Document Type
Patent
Publication Date
December 2011
Patent Number
8071560
Abstract
This invention pertains to inhibitors of atrial natriuretic peptide receptor A (NPRA) function, such as small interfering RNA (siRNA), useful for reducing the inflammation associated with many human diseases, such as asthma, respiratory syncytial virus (RSV) infection, and cancers (such as melanoma, lung cancer, and/or ovarian cancer) by interfering with NPRA gene expression or otherwise reducing NPRA function within a subject; and methods for treating a subject suffering from, or at risk of developing, an inflammatory disease, respiratory allergy (such as allergic rhinitis and asthma), viral infection, and/or cancer by administering such NPRA inhibitors to the subject.
Application Number
11/799,225
Recommended Citation
Mohapatra, Shyam S.; Xu, Weidong; Kong, Xiaoyuan; and Wang, Xiaoqin, "Materials and methods for reducing inflammation by inhibition of the atrial natriuretic peptide receptor" (2011). USF Patents. 451.
https://digitalcommons.usf.edu/usf_patents/451
Assignees
University of South Florida
Filing Date
04/30/2007
Primary/U.S. Class
514/44
