Theses/Dissertations from 2015
Ikaros Deficiency Leads To An Imbalance in Effector and Regulatory T Cell Homeostasis in Murine Pancreatic Cancer, Nadine D. Nelson
5-Aminolevulinate Synthase: Characterization of the Enzymatic Mechanism, Reaction Selectivity, and Structural Plasticity, Bosko M. Stojanovski
Theses/Dissertations from 2014
Computer-Aided Structure-Based Drug Discovery: CXCL12, P. aeruginosa LpxA, and the Tiam1 PDZ Domain, Emmanuel William Smith
Longitudinal Quantitative Analysis of Gait and Balance in Friedreich's Ataxia, Jeannie B. Stephenson
Theses/Dissertations from 2011
An Observation of Immunological Effect, a Diet Enhanced with Spirulina and Treatment with Fractalkine in Models of Parkinson's Disease, Mibel M. Pabón
Theses/Dissertations from 2010
Splicing Systems for Studying Signaling to the Spliceosome, Hercules S. Apostolatos
Neuroprotection with Anesthetics in Two Models of Cerebral Ischemia, Rafael Eduardo Chaparro Buitrago
Regulatory Mechanism of Myeloid Derived Suppressor Cell Activity, Cesar Alexander Corzo
Characterization of the Role of Nicotine and Delta 9-THC in Modulation of Neuroinflammation, Jared C. Ehrhart
Evaluation of Immunogene Therapy Using a Plasmid Encoding IL-15 Delivered by Electroporation in a 3D Tumor Model and a Mouse Melanoma Model, Bernadette Marrero
N-Glycosylation Modulates Gating and Antibiotic Block of the Human Potassium Channel, hERG1A, Sarah A. Norring
Functional Connectivity and Responses to Chemoreceptor Stimulation of Medullary Ventrolateral Respiratory Column Neurons, Mackenzie M. Ott
Characterization of Cannabinoid Receptor 2 Transcript Expression in B Cells, Tracy Sherwood
Theses/Dissertations from 2009
On the Involvement of the Low-Density Lipoprotein Receptor in the Pathogenesis and Progression of Alzheimer’s Disease, Jose Francisco Abisambra Socarras
Cannabinoids Induce Immunoglobulin Class Switching to IgE in B Lymphocytes, Marisela Agudelo
Characterization of NPRC and its binding partners, Abdel A. Alli
The Role of Neuroinflammation in Regulating the Age-Related Decline in Neurogenesis, Adam D. Bachstetter
Identification and Characterization of Mitochondrial Genome Concatemers in AIDS-Associated Lymphomas and Lymphoma Cell Lines, Felipe Bedoya
Molecular Intervention in Mouse Models of Amyotrophic Lateral Sclerosis and Alzheimer’s Disease – Neuropathology and Behavior, Steven Prescott Bennett
STAT3 Contributes to Resistance Towards BCR-ABL Inhibitors in a Bone Marrow Microenvironment Model of Drug Resistance in Chronic Myeloid Leukemia Cells, Nadine N. Bewry
Thyroid Hormone Regulation of Cholesterol Metabolism, Lindsey R. Boone
Recombinant AAV Gene Therapy and Delivery, Nikisha Christine Carty
Intradermal Delivery of Plasmids Encoding Angiogenic Growth Factors by Electroporation Promotes Wound Healing and Neovascularization, Bernadette Ferraro
Immunomodulatory Effects of Novel Therapies for Stroke, Aaron A. Hall
Modulation of ASIC1a Function by Sigma-1 Receptors: Physiological and Pathophysiological Implications, Yelenis Herrera
Co-Transcriptional Splicing and Functional Role of PKCβ in Insulin-Sensitive L6 Skeletal Muscle Cells and 3T3-L1 Adipocytes, Eden Kleiman
Investigation into the rate-determining step of mammalian heme biosynthesis: Molecular recognition and catalysis in 5-aminolevulinate synthase, Thomas Lendrihas
Glycosylation Modulates Cardiac Excitability by Altering Voltage-Gated Potassium Currents, Tara A. Schwetz
PLP-Dependent α-Oxoamine Synthases: Phylogenetic Analysis, Structural Plasticity, and Structure-Function Studies on 5-Aminolevulinate Synthase, Tracy D. Turbeville
Theses/Dissertations from 2008
The Modulation by Anthrax Toxins of Dendritic Cell Activation, Ping-Jen Chou
Multi-Level Regulation Of Argininosuccinate Synthase: Significance For Endothelial Nitric Oxide Production, Karen Davidowitz Corbin
Pandemic Vibrio parahaemolyticus: Defining Strains Using Molecular Typing and a Growth Advantage at Lower Temperatures, Carisa Renee Davis
The Role of RalA and RalB in Cancer, Samuel C. Falsetti
Monocytes as Gene Therapy Vectors for the Treatment of Alzheimer’s Disease, Lori Ann Lebson
The Role of Extracellular Matrix and Matrix-Degrading Proteases in Neonatal Hypoxic-Ischemic Injury, Christopher C. Leonardo
Immunomodulation As A Potential Therapeutic Approach For Alzheimer’s Disease, William Veljko Nikolic
Flavonoids as Modulators of Amyloid Precursor Protein Metabolism and Alzheimer Disease Pathology, Kavon Rezai-Zadeh
The Role Of Curcumin In Human Dendritic Cell Maturation And Function, Shawna A. Shirley
Theses/Dissertations from 2007
Alternative Targets for the Treatment of Stroke, Craig T. Ajmo Jr.
