Document Type

Patent

Publication Date

May 2012

Patent Number

8178507

Abstract

There is provided a method of modulating the function of transcription factor by administering an effective amount of an oligonucleotide containing optimal nucleotide binding sites for the transcription factor. A therapeutic agent having an effective amount of an oligonucleotide for modulating function of transcription factors and a pharmaceutically acceptable carrier is also provided. Also provided is a treatment of patients having illnesses in which the activation of transcription factors play a role by administering to a patient an effective amount of an oligonucleotide which competitively binds the related transcription factor.

Application Number

12/391,943

Assignees

University of South Florida

Filing Date

02/24/2009

Primary/U.S. Class

514/44R

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