Document Type
Patent
Publication Date
December 2013
Patent Number
8598511
Abstract
This invention enables a sensitivity enhancement in the detection of molecular compounds. A mass spectrometry analyte support with nanotube anchors are used to concentrate MALDI samples, specifically samples prepared with water-insoluble matrix compounds, on the anchor spot. The surface structure is established through patterned carbon nanotube anchor growth, providing a nucleation center for analyte and reducing sample precipitation on the surrounding MALDI wafer. Also disclosed is a method of creating a mass spectrometry support using patterned metal catalyst to grow carbon nanotubes. The carbon nanotubes enhance nucleation on specific areas of a sample plate to concentrate analyte/matrix deposit during droplet evaporation.
Application Number
12/398,710
Recommended Citation
Schlaf, Rudiger and Schumacher, Joshua, "Carbon nanotube anchor for mass spectrometer" (2013). USF Patents. 273.
https://digitalcommons.usf.edu/usf_patents/273
Assignees
University of South Florida
Filing Date
03/05/2009
Primary/U.S. Class
250/282