Submissions from 2009
Neuropathology and Neurochemistry of Parkinson’s Disease: The Never-ending Story Or The Story with No Beginning?, Vladimir N. Uversky
The Mysterious Unfoldome: Structureless, Underappreciated, Yet Vital Part of Any Given Proteome, Vladimir N. Uversky
Biophysics of Parkinson's Disease: Structure and Aggregation of α- Synuclein, Vladimir N. Uversky and David Eliezer
Intrinsically Disordered Proteins and Their Recognition Functions, Vladimir N. Uversky, Monika Fuxreiter, Christopher J. Oldfield, A. Keith Dunker, and Peter Tompa
Unfoldomics of Human Diseases: Linking Protein Intrinsic Disorder with Diseases, Vladimir N. Uversky, Christopher J. Oldfield, Uros Midic, Hongbo Xie, Bin Xue, Slobodan Vucetic, Lilia M. Iakoucheva, Zoran Obradovic, and A. Keith Dunker
Analysis of Structured and Intrinsically Disordered Regions of Transmembrane Proteins, Bin Xue, Liwei Li, Samy O. Meroueh, Vladimir N. Uversky, and A. Keith Dunker
CDF It All: Consensus Prediction of Intrinsically Disordered Proteins Based on Various Cumulative Distribution Functions, Bin Xue, Christopher J. Oldfield, A. Keith Dunker, and Vladimir N. Uversky
At Low Concentrations, 3,4-dihydroxyphenylacetic Acid (DOPAC) Binds Non-covalently to α-synuclein and Prevents Its Fibrillation, Wenbo Zhou, Amy Gallagher, Dong-Pyo Hong, Chunmei Long, Anthony L. Fink, and Vladimir N. Uversky
Submissions from 2008
Interaction of Yersinia pestis Virulence Factors with IL-1R/TLR Recognition System, Vyacheslav M. Abramov, Valentin S. Khlebnikov, Anatoly M. Vasiliev, Igor V. Kosarev, Raisa N. Vasilenko, Nataly L. Kulikova, Vladimir L. Motin, Georgy B. Smirnov, Valentin I. Evstigneev, Nicolay N. Karkischenko, Vladimir N. Uversky, and Robert R. Brubaker
Top-idp-scale: A New Amino Acid Scale Measuring Propensity for Intrinsic Disorder, Andrew Campen, Ryan M. Williams, Celeste J. Brown, Jingwei Meng, Vladimir N. Uversky, and A. Keith Dunker
Suppression of Dendritic Cell Activation by Anthrax Lethal Toxin and Edema Toxin Depends on Multiple Factors Including Cell Source, Stimulus Used, and Function Tested, Ping-Jen Chou, Catherine A. Newton, Izabella Perkins, Herman Friedman, and Thomas W. Klein
Intrinsic Disorder in Scaffold Proteins: Getting More from Less, Marc S. Cortese, Vladimir N. Uversky, and A. Keith Dunker
Prevalence of Intrinsic Disorder in The Intracellular Region of Human Single-pass Type I Proteins: The Case of The Notch Ligand Delta-4, Alfredo De Biasio, Corrado Guarnaccia, Matija Popovic, Vladimir N. Uversky, Alessandro Pintar, and Sándor Pongor
The Unfoldomics Decade: an Update on Intrinsically Disordered Proteins, A. Keith Dunker, Christopher J. Oldfield, Jingwei Meng, Pedro Romero, Jack Y. Yang, Jessica Walton Chen, Vladimir Vacic, Zoran Obradovic, and Vladimir N. Uversky
Function and Structure of Inherently Disordered Proteins, A. Keith Dunker, Israel Silman, Vladimir N. Uversky, and Joel Sussman
Signal Transduction Via Unstructured Protein Conduits, A. Keith Dunker and Vladimir N. Uversky
