Document Type
Patent
Publication Date
March 2004
Patent Number
6706756
Abstract
The present invention is an isolated compound and method of inducing endothelium-dependent relaxation in blood vessels including the step of introducing isolated procyanidins having a preponderance of (−)-epicatechins to a patient wherein the procyanidins are preferably galloylated. To achieve both bioavailability and potency, it is also preferred that the number of epicatechins monomers forming each procyanidin is between two and five. More specifically, isolated epicatechin-(4-8)-epicatechin-(4-8)-epicatechin-gallate (C1-gallate) is administered to the patient.
Application Number
10/065,770
Recommended Citation
Fitzpatrick, David F., "Vasodilating compound and method of use" (2004). USF Patents. 748.
https://digitalcommons.usf.edu/usf_patents/748
Assignees
University of South Florida
Filing Date
11/18/2002
Primary/U.S. Class
514/456
