Theses/Dissertations from 2024
Black Holes in TIME: the Effect of GRID Radiation on the Tumor Immune Microenvironment, Rebecca A. Bekker
The Role of L-fucose in Dendritic Cell Antigen Presentation and Polarization, Chase J. Burton
Cornus officinalis extract activates the Keap1/Nrf2 pathway and delays T1D onset in the NOD mouse, Justin D. Fletcher
Androgen Drives Melanoma Invasiveness and Metastatic Spread by Inducing Tumorigenic Fucosylation, Qian Liu
TetR Family Regulator, FarR, Influences Rot-mediated Control of Virulence Factor Expression in Staphylococcus aureus, Julia C. Schumacher
Theses/Dissertations from 2023
Exploring strain variation and bacteriophage predation in the gut microbiome of Ciona robusta, Celine Grace F. Atkinson
Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression, Janine M. DeBlasi
Thermodynamic frustration of TAD2 and PRR contribute to autoinhibition of p53, Emily Gregory
Utilization of Detonation Nanodiamonds: Nanocarrier for Gene Therapy in Non-Small Cell Lung Cancer, Allan E. Gutierrez
Utilizing neoantigen-specific CD4* T cells and immune checkpoint modulation to advance adoptive cell therapy with tumor-infiltrating lymphocytes for metastatic melanoma patients, Maclean Scott Hall
Role of HLA-DRB1 Fucosylation in Anti-Melanoma Immunity, Daniel K. Lester
Targeting BET Proteins Downregulates miR-33a To Promote Synergy with PIM Inhibitors in CMML, Christopher T. Letson
The Role of the DNA Helicase Rrm3 under Replication Stress, Julius Muellner
Regulated Intramembrane Proteolysis by M82 Peptidases: The Role of PrsS in the Staphylococcus aureus Stress Response, Baylie M. Schott
Histone Deacetylase 8 is a Novel Therapeutic Target for Mantle Cell Lymphoma and Preserves Natural Killer Cell Cytotoxic Function, January M. Watters
Theses/Dissertations from 2022
Ceramide-1-Phosphate: A Novel Regulator of Golgi Fragmentation, Golgi-ER Vesicle Trafficking, and Anaplasma phagocytophilum Pathogenesis, Anika Nayar Ali
Regulation of the Heat Shock Response via Lysine Acetyltransferase CBP-1 and in Neurodegenerative Disease in Caenorhabditis elegans, Lindsey N. Barrett
Establishment of a Melanoma ESC-GEMM Platform and Its Use to Study PTEN Tumor Suppressor Functions, Ilah Bok
Adrenergic Modulation of Precursor Cells of Ovarian Cancer, Sweta Dash
Determining the Role of Dendritic Cells During Response to Treatment with Paclitaxel/Anti-TIM-3, Alycia Gardner
To be or not to be: A Tale of Staphylococcal GpsB, Lauren R. Hammond
Origin and Epigenetic Regulation of Cutaneous T Cell Lymphoma, Carly M. Harro
Cell-free DNA Methylation Signatures in Cancer Detection and Classification, Jinyong Huang
The Role Of Eicosanoid Metabolism in Mammalian Wound Healing and Inflammation, Kenneth D. Maus
A Holistic Investigation of Acidosis in Breast Cancer, Bryce Ordway
Characterizing the Impact of Postharvest Temperature Stress on Polyphenol Profiles of Red and White-Fruited Strawberry Cultivars, Alyssa N. Smith
Identification of Secondary Structural Elements Contained Within the Intrinsically Disordered N-Terminal Tail of the Bloom’s Syndrome Helicase., Vivek Somasundaram
Defining the role of Oxidized Mitochondrial DNA in Myelodysplastic Syndromes, Grace Anne Ward
Lord of the Z-rings: Uncovering the Role of MraZ and FtsL in Bacillus subtilis Cell Division, Maria Louise White
Theses/Dissertations from 2021
Multifaceted Approach to Understanding Acinetobacter baumannii Biofilm Formation and Drug Resistance, Jessie L. Allen
Cellular And Molecular Alterations Associated with Ovarian and Renal Cancer Pathophysiology, Ravneet Kaur Chhabra
