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Theses/Dissertations from 2012

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N-Acyl Ciprofloxacins: Synthesis, Antibacterial Activity and Effects on Molecular Loading of Poly(vinyl benzoate) Nanoparticles, Ryan Cormier

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1-deoxy-D-xylulose-5-phosphate Synthase (DXS) Mechanistic Study and its Implication in the Development of Novel Antibiotics and Antimalarials, Sumit Handa

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Chiral BINOL Metal Phosphate/Phosphoric Acid Catalyzed Enantioselective Addition of Phosphorus and Sulfur Nucleophiles to Imines and Epoxides, Gajendrasingh Ingle

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Hierarchy of Supramolecular Synthons in the of Design Multi-Component Crystals, Padmini Kavuru

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Design, Synthesis, Processing, and Thermal Analysis of Nanocomposites with Tunable Properties, Mu Seong Kim

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Development and Optimization of Kinetic Target-Guided Synthesis Approaches Targeting Protein-Protein Interactions of the Bcl-2 Family, Sameer Shamrao Kulkarni

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Design, Synthesis and Evaluation of Novel Diazirine Photolabels with Improved Ambient Light Stability and Fluorous-Based Enrichment Capacity, Arun Babu Kumar

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Enantioselective Brønsted and Lewis Acid-Catalyzed Reaction Methodology: Aziridines as Building Blocks for Catalytic Asymmetric Induction, Shawn E. Larson

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Protein Profiling of Adenine Nucleoside and Nucleotide Analogs Binding Proteins Using N6-Biotinylated-8-azidoadenosine Analogs as Affinity Based Protein Profiling Probes, Shikha Mahajan

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Design and Construction of Functional Metal-Metalloporphyrin Frameworks, Le Meng

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cHYD1 Solution Phase Synthesis Optimization and the Development of a Novel Human Growth Hormone Antagonist and Agonist, Philip Murray

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Development of a Bio-Molecular Fluorescent Probe Used in Kinetic Target-Guided Synthesis for the Identification of Inhibitors of Enzymatic and Protein-Protein Interaction Targets, Katya Pavlova Nacheva

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Design of Novel Inhibitors for Infectious Diseases using Structure-based Drug Design: Virtual Screening, Homology Modeling and Molecular Dynamics, Divya Ramamoorthy

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Use and Development of Computational Tools in Drug Discovery: From Small Molecules to Cyclic Peptides, Daniel Navarrete Santiago

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Molecular Dynamics of the RNA Binding Cavity of Influenza A Non-structural Protein 1 (NS1) RNA Binding Domain, Christi Leigh Whittington

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Asymmetric Intra- and Intermolecular Cyclopropanation by Co(II)- Based Metalloradical Catalysis, Xue Xu

Theses/Dissertations from 2011

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Sol-gel Resorcinarene Sorbent for Capillary Microextraction Coupled to Gas Chromatography, Abdullah Awadh Alhendal

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Synthesis and Characterization of Self-Healing Poly (Carbonate Urethane) Carbon-Nanotube Composites, Roger Wesley Bass

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Guanidines, Amidines and Carbamides as Novel Sigma Receptor Ligands for Post-Stroke Therapeutics, Michelle Yolanda Cortes-Salva

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Lead Discovery and Optimization Strategies Towards the Development of 4(1H)-Quinolones and 1,2,3,4-Tetrahydroacridone Analogs with Antimalarial Activity, Richard Matthew Cross

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Role of Protein Kinase C-iota in Glioblastoma, Shraddha R. Desai

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Synthesis of Small Molecule Inhibitors of Janus Kinase 2, Phosphodiesterase IV, GABAA and NMDA receptors: Investigation of Mcmurry, Mannich and Chemoenzymatic Strategies, Meghanath Gali

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Electronic Structure Characterization of Nanocrystalline Surfaces and Interfaces with Photoemission Spectroscopy, Sebastian Gutmann

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Chemical Investigation of the Antarctic Marine Invertebrates Austrodoris kerguelenensis & Dendrilla membranosa and the Antarctic Red Alga Gigartina skottsbergii, John Alan Maschek

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Natural Product Drug Discovery against Tropical Diseases, Wai Sheung Ma

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Crystal Engineering of Pharmaceutical Cocrystals, Sreya Mukherjee

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Crystal Engineering of Molecular and Ionic Cocrystals, Tien Teng Ong

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Solid-State Synthesis of Imide Ligands for the Self-Assembly of Metal-Organic Materials, Jason Alexander Perman

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Role of Protein Kinase C-iota in Neuroblastoma and the Effect of ICA-1, a Novel Protein Kinase C-iota Inhibitor on the Proliferation and Apoptosis of Neuroblastoma Cells, Prajit P. Pillai

