Document Type
Patent
Publication Date
February 2004
Patent Number
6689890
Abstract
Lactams, libraries of lactams, and an efficient method of synthesizing a lactam, including a γ-lactam, in which an α-diazoacetamide of the general structure (I) is reacted under conditions promoting intramolecular C—H insertion, for example in the presence of a rhodium salt such as Rhby which means lactams that are precursors in the synthesis of diverse natural and synthetic products, including pyrrolidinone compounds such as lactacystin, pramanicin, kainic acid, statine, AHPPA, and rolipram, are produced.
Application Number
10/323,537
Recommended Citation
Jung, Kyung Woon and Yoon, Cheol Hwan, "Efficient lactam synthesis" (2004). USF Patents. 744.
https://digitalcommons.usf.edu/usf_patents/744
Assignees
University of South Florida
Filing Date
12/18/2002
Primary/U.S. Class
548/544