Ecology and diversity of boletes of the southeastern United States, Arian Farid
CircREV1 Expression in Triple-Negative Breast Cancer, Meagan P. Horton
Microbial Dark Matter: Culturing the Uncultured in Search of Novel Chemotaxonomy, Sarah J. Kennedy
The Multifaceted Role of CCAR-1 in the Alternative Splicing and Germline Regulation in Caenorhabditis elegans, Doreen Ikhuva Lugano
Unraveling the Role of Novel G5 Peptidase Family Proteins in Virulence and Cell Envelope Biogenesis of Staphylococcus aureus, Stephanie M. Marroquin
Cytoplasmic Polyadenylation Element Binding Protein 2 Alternative Splicing Regulates HIF1α During Chronic Hypoxia, Emily M. Mayo
Transcriptomic and Functional Investigation of Bacterial Biofilm Formation, Brooke R. Nemec
A Functional Characterization of the Omega (ω) subunit of RNA Polymerase in Staphylococcus aureus, Shrushti B. Patil
The Role Of Cpeb2 Alternative Splicing In TNBC Metastasis, Shaun C. Stevens
Theses/Dissertations from 2020
Understanding the Role of Cereblon in Hematopoiesis Through Structural and Functional Analyses, Afua Adutwumwa Akuffo
To Mid-cell and Beyond: Characterizing the Roles of GpsB and YpsA in Cell Division Regulation in Gram-positive Bacteria, Robert S. Brzozowski
Spatiotemporal Changes of Microbial Community Assemblages and Functions in the Subsurface, Madison C. Davis
New Mechanisms That Regulate DNA Double-Strand Break-Induced Gene Silencing and Genome Integrity, Dante Francis DeAscanis
Regulation of the Heat Shock Response and HSF-1 Nuclear Stress Bodies in C. elegans, Andrew Deonarine
New Mechanisms that Control FACT Histone Chaperone and Transcription-mediated Genome Stability, Angelo Vincenzo de Vivo Diaz
Targeting the ESKAPE Pathogens by Botanical and Microbial Approaches, Emily Dilandro
Succession in native groundwater microbial communities in response to effluent wastewater, Chelsea M. Dinon
Role of ceramide-1 phosphate in regulation of sphingolipid and eicosanoid metabolism in lung epithelial cells, Brittany A. Dudley
Allosteric Control of Proteins: New Methods and Mechanisms, Nalvi Duro
Microbial Community Structures in Three Bahamian Blue Holes, Meghan J. Gordon
A Novel Intramolecular Interaction in P53, Fan He
The Impact of Myeloid-Mediated Co-Stimulation and Immunosuppression on the Anti-Tumor Efficacy of Adoptive T cell Therapy, Pasquale Patrick Innamarato
Investigating Mechanisms of Immune Suppression Secondary to an Inflammatory Microenvironment, Wendy Michelle Kandell
Mechanistic and Translational Studies on Skeletal Malignancies, Jeremy McGuire
Novel Long Non-Coding RNA CDLINC Promotes NSCLC Progression, Christina J. Moss
Genome Maintenance Roles of Polycomb Transcriptional Repressors BMI1 and RNF2, Anthony Richard Sanchez IV
The Ecology and Conservation of an Urban Karst Subterranean Estuary, Robert J. Scharping
Biological and Proteomic Characterization of Cornus officinalis on Human 1.1B4 Pancreatic β Cells: Exploring Use for T1D Interventional Application, Arielle E. Tawfik
Evaluation of Aging and Genetic Mutation Variants on Tauopathy, Amber M. Tetlow
Theses/Dissertations from 2019
Investigating the Proteinaceous Regulome of the Acinetobacter baumannii, Leila G. Casella
Functional Characterization of the Ovarian Tumor Domain Deubiquitinating Enzyme 6B, Jasmin M. D'Andrea
Integrated Molecular Characterization of Lung Adenocarcinoma with Implications for Immunotherapy, Nicholas T. Gimbrone
The Role of Secreted Proteases in Regulating Disease Progression in Staphylococcus aureus, Brittney D. Gimza
Advanced Proteomic and Epigenetic Characterization of Ethanol-Induced Microglial Activation, Jennifer Guergues Guergues