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Synthesis and Antimicrobial Activities of S,S'-Heterosubstituted Disulfides, Praveen Ramaraju

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Probing Molecules in Confined Space, Carissa Marie Vetromile

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Crystal Engineering of Multiple Component Crystal Forms of Active Pharmaceutical Ingredients, David Rudy Weyna

Theses/Dissertations from 2010

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Metal-Organic Materials: From Design Principles to Practical Applications, Mohamed H. Alkordi

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New Peptide-pair Screening Strategy and Peptidylglycine a-Hydroxylating Monooxygenase (PHM) Based Enrichment Method for the Discovery of Novel a-Amidated Peptides, Zhenming An

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Structural Diversity in Crystal Chemistry: Rational Design Strategies Toward the Synthesis of Functional Metal-Organic Materials, Amy J. Cairns

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Use of Model Compounds to Study Potential Removal of Pharmaceuticals Using Octolig®, Wen-shan Chang

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Biosynthesis of Fatty Acid Amides, Emma K. Farrell

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The Design and Synthesis of Functionalized Porphyrins and Their Applications in Group Transfer Reactions, Medicine, and Materials, Kimberly Bliss Fields

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Tracking Chemistry Self-Efficacy and Achievement in a Preparatory Chemistry Course, Carmen Alicia Garcia

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Applications of Molecular Dynamics Techniques and Spectroscopic Theories to Aqueous Interfaces, Anthony Green

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Electric-Field Effects and Interactions of Dye–Polymer Systems, Brent Hilker

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Synthesis of Functionalized Resorcin[4]arene via Click Chemistry, Ali Husain

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Design and Synthesis of Beta-Hairpin Peptidomimetics for Modulating Integrin Mediated Cell Adhesion, Abeta Fibrillogenesis and p53-MDM2 Protein-Protein Interactions, Priyesh Jain

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Design, Synthesis & Biological Activity of Novel Protein Tyrosine Phosphatase (PTP) Mimetics, Sridhar Reddy Kaulagari

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Corrole Synthesis and Catalytic Applications Toward Cobalt(III)-Catalyzed Epoxidation, N-H Insertion, and Cyclopropanation, Chung Sik Kim

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Antarctic Tunicates and Endophytic Fungi: Chemical Investigation and Synthesis, Matthew D. Lebar

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Chemical Investigation of the Antarctic Marine Invertebrates Synoicum adareanum and Artemisina plumosa, Jaime Heimbegner Noguez

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Design, Synthesis and Post-Synthetic Modifications of Functional Metal-Organic Materials, Farid Nouar

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Surface-Bonded Sol-Gel Sorbents for On-Line Hyphenation of Capillary Microextraction with High-Performance Liquid Chromatography, Scott S. Segro

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Photothermal Studies of Carboxymyoglobin, Meagan Small

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Computer Simulation of Metal-Organic Materials, Abraham C. Stern

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Design, Combinatorial Synthesis, and Biological Evaluation of Novel α-Helical Mimetics Based on Functionalized Piperazines as Antagonists of p53/MDM2 Interactions, Melissa Elizabeth Topper

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Refinement of a Chemistry Attitude Measure for College Students, Xiaoying Xu

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Design and Combinatorial Synthesis Approach of Non-peptidic Trimeric Small Molecules Mimicking i, i + 4(3), i + 7 Positions of alpha-Helices, Mingzhou Zhou

Theses/Dissertations from 2009

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Crystal Engineering of Nutraceutical Cocrystals, Dalia A. Aboarayes

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Design and Synthesis of Substituted 1,4-Hydrazine-linked Piperazine-2,5- and 2,6-diones and 2,5-Terpyrimidinylenes as α-Helical Mimetics, Laura Anderson

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Theory and Simulation of Metal-Organic Materials and Biomolecules, Jonathan L. Belof

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The Role of Cocrystals in Solid-State Synthesis of Imides and the Development of Novel Crystalline Forms of Active Pharmaceutical Ingredients, Miranda L. Cheney

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Computer Simulations of Apomyoglobin Folding, Mariangela Dametto

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Productive Whole-Class Discussions: A Qualitative Analysis of Peer Leader Behaviors in General Chemistry, Teresa McClain Eckart

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Germania-Based Sol-Gel Organic-Inorganic Hybrid Coatings for Capillary Microextraction, Li Fang

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Synthesis and characterization of a novel Poly(methyl methacrylate) Composites using Copper-4, 4'- Trimethylenedipyridine Metal-Organic Framework as Fillers, Shisi Liu

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Time-resolved thermodynamics studies of heme signaling proteins and model systems, Audrey Mokdad

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Hierarchical complexity in metal-organic materials: From layers to polyhedra to supermolecular building blocks, John Jackson Perry

