On the Potential Role of Exosomes in the COVID-19 Reinfection/reactivation Opportunity

Document Type

Article

Publication Date

2021

Keywords

Sars-cov-2, COVID-19, Reinfection, Exosome, Extracellular Vesicle

Digital Object Identifier (DOI)

https://doi.org/10.1080/07391102.2020.1790426

Abstract

We propose here that one of the potential mechanisms for the relapse of the COVID-19 infection could be a cellular transport pathway associated with the release of the SARS-CoV-2-loaded exosomes and other extracellular vesicles. It is possible that this “Trojan horse” strategy represents possible explanation for the re-appearance of the viral RNA in the recovered COVID-19 patients 7–14 day post discharge, suggesting that viral material was hidden within such exosomes or extracellular vesicles during this “silence” time period and then started to re-spread again.

Was this content written or created while at USF?

Yes

Citation / Publisher Attribution

Journal of Biomolecular Structure and Dynamics, v. 39, issue 15, p. 58361-5842

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