Theses/Dissertations from 2023
Exploring strain variation and bacteriophage predation in the gut microbiome of Ciona robusta, Celine Grace F. Atkinson
Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression, Janine M. DeBlasi
Thermodynamic frustration of TAD2 and PRR contribute to autoinhibition of p53, Emily Gregory
Utilization of Detonation Nanodiamonds: Nanocarrier for Gene Therapy in Non-Small Cell Lung Cancer, Allan E. Gutierrez
Role of HLA-DRB1 Fucosylation in Anti-Melanoma Immunity, Daniel K. Lester
Targeting BET Proteins Downregulates miR-33a To Promote Synergy with PIM Inhibitors in CMML, Christopher T. Letson
Regulated Intramembrane Proteolysis by M82 Peptidases: The Role of PrsS in the Staphylococcus aureus Stress Response, Baylie M. Schott
Histone Deacetylase 8 is a Novel Therapeutic Target for Mantle Cell Lymphoma and Preserves Natural Killer Cell Cytotoxic Function, January M. Watters
Theses/Dissertations from 2022
Regulation of the Heat Shock Response via Lysine Acetyltransferase CBP-1 and in Neurodegenerative Disease in Caenorhabditis elegans, Lindsey N. Barrett
Determining the Role of Dendritic Cells During Response to Treatment with Paclitaxel/Anti-TIM-3, Alycia Gardner
Cell-free DNA Methylation Signatures in Cancer Detection and Classification, Jinyong Huang
The Role Of Eicosanoid Metabolism in Mammalian Wound Healing and Inflammation, Kenneth D. Maus
A Holistic Investigation of Acidosis in Breast Cancer, Bryce Ordway
Characterizing the Impact of Postharvest Temperature Stress on Polyphenol Profiles of Red and White-Fruited Strawberry Cultivars, Alyssa N. Smith
Theses/Dissertations from 2021
Multifaceted Approach to Understanding Acinetobacter baumannii Biofilm Formation and Drug Resistance, Jessie L. Allen
Cellular And Molecular Alterations Associated with Ovarian and Renal Cancer Pathophysiology, Ravneet Kaur Chhabra
Ecology and diversity of boletes of the southeastern United States, Arian Farid
CircREV1 Expression in Triple-Negative Breast Cancer, Meagan P. Horton
Microbial Dark Matter: Culturing the Uncultured in Search of Novel Chemotaxonomy, Sarah J. Kennedy
The Multifaceted Role of CCAR-1 in the Alternative Splicing and Germline Regulation in Caenorhabditis elegans, Doreen Ikhuva Lugano
Unraveling the Role of Novel G5 Peptidase Family Proteins in Virulence and Cell Envelope Biogenesis of Staphylococcus aureus, Stephanie M. Marroquin
Cytoplasmic Polyadenylation Element Binding Protein 2 Alternative Splicing Regulates HIF1α During Chronic Hypoxia, Emily M. Mayo
Transcriptomic and Functional Investigation of Bacterial Biofilm Formation, Brooke R. Nemec
A Functional Characterization of the Omega (ω) subunit of RNA Polymerase in Staphylococcus aureus, Shrushti B. Patil
The Role Of Cpeb2 Alternative Splicing In TNBC Metastasis, Shaun C. Stevens
Theses/Dissertations from 2020
Understanding the Role of Cereblon in Hematopoiesis Through Structural and Functional Analyses, Afua Adutwumwa Akuffo
To Mid-cell and Beyond: Characterizing the Roles of GpsB and YpsA in Cell Division Regulation in Gram-positive Bacteria, Robert S. Brzozowski
Spatiotemporal Changes of Microbial Community Assemblages and Functions in the Subsurface, Madison C. Davis
New Mechanisms That Regulate DNA Double-Strand Break-Induced Gene Silencing and Genome Integrity, Dante Francis DeAscanis
Regulation of the Heat Shock Response and HSF-1 Nuclear Stress Bodies in C. elegans, Andrew Deonarine
New Mechanisms that Control FACT Histone Chaperone and Transcription-mediated Genome Stability, Angelo Vincenzo de Vivo Diaz
Targeting the ESKAPE Pathogens by Botanical and Microbial Approaches, Emily Dilandro