Integrin Mediated Mechanotransduction in Renal Vascular Smooth Muscle Cells, Lavanya Balasubramanian
Structure-Function Studies of Conserved Sequence Motifs of Cytochrome b5 Reductase:, Louis J. Crowley
Optimization of anti-Abeta antibody therapy, Rachel Anne Karlnoski
Modulation of adult neural plasticity by proteolytic catabolism of lecticans, Joanne Mayer
The role of norepinephrine in learning: Cerebellar motor learning in rats, Daniel A. Paredes
Major tea catechin inhibits dendritic cell maturation in response to microbial stimulation, James L. Rogers
Generation and characterization of an attenuated mutant in a response-regulator gene of Francisella tularensis live vaccine strain (LVS), Wendy L. Sammons
Src kinase inhibitors for the treatment of sarcomas: Cellular and molecular mechanisms of action, Audrey Cathryn Shor
The proteoglycan perlecan regulates long bone growth through interactions with developmental proteins in the growth plate, Simone Marsha-Lee Smith
Functional characterization of roles of histone deacetylases in the regulation of DNA damage response, Zhigang Yuan
Theses/Dissertations from 2006
Regulation of transcription and analysis of drug targets in lymphoma and myeloma cells, Sophia C. E Bolick
B-Raf is an essential component of the mitotic machinery critical for activation of MAPK signaling during mitosis in Xenopus egg extracts, Sergiy I. Borysov
The role of Src homology 2 domain containing 5' inositol phosphatase 1 (SHIP) in hematopoietic cells, Caroline Desponts
Functional topology and regulation of endothelial nitric oxide synthase and associated caveolar components, Brenda R. Flam
Modulation of neural plasticity by the ADAMTSs (a disintegrin and metalloproteinase with thrombospondin motifs), Michelle Grace Hamel
Occupancy and function of the hepatic HMG-CoA reductase promoter, William Raymond Lagor
Cannabinoids suppress dendritic cell-induced T helper cell polarization, Tangying (Lily) Lu
Endothelial cell mediators of angiogenesis in Bartonella henselae infection, Amy M. McCord
Electrogenetherapy of established B16 murine melanoma by using an expression plasmid for HIV-1 viral protein R, Andrea Nicole McCray
Developing culture conditions to study keratocyte phenotypes in vitro, Kurt Musselmann
Heme biosynthesis: structure-activity studies of murine ferrochelatase, Zhen Shi
Theses/Dissertations from 2005
Chromosome Missegregation in Alzheimer’s Disease Caused by Presenilin 1, Debrah I. Boeras
Role of Stat3 in Regulating HIF-1alpha Expression and Tumor Angiogenesis, Jon J. Briggs
Promoting and Preventing Alzheimer’s Disease in a Transgenic Mouse Model: Apolipoprotein E and Environmental Enrichment, David Antonio Costa
Study of the Roles of LRBA in Cancer Cell Proliferation and SHIP-1 in NK Cell Function, Joshua John Gamsby
The Role and Regulation of Argininosuccinate Synthase in Endothelial Function, Bonnie L. Goodwin
Theses/Dissertations from 2001
Regulation of YY1, a Multifunctional Transcription Factor, Ya-Li Yao