Document Type
Patent
Publication Date
February 2006
Patent Number
6998040
Abstract
The present invention provides for a column for use in capillary electrochromatography including a tube, wherein the tube includes an inner surface having a positively or negatively charged, chemically-bonded stationary coating thereon. The present invention further provides for a method of making a column for use in capillary electrochromatography, including a tube, wherein the tube includes an inner surface having a positively or negatively charged chemically-bonded stationary coating thereon, wherein the steps include filling the column with a sol-gel solution, maintaining the sol-gel solution within the column, and forcing the sol-gel solution out of the column with an inert gas. Further, the present invention provides for a method of analytical separation with a column including an inner layer having a positively charged chemically-bonded stationary coating thereon that reverses the direction of electroosmotic flow in the column compared with a column without the positive surface charge. Additionally, the present invention provides for a method of using a column including an inner layer of positively charged chemically-bonded stationary coating thereon by introducing a sample into the column operating under reversed electroosmotic flow due to positively charged chemically-bonded stationary coating.
Application Number
10/057,080
Recommended Citation
Malik, Abdul and Hayes, James D., "Sol-gel open tubular ODS columns with charged inner surface for capillary electrochromatography" (2006). USF Patents. 646.
https://digitalcommons.usf.edu/usf_patents/646
Assignees
University of South Florida
Filing Date
01/24/2002
Primary/U.S. Class
210/198
