Document Type

Patent

Publication Date

January 2009

Patent Number

7482467

Abstract

This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class of anti bacterial agents. These compounds can be synthesized from 2-oxazolidinones by Ndeprotection and N-sulfenylation. These new substances were found to exhibit potent anti-bacterial activity, including bacteriostatic properties against Staphylococcus spp., including methicillin resistant Staphylococcus aureus (MRSA), and Bacillus spp., including Bacillus anthracis.

Application Number

11/948,073

Assignees

University of South Florida

Filing Date

11/30/2007

Primary/U.S. Class

548/230

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