Theses/Dissertations from 2016
In Vitro and In Vivo Antioxidant Capacity of Synthetic and Natural Polyphenolic Compounds Identified from Strawberry and Fruit Juices, Marvin Abountiolas
Quantitative Proteomic Investigation of Disease Models of Type 2 Diabetes, Mark Gabriel Athanason
CMG Helicase Assembly and Activation: Regulation by c-Myc through Chromatin Decondensation and Novel Therapeutic Avenues for Cancer Treatment, Victoria Bryant
Computational Modeling of Allosteric Stimulation of Nipah Virus Host Binding Protein, Priyanka Dutta
Cell Cycle Arrest by TGFß1 is Dependent on the Inhibition of CMG Helicase Assembly and Activation, Brook Samuel Nepon-Sixt
Gene Expression Profiling and the Role of HSF1 in Ovarian Cancer in 3D Spheroid Models, Trillitye Paullin
VDR-RIPK1 Interaction and its Implications in Cell Death and Cancer Intervention, Waise Quarni
Regulation of nAChRs and Stemness by Nicotine and E-cigarettes in NSCLC, Courtney Schaal
Targeting Histone Deacetylases in Melanoma and T-cells to Improve Cancer Immunotherapy, Andressa Sodre De Castro Laino
Nonreplicative DNA Helicases Involved in Maintaining Genome Stability, Salahuddin Syed
Theses/Dissertations from 2015
Functional Analysis of the Ovarian Cancer Susceptibility Locus at 9p22.2 Reveals a Transcription Regulatory Network Mediated by BNC2 in Ovarian Cells, Melissa Buckley
Exploring the Pathogenic and Drug Resistance Mechanisms of Staphylococcus aureus, Whittney Burda
Regulation and Targeting of the FANCD2 Activation in DNA Repair, Valentina Celeste Caceres
Mass Spectrometry-Based Investigation of APP-Dependent Mechanisms in Neurodegeneration, Dale Chaput
High-throughput Screening of Age-related Changes in Caenorhabditis elegans, Neil Copes
Promoting Genome Stability via Multiple DNA Repair Pathways, Scott Cukras
Strategies for Preventing Age and Neurodegenerative Disease-associated Mitochondrial Dysfunction, Vedad Delic
Genomic Aberrations at the 3q and 14q loci: Investigation of Key Players in Ovarian and Renal Cancer Biology, Punashi Dutta
The effects of supplemented metabolites on lifespan and stress response pathways in Caenorhabditis elegans, Clare B. Edwards
The Role of BRCT-Containing Proteins BRCA1 and PAXIP1 in Cancer, Ankita Jhuraney
Structure-Function Analysis of the DNA Damage Repair Complex STR in Saccharomyces cerevisiae, Jessica Ashley Kennedy
Investigation of Post-Translational Modifications in Staphylococcus aureus, Christina Nadia Krute
Characterization and Diurnal Measurement of Oral Inflammation in Association with Glycemic Control, Periodontal Status, & Glucose Stimulation, Melanie N. Kuehl
Exploring the Role of Intracellular Aminopeptidases in Staphylococcus aureus Pathogenesis, Devon Nicole Marking
Utilizing Systems Level Approaches to Identify Key Mechanisms of Drug Resistance in BRAF Mutated Melanoma, Kim H.T. Paraiso
Hepatic Nutrient and Hormonal Regulation of the PANcreatic-DERived Factor (PANDER) Promoter, Whitney Ratliff
Function of Long Noncoding RNAs in Breast Cancer, Edward J. Richards
In Situ Studies of Limestone Dissolution in a Coastal Submarine Spring, Rachel Marie Schweers
Theses/Dissertations from 2014
Manipulating the Tumor Microenvironment for Therapeutic Benefit, Kate M. Bailey
Characterization of Iron Response in Gynecological Cell Lines, Kyle A. Bauckman
Quantitative Proteomic Methodology Use and Development to Characterize Ethanol Modulation of Microglial Function, Harris Benjamin Bell-Temin
Mechanisms and Molecular Biology of Major Tumor Suppressors, Brienne E. Engel
