Document Type
Patent
Publication Date
January 2013
Patent Number
8361970
Abstract
Growth factor binding molecules having a plurality of peptide loops attached to a non-peptide organic scaffold, preferably having pseudo-six amino acid peptide loops with four amino acid sidechains. The growth factor binding molecules specifically bind various growth factors and are suitable for treating a subject having tumors or restinosis. In one embodiment a platelet-derived growth factor binding molecule is disclosed that is used to inhibit tumor growth and angiogenesis in solid tumors.
Application Number
12/622,295
Recommended Citation
Sebti, Said M. and Hamilton, Andrew D., "Growth factor binding molecules" (2013). USF Patents. 195.
https://digitalcommons.usf.edu/usf_patents/195
Assignees
University of South Florida Yale University
Filing Date
11/19/2009
Primary/U.S. Class
514/219
