Document Type
Patent
Publication Date
February 2013
Patent Number
8367344
Abstract
Disclosed in a method of detecting cancer using IL-27 receptors. IL27R is a cytokine receptor identified as a novel oncogene from an acute myeloid leukemia patient. It induces cancer-like properties when expressed in cells and can activate a protein that causes various myeloid cell disorders. The data show cytokine receptors play unappreciated roles in mediating activation of signaling pathways in circulatory system cancers. Also method of screening for novel oncogenes using a functional, approach is disclosed using cytokine-dependent cells to screen for transforming events.
Application Number
12/761,649
Recommended Citation
Reuther, Gary Willard, "Method of detecting oncogenesis of hematopoietic cells" (2013). USF Patents. 197.
https://digitalcommons.usf.edu/usf_patents/197
Assignees
University of South Florida
Filing Date
04/16/2010
Primary/U.S. Class
435/614
