Document Type

Article

Publication Date

January 2024

Patent Number

11878182

CPC

A61N 5/0622 , A61N 1/36164 , A61N 1/36167 , A61N 5/0601 , A61N 2005/0632 , A61N 2005/0663 , B82Y 5/00

Abstract

A method of modulating neural activity using a combination of electrical and optical stimulation transmitted via a gold nanoparticle covered nanoelectrode is presented. The combination of short-duration green visible light optical pulses with the complementary sub-threshold level electric current pulses are capable of producing action potentials in neurons. Cells were found to have a greater than a 5× survival rate using this hybrid stimulation method as compared to pure plasmonic/optical stimulation. The cell stimulation success rate was 3× greater with hybrid stimulation.

Application Number

17/239389

Assignees

University of South Florida

Filing Date

04/23/2021

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