Document Type
Patent
Publication Date
February 2011
Patent Number
7879545
Abstract
A classifier to predict cellular radiation sensitivity based on gene expression profiles in thirty-five cell lines from the NCI panel of 60 cancer cell lines (NCI-60), using a novel approach to predictive gene analysis. Three novel genes are provided, retinoblastoma binding protein 4 (RbAp48), G-protein signaling regulator 19 (RGS19) and ribose-5-phosphate isomerase A (R5PIA) whose expression values were correlated with radiation sensitivity.
Application Number
10/904,326
Recommended Citation
Torres-Roca, Javier F.; Yeatman, Timothy; and Eschrich, Steven, "Identification of novel targets for radio sensitization using a genomic-based radiation sensitivity classifier" (2011). USF Patents. 373.
https://digitalcommons.usf.edu/usf_patents/373
Assignees
H. Lee Moffitt Cancer Center and Research Institute, Inc.
Filing Date
11/04/2004
Primary/U.S. Class
435/6