Structure–function Analysis of Knr4/Smi1, a Newly Member of Intrinsically Disordered Proteins Family, Indispensable in The Absence of a Functional PKC1–SLT2 Pathway in Saccharomyces Cerevisiae, Fabien Durand, Adilia Dagkessamanskaia, Hélène Martin-Yken, Marc Graille, Herman Van Tilbeurgh, Vladimir N. Uversky, and Jean Marie Francois
Malleable Machines Take Shape in Eukaryotic Transcriptional Regulation, Monika Fuxreiter, Peter Tompa, István Simon, Vladimir N. Uversky, Jeffrey C. Hansen, and Francisco J. Asturias
Protein Intrinsic Disorder Toolbox for Comparative Analysis of Viral Proteins, Gerard Kian-Meng Goh, A. Keith Dunker, and Vladimir N. Uversky
Structural Characteristics of α-synuclein Oligomers Stabilized by The Flavonoid Baicalein, Dong-Pyo Hong, Anthony L. Fink, and Vladimir N. Uversky
Effect of Methionine Oxidation on The Structural Properties, Conformational Stability, and Aggregation of Immunoglobulin Light Chain LEN, Dongmei Hu, Zhijie Qin, Bin Xue, Anthony L. Fink, and Vladimir N. Uversky
A Comparative Analysis of Viral Matrix Proteins Using Disorder Predictors, Gerard Kian-Meng Goh, A. Keith Dunker, and Vladimir N. Uversky
The Effect of Membranes on The In Vitro Fibrillation of an Amyloidogenic Light-chain Variable-domain SMA, Xiaoyun Meng, Anthony L. Fink, and Vladimir N. Uversky
Intrinsic Disorder in Pathogenic and Non-pathogenic Microbes: Discovering and Analyzing The Unfoldomes of Early-branching Eukaryotes, Amrita Mohan, William J. Sullivan Jr, Predrag Radivojac, A. Keith Dunker, and Vladimir N. Uversky
Guiding Protein Aggregation with Macromolecular Crowding, Larissa A. Munishkina, Atta Ahmad, Anthony L. Fink, and Vladimir N. Uversky
Concerted Action of Metals and Macromolecular Crowding on The Fibrillation of α-synuclein, Larissa A. Munishkina, Anthony L. Fink, and Vladimir N. Uversky
Flexible Nets: Disorder and Induced Fit in The Associations of P53 and 14-3-3 with Their Partners, Christopher J. Oldfield, Jingwei Meng, Jack Y. Yang, Mary Qu Yang, Vladimir N. Uversky, and A. Keith Dunker
Protein Disorder Is Positively Correlated with Gene Expression In Escherichia Coli, Oleg Paliy, Shawn M. Gargac, Yugong Cheng, Vladimir N. Uversky, and A. Keith Dunker
Apo-parvalbumin as an Intrinsically Disordered Protein, Sergei E. Permyakov, Anush G. Bakunts, Alexander I. Denesyuk, Ekaterina L. Knyazeva, Vladimir N. Uversky, and Eugene A. Permyakov
Dynamics of Oligomer Formation by Denatured Carbonic Anhydrase II, Dmitry A. Prokhorov, Maria A. Timchenko, Vladimir N. Uversky, Vladimir S. Khristoforov, Hiroshi Kihara, Kazumoto Kimura, and Victor P. Kutyshenko
Potato Virus A Genome-linked Protein Vpg is an Intrinsically Disordered Molten Globule-like Protein with a Hydrophobic Core, Kimmo I. Rantalainen, Vladimir N. Uversky, Perttu Permi, Nisse Kalkkinen, A. Keith Dunker, and Kristiina Mäkinen
Short Linear Motifs Recognized by SH2, SH3 and Ser/thr Kinase Domains are Conserved in Disordered Protein Regions, Siyun Ren, Vladimir N. Uversky, Zhengjun Chen, A. Keith Dunker, and Zoran Obradovic
