Document Type
Patent
Publication Date
May 2011
Patent Number
7951924
Abstract
In one aspect, the present invention concerns RhoB variant polypeptides and isolated degenerate polynucleotides encoding the RhoB variant polypeptides. In another aspect, the present invention concerns nucleic acid constructs containing a polynucleotide encoding a RhoB variant polypeptide, and host cells genetically modified to express such polynucleotides. In another aspect, the present invention provides a method of inhibiting the growth of, and inducing apoptosis in, cancerous cells by contacting the cells with an effective amount of a RhoB variant.
Application Number
11/274,368
Recommended Citation
Sebti, Said M., "RhoB variants and methods of use" (2011). USF Patents. 403.
https://digitalcommons.usf.edu/usf_patents/403
Assignees
University of South Florida
Filing Date
11/14/2005
Primary/U.S. Class
536/231