Document Type

Article

Publication Date

February 2024

Patent Number

11896647

CPC

A61K 38/193 , A61K 38/1709 , A61K 38/1816 , A61K 38/19 , A61K 38/18 , A61K 38/20 , A61P 25/00 , A61P 25/28

Abstract

The subject invention concerns materials and methods for treating a person or animal having cognitive impairment. In one embodiment, the method comprises administering an effective amount of one or more inflammatory mediator(s), for example, fms-related tyrosine kinase 3 (Flt3) ligand, interleukin-6 (IL-6), macrophage migration inhibitory factor (MIF), interleukin-1 (IL-1), interleukin-3 (IL-3), erythropoietin (EPO), vascular endothelial growth factor A (VEGF-A), hypoxia-inducible transcription factor (HIF-1alpha), insulin like growth factor-1 (IGF-1), tumor necrosis factor (TNF), granulocyte colony-stimulating factor (G-CSF), granulocyte/macrophage colony-stimulating factor (GM-CSF), macrophage colony-stimulating factor (M-CSF), Stem Cell Factor (SCF), Darbepoetin (ARANESP), and metalloproteinases, to an animal or person in need of treatment.

Application Number

16/938736

Assignees

UNIVERSITY OF SOUTH FLORIDA

Filing Date

07/24/2020

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