Document Type
Article
Publication Date
May 2022
Patent Number
11337931
CPC
A61K 9/5123, A61K 9/5169, A61K 31/436, A61K 31/5377, A61K 31/573, A61K 31/675, A61K 47/62, A61K 47/6925, A61K 9/513, A61P 9/00, C07K 7/06
Abstract
A targeting nanoparticle composition and method of treatment for diseases associated with major basement membrane components of blood vessels accessible from blood stream is presented. The composition includes pegylated perfluorocarbon nanoparticles having a targeting ligand attached that targets the basement membrane components, specifically collagen IV. The targeted nanoparticles may contain at least one pharmaceutically active agent capable of treating a glomerular disease such as lupus nephritis.
Application Number
16/950327
Recommended Citation
Liu, Ruisheng; Wickline, Samuel A.; Wei, Jin; Pan, Hua; and Zhang, Jie, "Nanoparticle delivery system for diseases associated with major basement membrane components of blood vessels accessible from blood stream" (2022). USF Patents. 1296.
https://digitalcommons.usf.edu/usf_patents/1296
Assignees
University of South Florida
Filing Date
11/17/2020
