Document Type
Patent
Publication Date
September 2010
Patent Number
7799191
Abstract
The present invention provides a polymer membrane enhanced with cured epoxy resin for use as the outer membrane of biosensors. The membrane includes approximately 30-80% epoxy resin adhesives, 10-60% polymer such as poly(vinyl chloride), polycarbonate and polyurethane and 0-30% plasticizers and 5-15% surface modifier reagent such as polyethylene oxide-containing block copolymers. Utilizing the polymer membrane of the present invention, a three-layered sensing element has been developed. This sensing element will be particularly useful for miniaturized biosensors used for in vitro blood measurements or for continuous in vivo monitoring such as implantable biosensors. This element includes an enzyme layer, an interference-eliminating layer and the novel polymer member of the present invention as the outer polymer layer. This novel sensing element shows excellent response characteristics in solutions and has an extremely long lifetime. This technology is particularly useful for improving the lifetime of implantable biosensors.
Application Number
12/015,614
Recommended Citation
Yu, Bazhang and Moussy, Francis, "Epoxy enhanced polymer membrane to increase durability of biosensors" (2010). USF Patents. 518.
https://digitalcommons.usf.edu/usf_patents/518
Assignees
University of South Florida
Filing Date
01/17/2008
Primary/U.S. Class
204/403
