen, Paul E. Gottschall, Giovanni DiCarlo, Chad Dickey, Kristal W. Boyett, Paul T. Jantzen, Karen E. Connor, Jason Melachrino, John Hardy, and David Morgan
Charge and Hydrophobicity Patterning Along The Sequence Predicts The Folding Mechanism and Aggregation of Proteins: A Computational Approach, Joseph. P. Zbilut, Alessandro Giuliani, Alfredo Colosimo, Julie C. Mitchell, Mauro Colafranceschi, Norbert Marwan, Charles L. Webber Jr., and Vladimir N. Uversky
Submissions from 2003
Partially Folded Intermediates in Insulin Fibrillation, Atta Ahmad, Ian S. Millett, Sebastian Doniach, Vladimir N. Uversky, and Anthony L. Fink
Disorder in The Nuclear Pore Complex: The FG Repeat Regions of Nucleoporins are Natively Unfolded, Daniel P. Denning, Samir Patel, Vladimir N. Uversky, Anthony L. Fink, and Michael F. Rexach
Cofactor Binding Modulates The Conformational Stabilities and Unfolding Patterns of Nad+-dependent DNA Ligases from escherichia Coli and thermus Scotoductus, Daphné Georlette, Vinciane Blaise, Christophe Dohmen, Fabrice Bouillenne, Benjamin Damien, Eric Depiereux, Charles Gerday, Vladimir N. Uversky, and Georges Feller