Succession in native groundwater microbial communities in response to effluent wastewater, Chelsea M. Dinon
Role of ceramide-1 phosphate in regulation of sphingolipid and eicosanoid metabolism in lung epithelial cells, Brittany A. Dudley
Allosteric Control of Proteins: New Methods and Mechanisms, Nalvi Duro
Microbial Community Structures in Three Bahamian Blue Holes, Meghan J. Gordon
A Novel Intramolecular Interaction in P53, Fan He
The Impact of Myeloid-Mediated Co-Stimulation and Immunosuppression on the Anti-Tumor Efficacy of Adoptive T cell Therapy, Pasquale Patrick Innamarato
Investigating Mechanisms of Immune Suppression Secondary to an Inflammatory Microenvironment, Wendy Michelle Kandell
Mechanistic and Translational Studies on Skeletal Malignancies, Jeremy McGuire
Novel Long Non-Coding RNA CDLINC Promotes NSCLC Progression, Christina J. Moss
Genome Maintenance Roles of Polycomb Transcriptional Repressors BMI1 and RNF2, Anthony Richard Sanchez IV
The Ecology and Conservation of an Urban Karst Subterranean Estuary, Robert J. Scharping
Biological and Proteomic Characterization of Cornus officinalis on Human 1.1B4 Pancreatic β Cells: Exploring Use for T1D Interventional Application, Arielle E. Tawfik
Evaluation of Aging and Genetic Mutation Variants on Tauopathy, Amber M. Tetlow
Theses/Dissertations from 2019
Investigating the Proteinaceous Regulome of the Acinetobacter baumannii, Leila G. Casella
Functional Characterization of the Ovarian Tumor Domain Deubiquitinating Enzyme 6B, Jasmin M. D'Andrea
Integrated Molecular Characterization of Lung Adenocarcinoma with Implications for Immunotherapy, Nicholas T. Gimbrone
The Role of Secreted Proteases in Regulating Disease Progression in Staphylococcus aureus, Brittney D. Gimza
Advanced Proteomic and Epigenetic Characterization of Ethanol-Induced Microglial Activation, Jennifer Guergues Guergues
Understanding immunometabolic and suppressive factors that impact cancer development, Rebecca Swearingen Hesterberg
Biochemical and Proteomic Approaches to Determine the Impact Level of Each Step of the Supply Chain on Tomato Fruit Quality, Robert T. Madden
Enhancing Immunotherapeutic Interventions for Treatment of Chronic Lymphocytic Leukemia, Kamira K. Maharaj
Characterization of the Autophagic-Iron Axis in the Pathophysiology of Endometriosis and Epithelial Ovarian Cancers, Stephanie Rockfield
Understanding the Influence of the Cancer Microenvironment on Metabolism and Metastasis, Shonagh Russell
Modeling of Interaction of Ions with Ether- and Ester-linked Phospholipids, Matthew W. Saunders
Novel Insights into the Multifaceted Roles of BLM in the Maintenance of Genome Stability, Vivek M. Shastri
Conserved glycine residues control transient helicity and disorder in the cold regulated protein, Cor15a, Oluwakemi Sowemimo
A Novel Cytokine Response Modulatory Function of MEK Inhibitors Mediates Therapeutic Efficacy, Mengyu Xie
Novel Strategies on Characterizing Biologically Specific Protein-protein Interaction Networks, Bi Zhao
Theses/Dissertations from 2018
Characterization of the Transcriptional Elongation Factor ELL3 in B cells and Its Role in B-cell Lymphoma Proliferation and Survival, Lou-Ella M.m. Alexander
Molecular Phylogenetics of Floridian Boletes, Arian Farid
MYC Distant Enhancers Underlie Ovarian Cancer Susceptibility at the 8q24.21 Locus, Anxhela Gjyshi Gustafson
Quantitative Proteomics to Support Translational Cancer Research, Melissa Hoffman
A Systems Chemical Biology Approach for Dissecting Differential Molecular Mechanisms of Action of Clinical Kinase Inhibitors in Lung Cancer, Natalia Junqueira Sumi