Generation and Characterization of an Attenuated Mutant in a Response Regulator Gene of Francisella tularensis Live Vaccine Strain, Wendy L. Sammons-Jackson, Karen McClelland, Jean N. Manch-Citron, Dennis W. Metzger, Chandra Shekhar Bakshi, Emilio Garcia, Amy Rasley, and Burt E. Anderson
Intrinsically Disordered Human C/EBP Homologous Protein Regulates Biological Activity of Colon Cancer Cells During Calcium Stress, Vinay K. Singh, Ivan Pacheco, Vladimir N. Uversky, Steven P. Smith, R. John Macleod, and Zongchao Jia
Fluorescent Proteins as Biomarkers and Biosensors: Throwing Color Lights on Molecular and Cellular Processes, Olga V. Stepanenko, Vladislav V. Verkhusha, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov
Understanding The Role of Arg96 in Structure and Stability of Green Fluorescent Protein, Olga V. Stepanenko, Vladislav V. Verkhusha, Michail M. Shavlovsky, Irina M. Kuznetsova, Vladimir N. Uversky, and Konstantin K. Turoverov
Thioflavin T as a Molecular Rotor: Fluorescent Properties of Thioflavin T in Solvents with Different Viscosity, Vitali I. Stsiapura, Alexander A. Maskevich, Valery A. Kuzmitsky, Vladimir N. Uversky, Irina M. Kuznetsova, and Konstantin K. Turoverov
Assessing Conservation of Disordered Regions in Proteins, Ágnes Tóth-Petróczy, Bálint Mészáros, István Simon, A. Keith Dunker, Vladimir N. Uversky, and Monika Fuxreiter
Malleable Machines in Transcription Regulation: The Mediator Complex, Ágnes Tóth-Petróczy, Christopher J. Oldfield, István Simon, Yuichiro Takagi, A. Keith Dunker, Vladimir N. Uversky, and Monika Fuxreiter
Amyloidogenesis of Natively Unfolded Proteins, Vladimir N. Uversky
α-synuclein Misfolding and Neurodegenerative Diseases, Vladimir N. Uversky
Intrinsic Disorder in Proteins Associated with Neurodegenerative Diseases, Vladimir N. Uversky
Natively Unfolded Proteins, Vladimir N. Uversky
Protein Folding, Misfolding and Aggregation: Classical Themes and Novel Approaches. Edited by Victor Muñoz., Vladimir N. Uversky
Controlled Chaos, Vladimir N. Uversky and A. Keith Dunker
Intrinsically Disordered Proteins in Human Diseases: Introducing The D2 Concept, Vladimir N. Uversky, Christopher J. Oldfield, and A. Keith Dunker
Hen Egg White Lysozyme Fibrillation: a Deep-uv Resonance Raman Spectroscopic Study, Ming Xu, Vladimir V. Ermolenkov, Vladimir N. Uversky, and Igor K. Lednev
Submissions from 2007
Attachment of Lcrv from Yersinia Pestis at Dual Binding Sites to Human TLR-2 and Human Ifn-γ Receptor, Vyacheslav M. Abramov, Valentin S. Khlebnikov, Anatoly M. Vasiliev, Igor V. Kosarev, Raisa N. Vasilenko, Natalia Kulikova, Anna V. Khodyakova, Valentin I. Evstigneev, Vladimir N. Uversky, Vladimir L. Motin, Georgy B. Smirnov, and Robert R. Brubaker
Expression and Localization of Rgs9-2/gβ5/r7bp Complex In Vivo Is Set by Dynamic Control of Its Constitutive Degradation by Cellular Cysteine Proteases, Garret R. Anderson, Rafael Lujan, Arthur Semenov, Marco Praveton, Ekaterina N. Posokhova, Joseph H. Song, Vladimir N. Uversky, Ching-Kang Chen, Kevin Wickman, and Kirill A. Martemyanov
Mining α-helix-forming Molecular Recognition Features with Cross Species Sequence Alignments, Yugong Cheng, Christopher J. Oldfield, Jingwei Meng, Pedro Romero, Vladimir N. Uversky, and A. Keith Dunker