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Cocrystals of nutraceuticals: Protocatechuic acid and quercetin, Twarita Anil Pujari

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Synthesis of small molecule inhibitors targeting signal transduction pathways, Divya Ramamoorthy

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Quest Towards the Design and Synthesis of Functional Metal-Organic Materials: A Molecular Building Block Approach, Dorina F. Sava

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N-Acyltyramines as Substrates for Tyrosinase: Enzymatic Lag and Dopamine Precursor, Jacob A. Shafer

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Ionic Liquid-Mediated Sol-Gel Sorbents for Capillary Microextraction and Challenges in Glass Microfabrication, Anne M. Shearrow

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Two Methodologies in Pursuit of the Elucidation of Copper (II)—Centered Bioinorganic Chemistry, William John Wagner

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Enzymatic and Chemical Synthesis of Polyesters and Polycarbonates Derived from LTartaric Acid and Synthesis of Polycaprolactones Initiated by Cavitands, Ruizhi Wu

Theses/Dissertations from 2008

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Toward the Synthesis of Designed Metal-Organic Materials, Jacilynn A. Brant

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Rational Synthesis Toward the Design of Functional Metal-Organic Materials, Jarrod F. Eubank

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N-Acylethanolamines as Novel Alcohol Dehydrogenase 3 Substrates, Milena Ivkovic

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Formal Reasoning and Spatial Ability: A Step towards "Science for All", Bo Jiang

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Crystal Engineering of Flavonoids, Padmini Kavuru

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Application of Pd Catalyzed Alkylation: Synthesis of Bicyclic Furans, Isoxazolines and New Cyclopentane Amino acid Analogs, Pasha Moeenuddin Khan

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Steady State and Theoretical Investigations of Peptidylglycine α-Amidating Monooxygenase (PAM), Edward W. Lowe

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Mechanistic Studies of Peptidylglycine Alpha-Amidating Monooxygenase (PAM), Neil R. McIntyre

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Structural Diversity in Metal-Organic Materials, Gregory J. McManus

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Enantioselective Brønsted Acid-Catalyzed Reaction Methodology Part A: Enantioselective Mannich Reaction Part B: Enantioselective Desymmetrization of meso-Aziridines, Emily Bretherick Rowland

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Enantioselective, Bronsted Acid-Catalyzed Additions of Nitrogen and Carbon Nucleophiles to Imines, Gerald B. Rowland Jr.

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Cobalt(II)-Catalyzed Atom/Group Transfer Reactions: Stereoselective Carbene and Nitrene Transfer Reactions, Joshua V. Ruppel

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Metallopeptides As Model Systems For The Study Of Cu(II)-Dependent Oxidation Chemistry, William Maung Tay

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Development of Novel Biocompatible Hydrogel Coatings for Implantable Glucose Sensors, Chunyan Wang

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Role of Protein Kinase C-iota in Prostate Cancer, Hla Yee Win

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Cysteine Based PNA (CPNA): Design, Synthesis and Application, Sung Wook Yi

Theses/Dissertations from 2007

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Glyconanobiotics: Novel Carbohydrated Nanoparticle Polymers, Thotaha Wijayahewage Sampath Chrysantha Abeylath

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Synthesis of Novel Cysteine Peptide Nucleic Acid (CPNA), Mehul J. Ajmera

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The Bioinorganic Chemistry Of Copper-Containing Systems: From Type-3 Systems Pertinent To Alzheimer’s Disease To Mononuclear Hydrolysis Involved In Biological Development, Giordano Faustini Zimmerer Da Silva

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Development of biocompatible multi-drug conjugated nanoparticles/smart polymer films for biomedicinal applications, Kerriann R. Greenhalgh

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Examining the evolution of phosphagen kinases: A study of a dimeric arginine kinase from sea urchin (Strongylocentrotus purpuratus) eggs, Brenda Christine Held

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Crystallization studies of epigallocatechin gallate, Sheshanka Kesani

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Sol-gel immobilized cyano-polydimethylsiloxane and short chain polyethylene glycol coatings for capillary microextraction coupled to gas chromatography, Sameer M. Kulkarni

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Using in situ click chemistry to modulate protein-protein interactions: Bcl-XL as a case study, Lisa M. Malmgren

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Functionalization of Resorcinarenes and Study of Antimicrobial Activity, Kirankirti Muppalla

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Construction and application of computationally tractable theories on nonlinear spectroscopy, Christine L. Neipert

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Crystal engineering of co-crystals and their relevance to pharmaceutical forms, Tanise R. Shattock

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Physical, kinetic, and immunological studies of monomeric (Periplaneta americana) and dimeric (Isostychopus badonotus) arginine kinases, Brianne Wright-Weber