Document Type
Article
Publication Date
December 2023
Patent Number
11844809
CPC
C12N 15/111 , C12N 15/113
Abstract
Disclosed herein are compositions and methods for inducing, promoting, or enhancing an immune response in a subject. For example, the disclosed compositions and methods can be used prophylactically to prevent viral/microbial infections or therapeutically to treat acute infections. In some embodiments, the disclosed method involves administering to the subject a composition comprising in vitro transcribed (IVT) RNA comprising short interspersed nuclear elements (SINEs), such as Alu repeats. In some embodiments, the disclosed compositions and methods can be used to induce, promote, or enhance any immune response in a subject, including an anti-viral, anti-microbial, anti-fungal, or anti-parasite response. In some embodiments, the disclosed compositions can be administered to any mucosal barrier, such as lungs or intestines, e.g. to enhance an innate immune response against a virus or pathogen.
Application Number
17/834611
Recommended Citation
Totary-Jain, Hana, "Strategy to increase anti-viral, anti-microbial, and anti-fungal defense" (2023). USF Patents. 1391.
https://digitalcommons.usf.edu/usf_patents/1391
Assignees
UNIVERSITY OF SOUTH FLORIDA
Filing Date
06/07/2022
