Document Type
Patent
Publication Date
November 2000
Patent Number
61501018
Abstract
The present invention provides a novel polypeptide, Connective Tissue Growth Factor (CTGF), polynucleotides encoding CTGF, and including 5' and 3' untranslated nucleotides, antibodies reactive with CTGF and means for producing CTGF. Also provided are diagnostic and therapeutic methods for using CTGF, as well as an assay for identifying compositions which affect the expression of CTGF polynucleotide. The invention provides a novel TGF-.beta. responsive element upstream of the polynucleotide encoding CTGF structural gene.
Application Number
09/054,274
Recommended Citation
Grotendorst, Gary R. and Bradham, Douglass Douglass M., "Methods of identifying a composition that alters connective tissue growth factor expression" (2000). USF Patents. 816.
https://digitalcommons.usf.edu/usf_patents/816
Assignees
University of South Florida
Filing Date
04/02/1998
Primary/U.S. Class
435/6
