Document Type

Patent

Publication Date

February 2002

Patent Number

6344443

Abstract

There is provided a method of inhibiting TNF-α from binding to TNF receptors by administering an effective amount of an inhibitory peptide. Also provided is a method of inhibiting TNF-α functions by administering an effective amount of an inhibitory peptide. There also are provided peptides which have TNF-α inhibitory properties. Also provided is a method of inhibiting TNF-α binding to TNF receptors by administering an effective amount of peptides having the amino acid sequences shown in SEQ ID No. 1,2,3,4, wherein the peptides can be administered either singly or in combination.

Application Number

09/349,661

Assignees

University of South Florida

Filing Date

07/08/1999

Primary/U.S. Class

514/14

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