Analysis of Folded, Partially Folded and Misfolded Proteins with Fluorescent Dyes, Irina M. Kuznetsova, Konstantin K. Turoverov, A. Keith Dunker, and Vladimir N. Uversky
A Computational Investigation of Allostery in The Catabolite Activator Protein, Liwei Li, Vladimir N. Uversky, A. Keith Dunker, and Samy O. Meroueh
Spectral Properties of Thioflavin T in Solvents with Different Dielectric Properties and in a Fibril-incorporated Form, Alexander A. Maskevich, Vitali I. Stsiapura, Valery A. Kuzmitsky, Irina M. Kuznetsova, Olga I. Povarova, Vladimir N. Uversky, and Konstantin K. Turoverov
Multiple Aromatic Side Chains Within a Disordered Structure are Critical for Transcription and Transforming Activity of EWS Family Oncoproteins, King Pan Ng, Gary Potikyan, Rupert O. V. Savene, Christopher T. Denny, Vladimir N. Uversky, and Kevin A. W. Lee
Recoverin as a Redox-sensitive Protein, Sergei E. Permyakov, Aliya A. Nazipova, Alexander I. Denesyuk, Anush G. Bakunts, Dmitry V. Zinchenko, Valery M. Lipkin, Vladimir N. Uversky, and Eugene A. Permyakov
Intrinsic Disorder and Functional Proteomics, Predrag Radivojac, Lilia M. Iakoucheva, Christopher J. Oldfield, Zoran Obradovic, and Vladimir N. Uversky
Disprot: The Database of Disordered Proteins, Megan D. Sickmeier, Justin A. Hamilton, Tanguy LeGall, Vladimir Vacic, Marc S. Cortese, Agnes Tantos, Beata Szabo, Peter Tompa, Jake Chen, Vladimir N. Uversky, Zoran Obradovic, and A. Keith Dunker
Parametric Dependence Method for the Analysis of Protein Folding, Konstantin K. Turoverov, Irina M. Kuznetsova, and Vladimir N Uversky
Neuropathology, Biochemistry, and Biophysics of α-synuclein Aggregation, Vladimir N. Uversky
Multiparametric Approach in Analysis of Protein Structure and Unfolding-refolding Reaction, Vladimir N. Uversky
Size Exclusion Chromatography in Protein Structure Analysis, Vladimir N. Uversky
α-Synuclein Aggregation and Parkinson’s Disease, Vladimir N. Uversky
Understanding Protein Non-folding, Vladimir N. Uversky and A. Keith Dunker
Prediction of Intrinsic Disorder and Its Use in Functional Proteomics, Vladimir N Uversky, Predrag Radivojac, Lilia M. Iakoucheva, Zoran Obradovic, and A. Keith Dunker
Characterization of Molecular Recognition Features, Morfs, and Their Binding Partners, Vladimir Vacic, Christopher J. Oldfield, Amrita Mohan, Predrag Radivojac, Marc S. Cortese, Vladimir N. Uversky, and A. Keith Dunker
Composition Profiler: a Tool for Discovery and Visualization of Amino Acid Composition Differences, Vladimir Vacic, Vladimir N. Uversky, A. Keith Dunker, and Stefano Lonardi
Functional Anthology of Intrinsic Disorder. 3. Ligands, Post-translational Modifications, and Diseases Associated with Intrinsically Disordered Proteins, Hongbo Xie, Slobodan Vucetic, Lilia M. Iakoucheva, Christopher J. Oldfield, A. Keith Dunker, Zoran Obradovic, and Vladimir N. Uversky
Functional Anthology of Intrinsic Disorder. 1. Biological Processes and Functions of Proteins with Long Disordered Regions, Hongbo Xie, Slobodan Vucetic, Lilia M. Iakoucheva, Christopher J. Oldfield, A. Keith Dunker, Vladimir N. Uversky, and Zoran Obradovic
