Document Type
Patent
Publication Date
May 2001
Patent Number
62320645
Abstract
The present invention provides a novel polypeptide, Connective Tissue Growth Factor (CTGF), polynucleotides encoding CTGF, and including 5' and 3' untranslated nucleotides, antibodies reactive with CTGF and means for producing CTGF. Also provided are diagnostic and therapeutic methods for using CTGF, as well as an assay for identifying compositions which affect the expression of CTGF polynucleotide. The invention provides a novel TGF-.beta. responsive element upstream of the polynucleotide encoding CTGF structural gene.
Application Number
09/056,704
Recommended Citation
Grotendorst, Gary R. and Bradham, Douglass Douglass M., "Methods of diagnosing a pathology characterized by a cell proliferative disorder associated with connective tissue growth factor" (2001). USF Patents. 807.
https://digitalcommons.usf.edu/usf_patents/807
Assignees
University of South Florida
Filing Date
03/30/1998
Primary/U.S. Class
435/6
