Document Type
Patent
Publication Date
October 2008
Patent Number
7442390
Abstract
The present invention provides isolated pluri-differentiated human mesenchymal progenitor cells (MPCs), which simultaneously express a plurality of genes that are markers for multiple cell lineages, wherein the multiple cell lineages comprise at least four different mesenchymal cell lineages (e.g., adipocyte, osteoblast, fibroblast, and muscle cell) and wherein each of the markers is specific for a single cell lineage. The present invention also method for isolating and purifying human mesenchymal progenitor cells from Dexter-type cultures for characterization of and uses, particularly therapeutic uses for such cells. Specifically, isolated MPCs can be used for diagnostic purposes, to enhance the engraftment of hematopoietic progenitor cells, enhance bone marrow transplantation, or aid in the treatment or prevention of graft versus host disease.
Application Number
10/887,582
Recommended Citation
Seshi, Beerelli, "Method for enhancing engraftment of cells using mesenchymal progenitor cells" (2008). USF Patents. 611.
https://digitalcommons.usf.edu/usf_patents/611
Assignees
University of South Florida
Filing Date
07/09/2004
Primary/U.S. Class
424/577