Bi-directional signaling between melanoma and the microenvironment generates a protective niche that mediates therapeutic escape, Inna Fedorenko
Ube3a Role in Synaptic Plasticity and Neurodevelopmental Disorders.The Lessons from Angelman Syndrome., Irina Filonova
Investigating the Diversity of Single-Stranded DNA Bacteriophages in Marine Environments, Max Stephen Hopkins
Role and Regulation of SnoN/SkiL and PLSCR1 Located at 3q26.2 and 3q23, Respectively, in Ovarian Cancer Pathophysiology, Madhav Karthik Kodigepalli
Novel Therapeutic Strategies in Lung Cancer, Courtney A. Kurtyka
Karst Estuaries: A newly described ecosystem governed by aquifer hydrology, Damian M. Menning
Sigma Factor N: A Novel Regulator of Acid Resistance and Locus of Enterocyte Effacement in Escherichia coli O157:H7, Avishek Mitra
Genetic basis for the virulence of enterohemorrhagic Escherichia coli strain TW14359, Jason Kyle Morgan
Cancer and Infection, Kathleen Hope Plummer
Potential Targeted Therapeutic Strategies for Overcoming Resistance in BRAF Wild Type Melanoma, Vito William Rebecca
A Functional Approach to Resolving the Biogeocomplexity of Two Extreme Environments, Haydn Rubelmann III
Novel Roles of the Protein Tyrosine Phosphatase SHP2 in Non-small Cell Lung Cancer, Valentina Schneeberger
A Novel Role for NF-κB in Proximal T Cell Signaling, Crystina Bronk Watson
Theses/Dissertations from 2013
Structural Basis for Ternary Complex Formation Between tau, Hsp90, and FKBP51, Alexander Steven Barrett
Structure, Dynamics, and Evolution of the Intrinsically Disordered p53 Transactivation Domain, Wade Michael Borcherds
Epigenetic Modifiers to Augment the Immunogenicity of Chronic Lymphocytic Leukemia, Jason A. Dubovsky
The Mevalonate Pathway: A Potential Therapeutic Target for JAK2-driven Myeloproliferative Neoplasms, Lori Nicole Griner
Interrogation of EpoR Fidelity in Myelodysplastic Syndrome Hematopoiesis and Stabilization by the Immunomodulatory Agent, Lenalidomide, Kathy Lynn Mcgraw
Investigation of Hsf1 Interacting Partners via a Genome-wide Yeast Two-hybrid Screen, Jamie Elizabeth Mendez
Functional and mutational analysis of human RecQ-Like DNA helicases in Saccharomyces cerevisiae, Hamed Mirzaei-Souderjani
SIRT1 Regulation of the Heat Shock Response in an HSF1-Dependent Manner and the Impact of Caloric Restriction, Rachel Rene Raynes
Mass Spectrometry-based Methods for the Detection and Characterization of Protein-Tyrosine Nitration, Kent W. Seeley
Drug Resistance Mechanisms to Gamma-secretase Inhibitors in Human Colon Cancer Cells, Cindy R. Timme
Theses/Dissertations from 2012
The Role of Tumor Suppressors, SHIP and Rb, in Immune Suppressive Cells, Michelle Marie Collazo Ruiz
Targeting α4 Integrin Containing Complexes in Multiple Myeloma Using Peptidomimetics, Michael Foster Emmons
Sigma factor N (σN): A Novel Regulator of Extreme Acid Resistance in Enterohemorrhagic E. coli O157:H7, Pamela Ann Fay
Regulation of Natural Killer Cells: SHIP-1, 2B4, and Immunomodulation by Lenalidomide, Nicole Renee Fortenbery
Systematics of Harrisia (Cactaceae), Alan R. Franck
Investigation into the Mechanism of Salicylate-Associated Genotypic Antibiotic Resistance in Staphylococcus aureus, Nada Salah Helal
Enhancing the immune response through IKKbeta-induced activation of NF-kappaB, Emily Hopewell
Matrix Metalloproteinase genes are transcriptionally regulated by E2F transcription factors: a link between cell cycle control and metastatic progression, Jacqueline Lea Johnson
The Role and Regulation of NsaRS: a Cell-Envelope Stress Sensing Two-Component System in Staphylococcus aureus, Stacey Lynn Kolar
