Document Type
Article
Publication Date
September 2021
Patent Number
11110183
CPC
C12N 15/113, C12N 2310/531
Abstract
A multifunctional dendrimer nanoparticle and method of treating diseases of the posterior segment of the eye is presented. The functionalized polyamidoamine (PAMAM) dendrimer effectively delivers drugs and/or genes to the posterior eye, thereby providing for the effective, non-invasive, and topical treatment of diseased in the posterior eye. The multifunctional dendrimer nanoparticle has shRNA-encoding DNA and small molecule drug encapsulated cyclodextrin complexed to the outer surface of the dendrimer for delivery to the posterior segment of the eye.
Application Number
16/531734
Recommended Citation
Mohapatra, Shyam S.; Mohapatra, Subhra; and Markousta, Eleni, "Method of delivering genes and drugs to a posterior segment of an eye" (2021). USF Patents. 1261.
https://digitalcommons.usf.edu/usf_patents/1261
Assignees
University of South Florida
Filing Date
08/05/2019
