Document Type
Patent
Publication Date
December 2013
Patent Number
8617839
Abstract
The present invention is a method of extracting infectious pathogens from a volume of blood including the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The fibrin lysis reagent is preferably composed of plasminogen and streptokinase frozen in coincident relation until the fibrin lysis reagent is needed whereby streptokinase enzymatically reacts with plasminogen to form plasmin upon thawing. The plasminogen is suspended in an aqueous salt solution prior to freezing including NaCl and Na3PO4.
Application Number
13/725,944
Recommended Citation
Ewert, Matt, "Early detection of pathogens in blood" (2013). USF Patents. 285.
https://digitalcommons.usf.edu/usf_patents/285
Assignees
University of South Florida
Filing Date
03/05/2013
Primary/U.S. Class
435/29
