Document Type
Patent
Publication Date
May 2012
Patent Number
8183249
Abstract
The subject invention concerns materials and methods for inhibiting the Akt/PKB pathway. In one embodiment, a compound of the invention inhibits kinase activity and/or phosphorylation levels of Akt proteins. The subject invention also concerns methods for inhibiting or killing a cancer cell or other cell in which expression of an Akt protein is elevated or constitutively active, comprising contacting the cell with an effective amount of a compound of formula I. The subject invention also concerns methods for treating cancer or a tumor in a person or animal comprising administering all effective amount of a compound of formula I to the person or animal.
Application Number
12/172,831
Recommended Citation
Cheng, Jin Q.; Sun, Mei; and Sebti, Said M., "Inhibitors of AKT/PKB with anti-tumor activity" (2012). USF Patents. 324.
https://digitalcommons.usf.edu/usf_patents/324
Assignees
University of South Florida
Filing Date
07/14/2008
Primary/U.S. Class
514/266