Understanding immunometabolic and suppressive factors that impact cancer development, Rebecca Swearingen Hesterberg
Biochemical and Proteomic Approaches to Determine the Impact Level of Each Step of the Supply Chain on Tomato Fruit Quality, Robert T. Madden
Enhancing Immunotherapeutic Interventions for Treatment of Chronic Lymphocytic Leukemia, Kamira K. Maharaj
Characterization of the Autophagic-Iron Axis in the Pathophysiology of Endometriosis and Epithelial Ovarian Cancers, Stephanie Rockfield
Understanding the Influence of the Cancer Microenvironment on Metabolism and Metastasis, Shonagh Russell
Modeling of Interaction of Ions with Ether- and Ester-linked Phospholipids, Matthew W. Saunders
Novel Insights into the Multifaceted Roles of BLM in the Maintenance of Genome Stability, Vivek M. Shastri
Conserved glycine residues control transient helicity and disorder in the cold regulated protein, Cor15a, Oluwakemi Sowemimo
A Novel Cytokine Response Modulatory Function of MEK Inhibitors Mediates Therapeutic Efficacy, Mengyu Xie
Novel Strategies on Characterizing Biologically Specific Protein-protein Interaction Networks, Bi Zhao
Theses/Dissertations from 2018
Characterization of the Transcriptional Elongation Factor ELL3 in B cells and Its Role in B-cell Lymphoma Proliferation and Survival, Lou-Ella M.m. Alexander
Molecular Phylogenetics of Floridian Boletes, Arian Farid
MYC Distant Enhancers Underlie Ovarian Cancer Susceptibility at the 8q24.21 Locus, Anxhela Gjyshi Gustafson
Quantitative Proteomics to Support Translational Cancer Research, Melissa Hoffman
A Systems Chemical Biology Approach for Dissecting Differential Molecular Mechanisms of Action of Clinical Kinase Inhibitors in Lung Cancer, Natalia Junqueira Sumi
Investigating the Roles of Fucosylation and Calcium Signaling in Melanoma Invasion, Tyler S. Keeley
Synthesis, Oxidation, and Distribution of Polyphenols in Strawberry Fruit During Cold Storage, Katrina E. Kelly
Investigation of Alcohol-Induced Changes in Hepatic Histone Modifications Using Mass Spectrometry Based Proteomics, Crystina Leah Kriss
Off-Target Based Drug Repurposing Using Systems Pharmacology, Brent M. Kuenzi
Investigation of Anemarrhena asphodeloides and its Constituent Timosaponin-AIII as Novel, Naturally Derived Adjunctive Therapeutics for the Treatment of Advanced Pancreatic Cancer, Catherine B. MarElia
The Role of Phosphohistidine Phosphatase 1 in Ethanol-induced Liver Injury, Daniel Richard Martin
Theses/Dissertations from 2017
Changing the Pathobiological Paradigm in Myelodysplastic Syndromes: The NLRP3 Inflammasome Drives the MDS Phenotype, Ashley Basiorka
Modeling of Dynamic Allostery in Proteins Enabled by Machine Learning, Mohsen Botlani-Esfahani
Uncovering Transcriptional Activators and Targets of HSF-1 in Caenorhabditis elegans, Jessica Brunquell
The Role of Sgs1 and Exo1 in the Maintenance of Genome Stability., Lillian Campos-Doerfler
Mechanisms of IKBKE Activation in Cancer, Sridevi Challa
Discovering Antibacterial and Anti-Resistance Agents Targeting Multi-Drug Resistant ESKAPE Pathogens, Renee Fleeman
Functional Roles of Matrix Metalloproteinases in Bone Metastatic Prostate Cancer, Jeremy S. Frieling
Disorder Levels of c-Myb Transactivation Domain Regulate its Binding Affinity to the KIX Domain of CREB Binding Protein, Anusha Poosapati
Role of Heat Shock Transcription Factor 1 in Ovarian Cancer Epithelial-Mesenchymal Transition and Drug Sensitivity, Chase David Powell
Cell Division Regulation in Staphylococcus aureus, Catherine M. Spanoudis
A Novel Approach to the Discovery of Natural Products From Actinobacteria, Rahmy Tawfik