Lenalidomide targets the T-cell co-stimulatory pathway to mediate immune modulation, Jessica Marie Mcdaniel
Characterization of the Lone Extracytoplasmic Function Sigma Factor, óS, and its Role in the Staphylococcus aureus Virulence and Stress Responses, Halie Kay Miller
Structure and Dynamics of the p53 Transactivation Domain Binding to MDM2 and RPA70, Anne Terese Powell
Comparative Developmental Transcriptomics of Echinoderms, Roy Vaughn
Theses/Dissertations from 2011
Inhibition of p53 DNA binding function by the MDM2 acidic domain, Brittany Lynne Cross
Analysis of Ahr Expression and Stability in a Recombinant Yeast Model System, Sarah Elizabeth Cuccinello
From DNA to Protein: a study of genomic instability candidate genes during zebrafish development, Kristine Griffett
Identification of Novel STAT3 Target Genes Associated with Oncogenesis, Rachel Haviland
Characterization of Aminopeptidase PepZ in Staphylococcus aureus Virulence, Tiffany Marie Robison
The Role of BRCA1 Domains and Motifs in Tumor Suppression, Aneliya Velkova
Theses/Dissertations from 2010
Regulation of Positive Regulatory Domain I- Binding Factor 1 and Its Role in Mantle Cell Lymphoma, Shruti Desai
The Biogeochemistry of Submerged Coastal Karst Features in West Central Florida, Keith Michael Garman
A Comparative Study of the Plants Used for Medicinal Purposes by the Creek and Seminoles Tribes, Kimberly Hutton
A Potential Tumor Suppressive Role of SIRT1 in Cancer, Neha Kabra
The Biocomplexity of Benthic Communities Associated with a Shallow-water Hydrothermal System in Papua New Guinea, David J. Karlen
Investigating the Mode of Action of a Novel N-sec-butylthiolated Beta-lactam Against Staphylococcus aureus, Katherine Rose Prosen
The Use of Proteomic Techniques to Study the Physiology and Virulence of Staphylococcus aureus, Frances Rivera
Chromatin Unfolding by Cdt1 Regulates MCM Loading via Opposing Functions of HBO1 and HDAC11-Geminin, Philip G. Wong
The Fanconi Anemia (FA)/BRCA DNA Damage Repair Pathway is Regulated by NF-κB and Mediates Drug Resistance in Multiple Myeloma, Danielle N. Yarde
Theses/Dissertations from 2009
Novel Roles for B-Raf in Mitosis and Cancer, Meghan E. K Borysova
Inositol Phospholipid and Tyrosine Phosphorylation Signaling in the Biology of Hematopoietic Stem Cells, Amy L. Hazen
Statistical and Data Mining Methodologies for Behavioral Analysis in Transgenic Mouse Models of Alzheimer’s Disease: Parallels with Human AD Evaluation, Ralph E. Leighty
A novel antibody based capture matrix utilizing human serum albumin and streptococcal Protein G to increase capture efficiency of bacteria, Christie Renee McCabe
The Rad9-Rad1-Hus1 complex and Bif-1 regulate multiple mechanisms that affect sensitivity to DNA damage, Cheryl L. Meyerkord
Theses/Dissertations from 2008
Tumor Suppressive Effects of the Beta-2 Adrenergic Receptor and the Small GTPase RhoB, Adam E. Carie
The Role of RalA and RalB in Cancer, Samuel C. Falsetti
Multiple Modes of Mdmx Regulation Affect p53 Activation, Daniele M. Gilkes
Rb-Raf-1 Interaction as a Therapeutic Target for Proliferative Disorders, Rebecca Kinkade
Regulation of Bax Activation and Apoptosis by Src and Acetylated Mutant p53, Nicholas Taylor Woods
Theses/Dissertations from 2007
Analysis of E2F1 target genes involved in cell cycle and apoptosis, Scott N. Freeman
Regulation of MDMX nuclear import and degradation by Chk2 and 14-3-3, Cynthia LeBron
Bcl-2 related ovarian killer, Bok, is cell cycle regulated and sensitizes to stress-induced apoptosis, José M. Rodríguez