Document Type
Patent
Publication Date
12-6-2016
Patent Number
9513286
CPC
G01N 33/564 (20130101)
Abstract
The subject invention concerns gene sequences and the use thereof as markers for large granular lymphocyte (LGL) leukemia. The gene sequences of the invention are differentially expressed in LGL. Another aspect of the invention pertains to therapeutic compositions directed to gene expression and gene products of differentially expressed genes in LGL. The invention also concerns methods for screening and identifying compositions that may be of therapeutic benefit to patients having LGL leukemia and/or autoimmune disorders. In addition, because a large fraction of patients with T-LGL leukemia also have rheumatoid arthritis, these differentially expressed genes also represent novel targets for the diagnosis, prevention or treatment of rheumatoid arthritis and other autoimmune diseases.
Application Number
11/476,407
Recommended Citation
Loughran, Thomas P. Jr. and Kothapalli, Ravi, "Differentially expressed genes in large granular lymphocyte leukemia" (2016). USF Patents. 910.
https://digitalcommons.usf.edu/usf_patents/910
Assignees
University of South Florida
Filing Date
2006-06-28
