Document Type
Patent
Publication Date
April 2012
Patent Number
8153596
Abstract
The subject invention concerns compositions and methods for blocking cancer cell growth or proliferation and/or inducing cancer cell death. Compositions of the present invention are peptidomimetics that inhibit STAT function. Peptidomimetics of the invention display selective inhibition of specific STAT isoform homo-dimerization. The peptidomimetic probes of STAT1 function, described herein, provide the means to preferentially inhibit STAT1 over STAT3 through the exploration of the C-terminus.
Application Number
12/480,376
Recommended Citation
Sebti, Said M.; Hamilton, Andrew D.; Turkson, James; and Jove, Richard, "Use of SH2 STAT3/STAT1 peptidomimetics as anticancer drugs" (2012). USF Patents. 312.
https://digitalcommons.usf.edu/usf_patents/312
Assignees
University of South Florida
Filing Date
06/08/2009
Primary/U.S. Class
514/212