Submissions from 2006
Local Flexibility in Molecular Function Paradigm, Jag Bhalla, Geoffrey B. Storchan, Caitlin M. MacCarthy, Vladimir N. Uversky, and Olga Tcherkasskaya
The Disordered Amino-Terminus of SIMPL Interacts with Members of The 70-kDa Heat-Shock Protein Family, Erin Haag Breese, Vladimir N. Uversky, Millie M. Georgiadis, and Maureen A. Harrington
Rational Drug Design Via Intrinsically Disordered Protein, Yugong Cheng, Tanguy Le Gall, Christopher J. Oldfield, James P. Mueller, Ya-Yue Van, Pedro Romero, Marc S. Cortese, Vladimir N. Uversky, and A. Keith Dunker
Abundance of Intrinsic Disorder in Protein Associated with Cardiovascular Disease, Yugong Cheng, Tanguy LeGall, Christopher J. Oldfield, A. Keith Dunker, and Vladimir N. Uversky
Abundance of Intrinsic Disorder in Protein Associated with Cardiovascular Disease, Yugong Cheng, Tanguy LeGall, Christopher J. Oldfield, A. Keith Dunker, and Vladimir N. Uversky
Conservation of Intrinsic Diconservation of Intrinsic Disorder in Protein Domains and Families: II. Functions of Conserved Disordersorder in Protein Domains and Families: II. Functions of Conserved Disorder, Jessica Walton Chen, Pedro R. Romero, Vladimir N. Uversky, and A. Keith Dunker
Conservation of Intrinsic Disorder in Protein Domains and Families: I. A Database of Conserved Predicted Disordered Regions, Jessica Walton Chen, Pedro R. Romero, Vladimir N. Uversky, and A. Keith Dunker
Conformational Properties of the SDS-Bound State of α-Synuclein Probed by Limited Proteolysis: Unexpected Rigidity of the Acidic C-Terminal Tail, Patrizia Polverino de Laureto, Laura Tosatto, Erica Frare, Oriano Marin, Vladimir N. Uversky, and Angelo Fontana
New Views of Protein Structure: Applications to the Caseins: Protein Structure and Functionality, Harold M. Farrell Jr., Phoebe X. Qi, and Vladimir N. Uversky
New Views of Protein Structure: Implications for Potential New Protein Structure-function Relationships, Harold M. Farrell Jr., Phoebe X. Qi, and Vladimir N. Uversky
Intrinsic Disorder Is a Common Feature of Hub Proteins from Four Eukaryotic Interactomes, Chad Haynes, Christopher J. Oldfield, Fei Ji, Niels Klitgord, Michael E. Cusick, Predrag Radivojac, Vladimir N. Uversky, Mark Vidal, and Lilia M. Iakoucheva
Intrinsic Disorder in The Protein Data Bank, Tanguy LeGall, Pedro R. Romero, Marc S. Cortese, Vladimir N. Uversky, and A. Keith Dunker
Intrinsic Disorder in Transcription Factors, Jiangang Liu, Narayanan B. Perumal, Christopher J. Oldfield, Eric W. Su, Vladimir N. Uversky, and A. Keith Dunker
Nanoimaging for Protein Misfolding and Related Diseases, Yuri L. Lyubchenko, Simon Sherman, Luda S. Shlyakhtenko, and Vladimir N. Uversky
Analysis of Molecular Recognition Features (MoRFs), Amrita Mohan, Christopher J. Oldfield, Predrag Radivojac, Vladimir Vacic, Marc S. Cortese, A. Keith Dunker, and Vladimir N. Uversky
Calmodulin Signaling: Analysis and Prediction of a Disorder-dependent Molecular Recognition, Predrag Radivojac, Slobodan Vucetic, Timothy R. O'Connor, Vladimir N. Uversky, Zoran Obradovic, and A. Keith Dunker
