Document Type
Patent
Publication Date
November 2010
Patent Number
7842671
Abstract
The subject invention concerns compositions and methods for blocking cancer cell growth or proliferation and/or inducing cancer cell death. Compositions of the present invention are peptidomimetics that inhibit STAT function. Peptidomimetics of the invention include compounds of the formula RY*L (where Y* represents phosphotyrosine), with the R group at the Y-1 position. Peptidomimetics of the invention disrupt Stat3 activation and function. Peptidomimetics of the invention significantly inhibit tumor cell growth and induce tumor cell death.
Application Number
11/986,237
Recommended Citation
Turkson, James; Jove, Richard; Sebti, Said M.; and Hamilton, Andrew D., "Peptidomimetic inhibitors of STAT activity and uses thereof" (2010). USF Patents. 537.
https://digitalcommons.usf.edu/usf_patents/537
Assignees
University of South Florida
Filing Date
11/19/2007
Primary/U.S. Class
514/19
