On the Potential of Using Peculiarities of the Protein Intrinsic Disorder Distribution in Mitochondrial Cytochrome B to Identify the Source of Animal Meats
Document Type
Article
Publication Date
2017
Keywords
adulteration, animal species, authentication, avian species, food products, intrinsically disordered protein, intrinsically disordered region, meat, mitochondrial cytochrome b
Digital Object Identifier (DOI)
https://doi.org/10.1080/21690707.2016.1264350
Abstract
This study was conducted to identify the source of animal meat based on the peculiarities of protein intrinsic disorder distribution in mitochondrial cytochrome b (mtCyt-b). The analysis revealed that animal and avian species can be discriminated based on the proportions of the two groups of residues, Leu+Ile, and Ser+Pro+Ala, in the amino acid sequences of their mtCyt-b. Although levels of the overall intrinsic disorder in mtCyt-b is not very high, the peculiarities of disorder distribution within the sequences of mtCyt-b from different species varies in a rather specific way. In fact, positions and intensities of disorder/flexibility “signals” in the corresponding disorder profiles are relatively unique for avian and animal species. Therefore, it is possible to devise a set of simple rules based on the peculiarities of disorder profiles of their mtCyt-b proteins to discriminate among species. This intrinsic disorder-based analysis represents a new technique that could be used to provide a promising solution for identification of the source of meats.
Was this content written or created while at USF?
Yes
Citation / Publisher Attribution
Intrinsically Disordered Proteins, v. 5, issue 5, art. e1264350
Scholar Commons Citation
Yacoub, Haitham A.; Sadek, Mahmoud A.; and Uversky, Vladimir N., "On the Potential of Using Peculiarities of the Protein Intrinsic Disorder Distribution in Mitochondrial Cytochrome B to Identify the Source of Animal Meats" (2017). Molecular Medicine Faculty Publications. 37.
https://digitalcommons.usf.edu/mme_facpub/37
