Authors

Wei Chen

Document Type

Patent

Publication Date

December 2011

Patent Number

8073549

Abstract

Activation of electrogenic pump molecules can be realized by a dynamic entrainment procedure which includes two steps: synchronization of individual pump molecules to work at the same pumping pace, and gradual modulation of the synchronization frequency. Na/K pump molecules were used as an example in a physiological operating mode by applying the concept of an electronic synchrotron to the biological system. It was shown that individual Na/K pump molecules can be synchronized by a well designed oscillating electric field. The synchronized pump currents show separated inward and outward pump currents and a magnitude ratio of 3:2 reflecting stoichiometric number of the pump molecules.

Application Number

12/762,708

Assignees

University of South Florida

Filing Date

04/19/2010

Primary/U.S. Class

607/76

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