Document Type

Patent

Publication Date

1-24-2017

Patent Number

9550992

CPC

C12N 15/113 (20130101)

Abstract

Provided are methods and compositions for modulating the differentiation of a myeloid derived suppressor cell (MDSC). In particular, described herein are miR-142 polynucleotides and miR-223 polynucleotides that can be used to modulate differentiation of MDSCs. Increased differentiation of a MDSC population, or cells within an MDSC population, can be achieved by increasing the miR-142 and/or miR-223 polynucleotides in a MDSC.

Application Number

14/361,537

Assignees

University of South Florida

Filing Date

2013-06-06

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