Document Type
Patent
Publication Date
September 2013
Patent Number
8524947
Abstract
The present disclosure relates to acylsulfonamides and processes for their preparation. The processes involve a target-guided synthesis approach, whereby a thioacid and a sulfonyl azide are reacted in the presence of a biological target protein, a Bcl-2 family protein, to form the acylsulfonamide.
Application Number
12/867,812
Recommended Citation
Wang, Hong-Gang; Manetsch, Roman; Hu, Xiangdong; Kulkarni, Sameer; and Sun, Jiazhi, "Acylsulfonamides and processes for producing the same" (2013). USF Patents. 238.
https://digitalcommons.usf.edu/usf_patents/238
Assignees
University of South Florida H. Lee Moffitt Cancer Center and Research Institute, Inc.
Filing Date
02/23/2009
Primary/U.S. Class
564/85