Document Type
Patent
Publication Date
May 2000
Patent Number
60690062
Abstract
The present invention provides a novel polypeptide, Connective Tissue Growth Factor (CTGF), polynucleotides encoding CTGF, and including 5' and 3' untranslated nucleotides, antibodies reactive with CTGF and means for producing CTGF. Also provided are diagnostic and therapeutic methods for using CTGF, as well as an assay for identifying compositions which affect the expression of CTGF polynucleotide. The invention provides a novel TGF-.beta. responsive element upstream of the polynucleotide encoding CTGF structural gene.
Application Number
09/054,368
Recommended Citation
Grotendorst, Gary R. and Bradham, Douglass Douglass M., "Connective tissue growth factor (CTGF) regulatory nucleic acid sequences" (2000). USF Patents. 822.
https://digitalcommons.usf.edu/usf_patents/822
Assignees
University of South Florida
Filing Date
04/02/1998
Primary/U.S. Class
435/325