Investigating the Roles of Fucosylation and Calcium Signaling in Melanoma Invasion, Tyler S. Keeley
Synthesis, Oxidation, and Distribution of Polyphenols in Strawberry Fruit During Cold Storage, Katrina E. Kelly
Investigation of Alcohol-Induced Changes in Hepatic Histone Modifications Using Mass Spectrometry Based Proteomics, Crystina Leah Kriss
Off-Target Based Drug Repurposing Using Systems Pharmacology, Brent M. Kuenzi
Investigation of Anemarrhena asphodeloides and its Constituent Timosaponin-AIII as Novel, Naturally Derived Adjunctive Therapeutics for the Treatment of Advanced Pancreatic Cancer, Catherine B. MarElia
The Role of Phosphohistidine Phosphatase 1 in Ethanol-induced Liver Injury, Daniel Richard Martin
Theses/Dissertations from 2017
Changing the Pathobiological Paradigm in Myelodysplastic Syndromes: The NLRP3 Inflammasome Drives the MDS Phenotype, Ashley Basiorka
Modeling of Dynamic Allostery in Proteins Enabled by Machine Learning, Mohsen Botlani-Esfahani
Uncovering Transcriptional Activators and Targets of HSF-1 in Caenorhabditis elegans, Jessica Brunquell
The Role of Sgs1 and Exo1 in the Maintenance of Genome Stability., Lillian Campos-Doerfler
Mechanisms of IKBKE Activation in Cancer, Sridevi Challa
Discovering Antibacterial and Anti-Resistance Agents Targeting Multi-Drug Resistant ESKAPE Pathogens, Renee Fleeman
Functional Roles of Matrix Metalloproteinases in Bone Metastatic Prostate Cancer, Jeremy S. Frieling
Disorder Levels of c-Myb Transactivation Domain Regulate its Binding Affinity to the KIX Domain of CREB Binding Protein, Anusha Poosapati
Role of Heat Shock Transcription Factor 1 in Ovarian Cancer Epithelial-Mesenchymal Transition and Drug Sensitivity, Chase David Powell
Cell Division Regulation in Staphylococcus aureus, Catherine M. Spanoudis
A Novel Approach to the Discovery of Natural Products From Actinobacteria, Rahmy Tawfik
Non-classical regulators in Staphylococcus aureus, Andy Weiss
Theses/Dissertations from 2016
In Vitro and In Vivo Antioxidant Capacity of Synthetic and Natural Polyphenolic Compounds Identified from Strawberry and Fruit Juices, Marvin Abountiolas
Quantitative Proteomic Investigation of Disease Models of Type 2 Diabetes, Mark Gabriel Athanason
CMG Helicase Assembly and Activation: Regulation by c-Myc through Chromatin Decondensation and Novel Therapeutic Avenues for Cancer Treatment, Victoria Bryant
Computational Modeling of Allosteric Stimulation of Nipah Virus Host Binding Protein, Priyanka Dutta
Cell Cycle Arrest by TGFß1 is Dependent on the Inhibition of CMG Helicase Assembly and Activation, Brook Samuel Nepon-Sixt
Gene Expression Profiling and the Role of HSF1 in Ovarian Cancer in 3D Spheroid Models, Trillitye Paullin
VDR-RIPK1 Interaction and its Implications in Cell Death and Cancer Intervention, Waise Quarni
Regulation of nAChRs and Stemness by Nicotine and E-cigarettes in NSCLC, Courtney Schaal
Targeting Histone Deacetylases in Melanoma and T-cells to Improve Cancer Immunotherapy, Andressa Sodre De Castro Laino
Nonreplicative DNA Helicases Involved in Maintaining Genome Stability, Salahuddin Syed
Theses/Dissertations from 2015
Functional Analysis of the Ovarian Cancer Susceptibility Locus at 9p22.2 Reveals a Transcription Regulatory Network Mediated by BNC2 in Ovarian Cells, Melissa Buckley
Exploring the Pathogenic and Drug Resistance Mechanisms of Staphylococcus aureus, Whittney Burda
Regulation and Targeting of the FANCD2 Activation in DNA Repair, Valentina Celeste Caceres
Mass Spectrometry-Based Investigation of APP-Dependent Mechanisms in Neurodegeneration, Dale Chaput