Document Type
Patent
Publication Date
December 2013
Patent Number
8598354
Abstract
Compounds of formula I:
or formula II:
or a pharmaceutically acceptable salt of formula I or formula II, wherein: R1 is H, hydroxyl, alkoxy, acyl, alkyl, cycloalkyl, aryl, or heteroaryl; R2 is methyl or haloalkyl; R4 is hydroxyl, carbonyloxy, or carbonyldioxy; and R3 is aliphatic, aryl, aralkyl, or alkylaryl; and R5, R6, R7 and R8 are each individually H, halogen, alkoxy, alkyl, haloalkyl, aryl, nitro, cyano, amino, amido, acyl, carboxyl, substituted carboxyl, or —SO2R10, wherein R10 is H, alkyl, amino or haloalkyl; provided that in formula I, R5 and R7 are not both H or R6 is not H or methoxy; and in formula II that if R4 is carbonyldioxy then R7 is not methoxy.
Application Number
13/153,350
Recommended Citation
Riscoe, Michael K.; Kelly, Jane X.; Winter, Rolf W.; Hinrichs, David J.; Smilkstein, Martin J.; Nilsen, Aaron; Burrows, Jeremy; Kyle, Dennis; Manetsch, Roman; Cross, Richard M.; Monastyrskyi, Andrii; and Flanigan, David L., "Compounds having antiparasitic or anti-infectious activity" (2013). USF Patents. 272.
https://digitalcommons.usf.edu/usf_patents/272
Assignees
University of South Florida Medicines for Malaria Venture
Filing Date
06/03/2011
Primary/U.S. Class
546/153
