Document Type
Patent
Publication Date
August 2011
Patent Number
7993870
Abstract
The present invention is a method of extracting infectious pathogens from a volume of blood including the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The fibrin lysis reagent is preferably composed of plasminogen and streptokinase frozen in coincident relation until the fibrin lysis reagent is needed whereby streptokinase enzymatically reacts with plasminogen to form plasmin upon thawing. The plasminogen is suspended in an aqueous salt solution prior to freezing including NaCl and Na3PO4.
Application Number
12/416,775
Recommended Citation
Ewert, Matt; Amuso, Philip; and Cannons, Andrew, "Early detection of pathogens in blood" (2011). USF Patents. 419.
https://digitalcommons.usf.edu/usf_patents/419
Assignees
University of South Florida
Filing Date
04/01/2009
Primary/U.S. Class
435/29
