Document Type
Patent
Publication Date
March 2008
Patent Number
7342095
Abstract
The subject invention concerns compositions and methods for blocking cancer cell growth or proliferation and/or inducing cancer cell death. Compositions of the present invention are peptidomimetics that inhibit STAT function. Peptidomimetics of the invention include compounds of the formula RY*L (where Y* represents phosphotyrosine), with the R group at the Y-1 position. Peptidomimetics of the invention disrupt Stat3 activation and function. Peptidomimetics of the invention significantly inhibit tumor cell growth and induce tumor cell death.
Application Number
10/784,309
Recommended Citation
Turkson, James; Jove, Richard; Sebti, Said M.; and Hamilton, Andrew D., "Peptidomimetic inhibitors of STAT activity and uses thereof" (2008). USF Patents. 590.
https://digitalcommons.usf.edu/usf_patents/590
Assignees
University of South Florida
Filing Date
02/20/2004
Primary/U.S. Class
530/331
