Document Type
Patent
Publication Date
May 2013
Patent Number
8452408
Abstract
A method of treating neurological deficit in which the brain area affected is focally and precisely stimulated by the transient insertion and subsequent removal of a micro-needle. This insertion and subsequent removal of the micro-needle induces endogenous stem cells to proliferate, migrate and promote the brain's self-repair mechanisms. The micro-needle stimulation causes the birth of new neural cells within the brain as well as mobilizes bone marrow derived cells with a neuronal phenotype to migrate to the site of stimulation to repair and replace damaged neural cells. By repairing and/or replacing injured or dead cells, this approach will slow down the degenerative course of the disease and may result in reversal of symptoms.
Application Number
12/491,893
Recommended Citation
Song, Shijie and Sanchez-Ramos, Juan, "Promotion of brain self-repair mechanisms by stereotaxic micro-stimulation" (2013). USF Patents. 219.
https://digitalcommons.usf.edu/usf_patents/219
Assignees
University of South Florida Department of Veterans Affairs
Filing Date
06/25/2009
Primary/U.S. Class
607/45
