Document Type
Patent
Publication Date
May 2005
Patent Number
6900299
Abstract
There is provided a method of preventing a respiratory infection by administering an effective amount of an agent for regulating ICAM-1 expression. Also provided is a composition for the prevention of respiratory infection including an agent which regulates ICAM expression. method of preventing RSV infection by administering an effective amount of an agent that interferes with the binding of RSV to ICAM-1. A method of preventing RSV infection by administering an effective amount of an agent that down regulates the expression of ICAM-1, thereby decreasing RSV binding to ICAM-1 is also provided. There is provided a method of treating RSV infection by administering an effective amount of an agent for down regulating ICAM-1 expression. A method of blocking RSV-ICAM-1 interaction by administering an effective amount of agents for blocking ICAM sites of binding is provided. Also provided is a compound for blocking RSV-ICAM-1 interaction including an agent for blocking ICAM sites of binding.
Application Number
10/440,000
Recommended Citation
Mohapatra, Shyam S.; Behera, Aruna; Matsuse, Hiroto; and Kumar, Mukesh, "Interrupting the interaction of intercellular adhesion molecule-1 and respiratory syncytial virus for prevention and treatment of infection" (2005). USF Patents. 709.
https://digitalcommons.usf.edu/usf_patents/709
Assignees
University of South Florida
Filing Date
05/16/2003
Primary/U.S. Class
536/221