Alternative Splicing in Concert with Protein Intrinsic Disorder Enables Increased Functional Diversity in Multicellular Organisms, Pedro R. Romero, Saima Zaidi, Ya Yin Fang, Vladimir N. Uversky, Predrag Radivojac, Christopher J. Oldfield, Marc S. Cortese, Megan D. Sickmeier, Tanguy LeGall, Zoran Obradovic, and A. Keith Dunker
Modulation of Inhibition of Ferrochelatase by N-methylprotoporphyrin, Zhen Shi and Gloria C. Ferreira
Role of Lysine Versus Arginine in Enzyme Cold-adaptation: Modifying Lysine to Homo-arginine Stabilizes The Cold-adapted α-amylase from Pseudoalteramonas Haloplanktis, Khawar Sohail Siddiqui, Anne Poljak, Michael Guilhaus, David De Francisci, Paul M. G. Curmi, Georges Feller, Salvino D'Amico, Charles Gerday, Vladimir N. Uversky, and Ricardo Cavicchioli
Lipid-binding Activity of Intrinsically Unstructured Cytoplasmic Domains of Multichain Immune Recognition Receptor Signaling Subunits, Alexander B. Sigalov, Dikran A. Aivazian, Vladimir N. Uversky, and Lawrence J. Stern
Structural and Conformational Prerequisites of Amyloidogenesis, Vladimir N Uversky, Ariel Fernández, and Anthony L. Fink
Nanotools for Megaproblems: Probing Protein Misfolding Diseases Using Nanomedicine modus Operandi, Vladimir N. Uversky, Alexander V. Kabanov, and Yuri L. Lyubchenko
Protein Intrinsic Disorder and Human Papillomaviruses: Increased Amount of Disorder in E6 and E7 Oncoproteins from High Risk Hpvs, Vladimir N. Uversky, Ann Roman, Christopher J. Oldfield, and A. Keith Dunker
Submissions from 2005
Early Events in The Fibrillation of Monomeric Insulin, Atta Ahmad, Vladimir N. Uversky, Dongpyo Hong, and Anthony L. Fink
Structure-related Statistical Singularities Along Protein Sequences: A Correlation Study, Mauro Colafranceschi, Alfredo Colosimo, Joseph. P. Zbilut, Vladimir N. Uversky, and Alessandro Giuliani
Uncovering The Unfoldome: Enriching Cell Extracts for Unstructured Proteins by Acid Treatment, Marc S. Cortese, Jason P. Baird, Vladimir N. Uversky, and A. Keith Dunker
Natively Disordered Proteins, Gary W. Daughdrill, Gary J. Pielak, Vladimir N. Uversky, Marc S. Cortese, and A. Keith Dunker
Protein Dissection Enhances The Amyloidogenic Properties of α-lactalbumin, Patrizia Polverino de Laureto, Erica Frare, Francesca Battaglia, Maria F. Mossuto, Vladimir N. Uversky, and Angelo Fontana
The Roles of Intrinsic Disorder in Protein Interaction Networks, A. Keith Dunker, Marc S. Cortese, Pedro R. Romero, Lilia M. Iakoucheva, and Vladimir N. Uversky
Porphyrin-substrate Binding to Murine Ferrochelatase: Effect on the Thermal Stability of the Enzyme, Ricardo Franco, Guangyue Bai, Vesna Prosinecki, Filipa Abrunhosa, Gloria C. Ferreira, and Margarida Bastos
Methionine Oxidation, α-synuclein and Parkinson's Disease, Charles B. Glaser, Ghiam Yamin, Vladimir N. Uversky, and Anthony L. Fink
Domain Coupling in a Multimodular Cellobiohydrolase CbhA From Clostridium Thermocellum, Irina Kataeva, John M. Brewer, Vladimir N. Uversky, and Lars G. Ljungdahl
