Document Type
Patent
Publication Date
January 2009
Patent Number
7482467
Abstract
This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class of anti bacterial agents. These compounds can be synthesized from 2-oxazolidinones by Ndeprotection and N-sulfenylation. These new substances were found to exhibit potent anti-bacterial activity, including bacteriostatic properties against Staphylococcus spp., including methicillin resistant Staphylococcus aureus (MRSA), and Bacillus spp., including Bacillus anthracis.
Application Number
11/948,073
Recommended Citation
Turos, Edward and Mishra, Rajesh Kumar, "N-thiolated 2-oxazolidinone-derived antibiotics" (2009). USF Patents. 546.
https://digitalcommons.usf.edu/usf_patents/546
Assignees
University of South Florida
Filing Date
11/30/2007
Primary/U.S. Class
548/230